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Volumn 47, Issue 1, 2012, Pages 5-14

Treosulfan-based conditioning before hematopoietic SCT: More than a BU look-alike

Author keywords

acute leukemia; SCT; treosulfan

Indexed keywords

BUSULFAN; CARMUSTINE; CYCLOPHOSPHAMIDE; ETOPOSIDE; FLUDARABINE; MELPHALAN; TREOSULFAN;

EID: 84855754876     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2011.88     Document Type: Review
Times cited : (80)

References (91)
  • 1
    • 0033768662 scopus 로고    scopus 로고
    • Harnessing graft-versus-malignancy: Non-myeloablative preparative regimens for allogeneic haematopoietic transplantation, an evolving strategy for adoptive immunotherapy
    • Champlin R, Khouri I, Shimoni A, Gajewski J, Kornblau S, Molldrem J et al. Harnessing graft-versus-malignancy: non-myeloablative preparative regimens for allogeneic haematopoietic transplantation, an evolving strategy for adoptive immunotherapy. Br J Haematol 2000; 111: 18-29.
    • (2000) Br J Haematol , vol.111 , pp. 18-29
    • Champlin, R.1    Khouri, I.2    Shimoni, A.3    Gajewski, J.4    Kornblau, S.5    Molldrem, J.6
  • 5
    • 0014876558 scopus 로고
    • Studies on epoxide formation from (2S,3S)-threitol 1,4- bismethanesulfonate. The preparation and biological activity of (2S,3S)-1,2-epoxy-3,4-butanediol 4-methanesulfonate
    • Feit PW, Rastrup-Andersen N, Matagne R. Studies on epoxide formation from (2S,3S)-threitol 1,4-bismethanesulfonate. The preparation and biological activity of (2S,3S)-1,2-epoxy-3,4-butanediol 4-methanesulfonate. J Med Chem 1970; 13: 1173-1175.
    • (1970) J Med Chem , vol.13 , pp. 1173-1175
    • Feit, P.W.1    Rastrup-Andersen, N.2    Matagne, R.3
  • 6
    • 0032943945 scopus 로고    scopus 로고
    • DNA alkylation and interstrand cross-linking by treosulfan
    • Hartley JA, O'Hare CC, Baumgart J. DNA alkylation and interstrand cross-linking by treosulfan. Br J Cancer 1999; 79: 264-266. (Pubitemid 29002295)
    • (1999) British Journal of Cancer , vol.79 , Issue.2 , pp. 264-266
    • Hartley, J.A.1    O'Hare, C.C.2    Baumgart, J.3
  • 7
    • 0033748741 scopus 로고    scopus 로고
    • Clinical phase i dose escalation and pharmacokinetic study of high-dose chemotherapy with treosulfan and autologous peripheral blood stem cell transplantation in patients with advanced malignancies
    • Scheulen ME, Hilger RA, Oberhoff C, Casper J, Freund M, Josten KM et al. Clinical phase I dose escalation and pharmacokinetic study of high-dose chemotherapy with treosulfan and autologous peripheral blood stem cell transplantation in patients with advanced malignancies. Clin Cancer Res 2000; 6: 4209-4216.
