Toxic stress prioritizes and imbalances stem cell differentiation: Implications for new biomarkers and in vitro toxicology tests

Systems Biology in Reproductive Medicine

Volumn 58, Issue 1, 2012, Pages 33-40

  Rappolee, Daniel A ^a,b,c   Xie, Yufen ^a   Slater, Jill A ^a   Zhou, Sichang ^a,b   Puscheck, Elizabeth E ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WINDSOR   (Canada)

Author keywords

Differentiation; Stem cells; Stress; Stress enzymes; Toxicology

Indexed keywords

BIOLOGICAL MARKER;

BIOSYNTHESIS; CATABOLISM; CELL DIFFERENTIATION; CELL STRESS; CONFERENCE PAPER; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME SUBSTRATE; GESTATION PERIOD; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; STEM CELL; TOXICOLOGY;

ANIMAL TESTING ALTERNATIVES; ANIMALS; BIOMARKERS, PHARMACOLOGICAL; CELL DIFFERENTIATION; CELL LINEAGE; CELL SURVIVAL; CELLS, CULTURED; DEVELOPMENTAL BIOLOGY; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC DEVELOPMENT; HUMANS; MODELS, ANIMAL; RISK ASSESSMENT; STEM CELLS; STRESS, PHYSIOLOGICAL; TIME FACTORS; TOXICITY TESTS;

EID: 84855759056     PISSN: 19396368     EISSN: 19396368     Source Type: Journal    
DOI: 10.3109/19396368.2011.647381     Document Type: Conference Paper

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