Partial impairment of c-Ret at tyrosine 1062 accelerates age-related hearing loss in mice

Neurobiology of Aging

Volumn 33, Issue 3, 2012, Pages 626.e25-626.e34

  Ohgami, Nobutaka ^a   Ida Eto, Michiru ^a   Sakashita, Naomi ^b   Sone, Michihiko ^c   Nakashima, Tsutomu ^c   Tabuchi, Keiji ^d   Hoshino, Tomofumi ^d   Shimada, Atsuyoshi ^e   Tsuzuki, Toyonori ^f   Yamamoto, Masahiko ^g   Sobue, Gen ^c   Jijiwa, Mayumi ^c   Asai, Naoya ^c   Hara, Akira ^d   Takahashi, Masahide ^c   Kato, Masashi ^a  

^a CHUBU UNIVERSITY   (Japan)

^b KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

^e INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^f NAGOYA DAINI RED CROSS HOSPITAL   (Japan)

^g AICHI GAKUIN UNIVERSITY   (Japan)

Author keywords

Age related deafness; C Ret; Neurodegeneration; Spiral ganglion neuron; Tyrosine kinase

Indexed keywords

PROTEIN RET; SERINE; SERINE 697; TYROSINE; TYROSINE 1062; UNCLASSIFIED DRUG;

ACOUSTIC NERVE FIBER; AGE RELATED HEARING LOSS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL COUNT; CELL DENSITY; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; HAIR CELL; HEARING LOSS; HETEROZYGOTE; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SOUND INTENSITY; SOUND TRANSMISSION; SPIRAL GANGLION; STRIA VASCULARIS;

EID: 84855765933     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2011.04.002     Document Type: Article

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