    • (2000) Clin Cancer Res , vol.6 , pp. 4209-4216
    • Scheulen, M.E.1    Hilger, R.A.2    Oberhoff, C.3    Casper, J.4    Freund, M.5    Josten, K.M.6
  • 8
    • 0031852331 scopus 로고    scopus 로고
    • The alkylator treosulfan shows activity towards human renal-cell carcinoma in vivo and in vitro
    • Kopf-Maier P. The alkylator treosulfan shows activity towards human renal-cell carcinoma in vivo and in vitro. In Vivo 1998; 12: 275-288. (Pubitemid 28379988)
    • (1998) In Vivo , vol.12 , Issue.3 , pp. 275-288
    • Kopf-Maier, P.1
  • 9
    • 0032803575 scopus 로고    scopus 로고
    • Treosulfan is an effective alkylating cytostatic for malignant melanoma in vitro and in vivo
    • Neuber K, tom Dieck A, Blodorn-Schlicht N, Itschert G, Karnbach C. Treosulfan is an effective alkylating cytostatic for malignant melanoma in vitro and in vivo. Melanoma Res 1999; 9: 125-132. (Pubitemid 29331520)
    • (1999) Melanoma Research , vol.9 , Issue.2 , pp. 125-132
    • Neuber, K.1    Tom Dieck, A.2    Blodorn-Schlicht, N.3    Itschert, G.4    Karnbach, C.5
  • 11
    • 17744402925 scopus 로고    scopus 로고
    • Potentiation of treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells. The role of BCL-2
    • DOI 10.1016/S0006-2952(97)00480-2, PII S0006295297004802
    • Reber U, Wullner U, Trepel M, Baumgart J, Seyfried J, Klockgether T et al. Potentiation of treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells: the role of bcl-2. Biochem Pharmacol 1998; 55: 349-359. (Pubitemid 28021748)
    • (1998) Biochemical Pharmacology , vol.55 , Issue.3 , pp. 349-359
    • Reber, U.1    Wullner, U.2    Trepel, M.3    Baumgart, J.4    Seyfried, J.5    Klockgether, T.6    Dichgans, J.7    Weller, M.8
  • 13
    • 0032191382 scopus 로고    scopus 로고
    • Treosulfan as an effective second-line therapy in ovarian cancer
    • DOI 10.1006/gyno.1998.5103
    • Gropp M, Meier W, Hepp H. Treosulfan as an effective second-line therapy in ovarian cancer. Gynecol Oncol 1998; 71: 94-98. (Pubitemid 28492400)
    • (1998) Gynecologic Oncology , vol.71 , Issue.1 , pp. 94-98
    • Gropp, M.1    Meier, W.2    Hepp, H.3
  • 15
    • 0347401320 scopus 로고    scopus 로고
    • Tandem high-dose chemotherapy for advanced ovarian carcinoma: Dose escalation of treosulfan in combination with carboplatin and etoposide
    • Wagner HM, Baumgart J, Andreesen R, Reichle A. Tandem high-dose chemotherapy for advanced ovarian carcinoma: dose escalation of treosulfan in combination with carboplatin and etoposide. Bone Marrow Transplant 2000; 26 (Suppl 1): 33.
    • (2000) Bone Marrow Transplant , vol.26 , Issue.SUPPL. 1 , pp. 33
    • Wagner, H.M.1    Baumgart, J.2    Andreesen, R.3    Reichle, A.4
  • 16
    • 84855719354 scopus 로고    scopus 로고
    • High-dose melphalan, DTIC and treosulfan (MDT) and PBPCT in previously treated metastatic breast and ovarian cancer
    • New Orleans, Louisiana, abstract 585
    • Baynes RD, Parchment R, Dansey RD (ed.). High-dose melphalan, DTIC and treosulfan (MDT) and PBPCT in previously treated metastatic breast and ovarian cancer. 36th Annual Meeting of the American Society of Clinical Oncology; 2000. New Orleans, Louisiana, abstract 585.
