Continuous apple consumption induces oral tolerance in birch-pollen- associated apple allergy

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 67, Issue 2, 2012, Pages 280-285

  Kopac, P ^a,b,c   Rudin, M ^a   Gentinetta, T ^a,b   Gerber, R ^a   Pichler, Ch ^a   Hausmann, O ^a   Schnyder, B ^a   Pichler, W J ^a,b  

^a UNIVERSITY OF BERN   (Switzerland)

^b ADR AC GmbH   (Switzerland)

^c UNIVERSITY CLINIC OF RESPIRATORY AND ALLERGIC DISEASES   (Slovenia)

Author keywords

basophil activation test; birch pollen allergy; oral allergy syndrome; oral tolerance induction

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN G4;

ADULT; APPLE; ARTICLE; BIRCH; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOOD ALLERGY; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOREACTIVITY; MALE; ORAL ALLERGY SYNDROME; POLLEN ALLERGY; PRIORITY JOURNAL; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL; RHINOCONJUNCTIVITIS;

ADOLESCENT; ADULT; ALLERGENS; BETULA; CROSS REACTIONS; DESENSITIZATION, IMMUNOLOGIC; FEMALE; FOOD HYPERSENSITIVITY; HUMANS; IMMUNE TOLERANCE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; MALE; MALUS; MIDDLE AGED; POLLEN; RHINITIS, ALLERGIC, SEASONAL; YOUNG ADULT;

EID: 84855762732     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2011.02744.x     Document Type: Article

References (29)