    • (2000) 36th Annual Meeting of the American Society of Clinical Oncology
    • Baynes, R.D.1    Parchment, R.2    Dansey, R.D.3
  • 18
    • 0037375930 scopus 로고    scopus 로고
    • Antileukaemic activity of treosulfan in xenografted human acute lymphoblastic leukaemias (ALL)
    • DOI 10.1016/S0959-8049(02)00767-0, PII S0959804902007670
    • Fichtner I, Becker M, Baumgart J. Antileukaemic activity of treosulfan in xenografted human acute lymphoblastic leukaemias (ALL). Eur J Cancer 2003; 39: 801-807. (Pubitemid 36315997)
    • (2003) European Journal of Cancer , vol.39 , Issue.6 , pp. 801-807
    • Fichtner, I.1    Becker, M.2    Baumgart, J.3
  • 19
    • 33747598242 scopus 로고    scopus 로고
    • Cytotoxicity of treosulfan and busulfan on pediatric tumor cell lines
    • DOI 10.1097/01.cad.0000215059.93437.89, PII 0000181320060700000007
    • Lanvers-Kaminsky C, Bremer A, Dirksen U, Jurgens H, Boos J. Cytotoxicity of treosulfan and busulfan on pediatric tumor cell lines. Anticancer Drugs 2006; 17: 657-662. (Pubitemid 44265866)
    • (2006) Anti-Cancer Drugs , vol.17 , Issue.6 , pp. 657-662
    • Lanvers-Kaminsky, C.1    Bremer, A.2    Dirksen, U.3    Jurgens, H.4    Boos, J.5
  • 20
    • 0346938576 scopus 로고    scopus 로고
    • Treosulfan-induced apoptosis in acute myeloid leukemia cells is accompanied by translocation of protein kinase C delta and enhanced by bryostatin-1
    • DOI 10.1016/j.exphem.2003.09.023
    • Schmidmaier R, Oellerich M, Baumgart J, Emmerich B, Meinhardt G. Treosulfan-induced apoptosis in acute myeloid leukemia cells is accompanied by translocation of protein kinase C delta and enhanced by bryostatin-1. Exp Hematol 2004; 32: 76-86. (Pubitemid 38064404)
    • (2004) Experimental Hematology , vol.32 , Issue.1 , pp. 76-86
    • Schmidmaier, R.1    Oellerich, M.2    Baumgart, J.3    Emmerich, B.4    Meinhardt, G.5
  • 21
    • 0141428908 scopus 로고    scopus 로고
    • Treosulfan is an effective inducer of cell death in myeloma cell lines and primary myeloma cells from patients
    • DOI 10.1046/j.1365-2141.2003.04525.x
    • Meinhardt G, Dayyani F, Jahrsdorfer B, Baumgart J, Emmerich B, Schmidmaier R. Treosulfan is an effective inducer of cell death in myeloma cell lines and primary myeloma cells from patients. Br J Haematol 2003; 122: 892-899. (Pubitemid 37174608)
    • (2003) British Journal of Haematology , vol.122 , Issue.6 , pp. 892-899
    • Meinhardt, G.1    Dayyani, F.2    Jahrsdorfer, B.3    Baumgart, J.4    Emmerich, B.5    Schmidmaier, R.6
  • 22
    • 0942296258 scopus 로고    scopus 로고
    • Bryostatin-1 enhances the proapoptotic effect of treosulfan in human acute myeloid leukemia cells, both in cell lines and primary leukemia cells
    • Abstract 574
    • Schmidmaier R, Baumgart J, Emmerich B, Meinhardt G. Bryostatin-1 enhances the proapoptotic effect of treosulfan in human acute myeloid leukemia cells, both in cell lines and primary leukemia cells. Onkologie 2002; 28 (Suppl 4): Abstract 574.
    • (2002) Onkologie , vol.28 , Issue.SUPPL. 4
    • Schmidmaier, R.1    Baumgart, J.2    Emmerich, B.3    Meinhardt, G.4
  • 24
    • 0037029687 scopus 로고    scopus 로고
    • Rationale for combination therapy of chronic myelogenous leukaemia with imatinib and irradiation or alkylating agents: Implications for pretransplant conditioning
    • DOI 10.1038/sj.bjc.6600242
    • Topaly J, Fruehauf S, Ho AD, Zeller WJ. Rationale for combination therapy of chronic myelogenous leukaemia with imatinib and irradiation or alkylating agents: implications for pretransplant conditioning. Br J Cancer 2002; 86: 1487-1493. (Pubitemid 34548074)
    • (2002) British Journal of Cancer , vol.86 , Issue.9 , pp. 1487-1493
    • Topaly, J.1    Fruehauf, S.2    Ho, A.D.3    Zeller, W.J.4
  • 25
    • 1842531123 scopus 로고    scopus 로고
    • Addition of treosulfan to a nonmyeloablative conditioning regimen results in enhanced chimerism and immunologic tolerance in an experimental allogeneic bone marrow transplant model
    • DOI 10.1016/j.bbmt.2003.11.004, PII S1083879103004786
    • Ploemacher RE, Johnson KW, Rombouts EJ, Etienne K, Westerhof GR, Baumgart J et al. Addition of treosulfan to a nonmyeloablative conditioning regimen results in enhanced chimerism and immunologic tolerance in an experimental allogeneic bone marrow transplant model. Biol Blood Marrow Transplant 2004; 10: 236-245. (Pubitemid 38456202)
    • (2004) Biology of Blood and Marrow Transplantation , vol.10 , Issue.4 , pp. 236-245
    • Ploemacher, R.E.1    Johnson, K.W.2    Rombouts, E.J.C.3    Etienne, K.4    Westerhof, G.R.5    Baumgart, J.6    White-Scharf, M.E.7    Down, J.D.8
  • 26
    • 0034307331 scopus 로고    scopus 로고
    • Comparison of different busulfan analogues for depletion of hematopoietic stem cells and promotion of donor-type chimerism in murine bone marrow transplant recipients
    • Westerhof GR, Ploemacher RE, Boudewijn A, Blokland I, Dillingh JH, McGown AT et al. Comparison of different busulfan analogues for depletion of hematopoietic stem cells and promotion of donor-type chimerism in murine bone marrow transplant recipients. Cancer Res 2000; 60: 5470-5478.
    • (2000) Cancer Res , vol.60 , pp. 5470-5478
    • Westerhof, G.R.1    Ploemacher, R.E.2    Boudewijn, A.3    Blokland, I.4    Dillingh, J.H.5    McGown, A.T.6
  • 28
    • 32144458104 scopus 로고    scopus 로고
    • Evaluation of chemosensitivity of human bone marrow stromal cells - Differences between common chemotherapeutic drugs
    • Schmidmaier R, Baumann P, Emmerich B, Meinhardt G. Evaluation of chemosensitivity of human bone marrow stromal cells-differences between common chemotherapeutic drugs. Anticancer Res 2006; 26: 347-350. (Pubitemid 43206096)
    • (2006) Anticancer Research , vol.26 , Issue.1 A , pp. 347-350
    • Schmidmaier, R.1    Baumann, P.2    Emmerich, B.3    Meinhardt, G.4
  • 29
    • 0033659651 scopus 로고    scopus 로고
    • Childhood all blasts retain phenotypic and genotypic characteristics upon long-term serial passage in NOD/SCID mice
    • Borgmann A, Baldy C, von Stackelberg A, Beyermann B, Fichtner I, Nurnberg P et al. Childhood all blasts retain phenotypic and genotypic characteristics upon long-term serial passage in NOD/SCID mice. Pediatr Hematol Oncol 2000; 17: 635-650.
    • (2000) Pediatr Hematol Oncol , vol.17 , pp. 635-650
    • Borgmann, A.1    Baldy, C.2    Von Stackelberg, A.3    Beyermann, B.4    Fichtner, I.5    Nurnberg, P.6
  • 31
    • 0038493879 scopus 로고    scopus 로고
    • Towards a myeloablative regimen with clinical potential: I. Treosulfan conditioning and bone marrow transplantation allow induction of donor-specific tolerance for skin grafts across full MHC barriers