1. Asero R,. Effects of birch pollen-specific immunotherapy on apple allergy in birch pollen-hypersensitive patients. Clin Exp Allergy 1998; 28: 1368-1373. (Pubitemid 28559011)
2. Bohle B,. The impact of pollen-related food allergens on pollen allergy. Allergy 2007; 62: 3-10. (Pubitemid 44902728)
3. Klinglmayr E, Hauser M, Zimmermann F, Dissertori O, Lackner P, Wopfner N, et al., Identification of B-cell epitopes of Bet v 1 involved in cross-reactivity with food allergens. Allergy 2009; 64: 647-651.
4. Vieths S, Jankiewicz A, Schoning B, Aulepp H,. Apple allergy: the IgE-binding potency of apple strains is related to the occurrence of the 18-kDa allergen. Allergy 1994; 49: 262-271. (Pubitemid 24131452)
5. Calvani M, Giorgio V, Miceli Sopo S,. Specific oral tolerance induction for food. A systematic review. Eur Ann Allergy Clin Immunol 2010; 42: 11-19.
6. Asero R,. Fennel, cucumber, and melon allergy successfully treated with pollen-specific injection immunotherapy. Ann Allergy Asthma Immunol 2000; 84: 460-462. (Pubitemid 30226983)
7. Bolhaar ST, Tiemessen MM, Zuidmeer L, van Leeuwen A, Hoffmann- Sommergruber K, Bruijnzeel-Koomen CA, et al., Efficacy of birch-pollen immunotherapy on cross-reactive food allergy confirmed by skin tests and double-blind food challenges. Clin Exp Allergy 2004; 34: 761-769. (Pubitemid 38736792)
8. Kelso JM, Jones RT, Tellez R, Yunginger JW,. Oral allergy syndrome successfully treated with pollen immunotherapy. Ann Allergy Asthma Immunol 1995; 74: 391-396.
9. Asero R,. How long does the effect of birch pollen injection SIT on apple allergy last? Allergy 2003; 58: 435-438. (Pubitemid 36605733)
10. Bucher X, Pichler WJ, Dahinden CA, Helbling A,. Effect of tree pollen specific, subcutaneous immunotherapy on the oral allergy syndrome to apple and hazelnut. Allergy 2004; 59: 1272-1276. (Pubitemid 39506725)
11. Herrmann D, Henzgen M, Frank E, Rudeschko O, Jager L,. Effect of hyposensitization for tree pollinosis on associated apple allergy. J Investig Allergol Clin Immunol 1995; 5: 259-267.
12. Moller C,. Effect of pollen immunotherapy on food hypersensitivity in children with birch pollinosis. Ann Allergy 1989; 62: 343-345. (Pubitemid 19116409)
13. Niederberger V, Reisinger J, Valent P, Krauth MT, Pauli G, van Hage M, et al., Vaccination with genetically modified birch pollen allergens: immune and clinical effects on oral allergy syndrome. J Allergy Clin Immunol 2007; 119: 1013-1016. (Pubitemid 46546426)
14. Walker SM, Durham SR, Till SJ, Roberts G, Corrigan CJ, Leech SC, et al., Immunotherapy for allergic rhinitis. Clin Exp Allergy 2011; 41: 1177-1200.
15. Mauro M, Russello M, Incorvaia C, Gazzola G, Frati F, Moingeon P, et al., Birch-apple syndrome treated with birch pollen immunotherapy. Int Arch Allergy Immunol 2011; 156: 416-422.
16. Hansen KS, Khinchi MS, Skov PS, Bindslev-Jensen C, Poulsen LK, Malling HJ,. Food allergy to apple and specific immunotherapy with birch pollen. Mol Nutr Food Res 2004; 48: 441-448. (Pubitemid 39524531)
17. Matthes A, Schmitz-Eiberger M,. Apple (Malus domestica L. Borkh.) allergen Mal d 1: effect of cultivar, cultivation system, and storage conditions. J Agric Food Chem 2009; 57: 10548-10553.
18. Hausmann O, Gentinetta T, Fux M, Ducrest S, Pichler W, Dahinden CA,. Robust expression of CCR3 as a single basophil selection marker in flow cytometry. Allergy 2011; 66: 85-91.
19. Mikkelsen S, Bibby B, Dolberg M, Dahl R, Hoffmann H,. Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapy. Clin Mol Allergy 2010; 1: 2.
20. Sancho AI, van Ree R, van Leeuwen A, Meulenbroek BJ, van de Weg EW, Gilissen LJ, et al., Measurement of lipid transfer protein in 88 apple cultivars. Int Arch Allergy Immunol 2008; 146: 19-26. (Pubitemid 351562939)
21. Vlieg-Boerstra BJ, Van De Weg WE, Van Der Heide S, Kerkhof M, Arens P, Heijerman-Peppelman G, et al., Identification of low allergenic apple cultivars using skin prick tests and oral food challenges. Allergy 2010; 66: 491-498.
22. Larenas-Linnemann D,. Oralair Birch, a recombinant major birch pollen allergen tablet for sublingual immunotherapy of allergic rhinitis caused by birch pollen. Curr Opin Investig Drugs 2010; 11: 586-596.
23. Larenas-Linnemann D,. Sublingual immunotherapy in children: complete and updated review supporting evidence of effect. Curr Opin Allergy Clin Immunol 2009; 9: 168-176.
24. Passalacqua G, Guerra L, Compalati E, Canonica GW,. The safety of allergen specific sublingual immunotherapy. Curr Drug Saf 2007; 2: 117-123. (Pubitemid 46805543)
25. Nucera E, Aruanno A, Lombardo C, Patriarca G, Schiavino D,. Apple desensitization in two patients with PR-10 proteins allergy. Allergy 2010; 65: 1060-1061.
26. Staden U, Rolinck-Werninghaus C, Brewe F, Wahn U, Niggemann B, Beyer K,. Specific oral tolerance induction in food allergy in children: efficacy and clinical patterns of reaction. Allergy 2007; 62: 1261-1269. (Pubitemid 47537518)
27. Bohle B, Zwolfer B, Heratizadeh A, Jahn-Schmid B, Antonia YD, Alter M, et al., Cooking birch pollen-related food: divergent consequences for IgE- and T cell-mediated reactivity in vitro and in vivo. J Allergy Clin Immunol 2006; 118: 242-249. (Pubitemid 43946469)
28. Polosa RHS, Church MK,. Adenosine as a pro-inflammatory mediator in asthma. Pulm Pharmacol 1989; 2: 21-26. (Pubitemid 19142692)
29. Cernadas JR, Brockow K, Romano A, Aberer W, Torres MJ, Bircher A, et al., General considerations on rapid desensitization for drug hypersensitivity-a consensus statement. Allergy 2010; 65: 1357-1366.