    • DOI 10.1038/sj.bmt.1704094
    • van Pel M, van Breugel DW, Vos W, Ploemacher RE, Boog CJ. Towards a myeloablative regimen with clinical potential: I. Treosulfan conditioning and bone marrow transplantation allow induction of donor-specific tolerance for skin grafts across full MHC barriers. Bone Marrow Transplant 2003; 32: 15-22. (Pubitemid 36850275)
    • (2003) Bone Marrow Transplantation , vol.32 , Issue.1 , pp. 15-22
    • Van Pel, M.1    Van Breugel, D.W.J.G.2    Vos, W.3    Ploemacher, R.E.4    Boog, C.J.P.5
  • 32
    • 0842280795 scopus 로고    scopus 로고
    • Toward a myeloablative regimen with clinical potential: II. Treosulfan induces specific skin graft tolerance across haploidentical MHC barriers
    • DOI 10.1038/sj.bmt.1704333
    • van Pel M, van Breugel DW, Vos W, Ploemacher RE, Boog CJ. Toward a myeloablative regimen with clinical potential: II. Treosulfan induces specific skin graft tolerance across haploidentical MHC barriers. Bone Marrow Transplant 2004; 33: 153-159. (Pubitemid 38180926)
    • (2004) Bone Marrow Transplantation , vol.33 , Issue.2 , pp. 153-159
    • Van Pel, M.1    Van Breugel, D.W.J.G.2    Vos, W.3    Ploemacher, R.E.4    Boog, C.J.P.5
  • 33
    • 0030043388 scopus 로고    scopus 로고
    • Major salivary gland dysfunction in human acute and chronic graft-versus-host disease (GVHD)
    • Nagler R, Marmary Y, Krausz Y, Chisin R, Markitziu A, Nagler A. Major salivary gland dysfunction in human acute and chronic graft-versus-host disease (GVHD). Bone Marrow Transplant 1996; 17: 219-224. (Pubitemid 26057311)
    • (1996) Bone Marrow Transplantation , vol.17 , Issue.2 , pp. 219-224
    • Nagler, R.1    Marmary, Y.2    Krausz, Y.3    Chisin, R.4    Markitziu, A.5    Nagler, A.6
  • 35
    • 0036838788 scopus 로고    scopus 로고
    • Cytokines, viruses, and graft-versus-host disease
    • DOI 10.1097/00062752-200211000-00002
    • Holler E. Cytokines, viruses, and graft-versus-host disease. Curr Opin Hematol 2002; 9: 479-484. (Pubitemid 35191115)
    • (2002) Current Opinion in Hematology , vol.9 , Issue.6 , pp. 479-484
    • Holler, E.1
  • 36
    • 0028985580 scopus 로고
    • TNF alpha levels are increased during bone marrow transplantation conditioning in patients who develop acute GVHD
    • Remberger M, Ringden O, Markling L. TNF alpha levels are increased during bone marrow transplantation conditioning in patients who develop acute GVHD. Bone Marrow Transplant 1995; 15: 99-104.
    • (1995) Bone Marrow Transplant , vol.15 , pp. 99-104
    • Remberger, M.1    Ringden, O.2    Markling, L.3
  • 37
    • 0029617789 scopus 로고
    • Increased levels of soluble interleukin-2 receptor in veno-occlusive disease of the liver after allogenic bone marrow transplantation
    • Remberger M, Ringden O. Increased levels of soluble interleukin-2 receptor in veno-occlusive disease of the liver after allogenic bone marrow transplantation. Transplantation 1995; 60: 1293-1299. (Pubitemid 26005285)
    • (1995) Transplantation , vol.60 , Issue.11 , pp. 1293-1299
    • Remberger, M.1    Ringden, O.2
  • 38
    • 0035652154 scopus 로고    scopus 로고
    • Progress in CLL, chemotherapy, antibodies and transplantation
    • DOI 10.1016/S0753-3322(01)00139-1
    • Keating MJ. Progress in CLL, chemotherapy, antibodies and transplantation. Biomed Pharmacother 2001; 55: 524-528. (Pubitemid 34008435)
    • (2001) Biomedicine and Pharmacotherapy , vol.55 , Issue.9-10 , pp. 524-528
    • Keating, M.J.1
  • 39
    • 0034749380 scopus 로고    scopus 로고
    • A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome
    • DOI 10.1038/sj.bmt.1703215
    • Kroger N, Schetelig J, Zabelina T, Kruger W, Renges H, Stute N et al. A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome. Bone Marrow Transplant 2001; 28: 643-647. (Pubitemid 33014597)
    • (2001) Bone Marrow Transplantation , vol.28 , Issue.7 , pp. 643-647
    • Kroger, N.1    Schetelig, J.2    Zabelina, T.3    Kruger, W.4    Renges, H.5    Stute, N.6    Schrum, J.7    Kabisch, H.8    Siegert, W.9    Zander, A.R.10
  • 41
    • 37149000672 scopus 로고    scopus 로고
    • Fludarabine and treosulfan: A novel modified myeloablative regimen for allogeneic hematopoietic stem-cell transplantation with effective antileukemia activity in patients with acute myeloid leukemia and myelodysplastic syndromes
    • DOI 10.1080/10428190701671051, PII 788262790
    • Shimoni A, Hardan I, Shem-Tov N, Rand A, Yerushalmi R, Nagler A. Fludarabine and treosulfan: a novel modified myeloablative regimen for allogeneic hematopoietic stem-cell transplantation with effective antileukemia activity in patients with acute myeloid leukemia and myelodysplastic syndromes. Leuk Lymphoma 2007; 48: 2352-2359. (Pubitemid 350258301)
    • (2007) Leukemia and Lymphoma , vol.48 , Issue.12 , pp. 2352-2359
    • Shimoni, A.1    Hardan, I.2    Shem-Tov, N.3    Rand, A.4    Yerushalmi, R.5    Nagler, A.6
  • 42
    • 32844473063 scopus 로고    scopus 로고
    • Reduced-toxicity conditioning with treosulfan, fludarabine and ATG as preparative regimen for allogeneic stem cell transplantation (alloSCT) in elderly patients with secondary acute myeloid leukemia (sAML) or myelodysplastic syndrome (MDS)
    • DOI 10.1038/sj.bmt.1705259, PII 1705259
    • Kroger N, Shimoni A, Zabelina T, Schieder H, Panse J, Ayuk F et al. Reduced-toxicity conditioning with treosulfan, fludarabine and ATG as preparative regimen for allogeneic stem cell transplantation (alloSCT) in elderly patients with secondary acute myeloid leukemia (sAML) or myelodysplastic syndrome (MDS). Bone Marrow Transplant 2006; 37: 339-344. (Pubitemid 43250466)
    • (2006) Bone Marrow Transplantation , vol.37 , Issue.4 , pp. 339-344
    • Kroger, N.1    Shimoni, A.2    Zabelina, T.3    Schieder, H.4    Panse, J.5    Ayuk, F.6    Wolschke, C.7    Renges, H.8    Dahlke, J.9    Atanackovic, D.10    Nagler, A.11    Zander, A.12
  • 43
    • 77954731548 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem-cell transplantation in patients with hematologic malignancies after dose-escalated treosulfan/fludarabine conditioning
    • Casper J, Wolff D, Knauf W, Blau IW, Ruutu T, Volin L et al. Allogeneic hematopoietic stem-cell transplantation in patients with hematologic malignancies after dose-escalated treosulfan/ fludarabine conditioning. J Clin Oncol 2010; 28: 3344-3351.
    • (2010) J Clin Oncol , vol.28 , pp. 3344-3351
    • Casper, J.1    Wolff, D.2    Knauf, W.3    Blau, I.W.4    Ruutu, T.5    Volin, L.6
  • 44
    • 79551688903 scopus 로고    scopus 로고
    • Conditioning with treosulfan and fludarabine followed by allogeneic hematopoietic cell transplantation for high-risk hematologic malignancies
    • Nemecek ER, Guthrie KA, Sorror ML, Wood BL, Doney KC, Hilger RA et al. Conditioning with Treosulfan and Fludarabine Followed by Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies. Biol Blood Marrow Transplant 2010; 17: 341-350.
    • (2010) Biol Blood Marrow Transplant , vol.17 , pp. 341-350
    • Nemecek, E.R.1    Guthrie, K.A.2    Sorror, M.L.3    Wood, B.L.4    Doney, K.C.5    Hilger, R.A.6
  • 45
    • 79953706001 scopus 로고    scopus 로고
    • Retrospective analysis of treosulfanbased conditioning in comparison with standard conditioning in patients with myelodysplastic syndrome
    • Hilgendorf I, Wolff D, Gromke T, Trenschel R, Elmaagacli AH, Pichlmeier U et al. Retrospective analysis of treosulfanbased conditioning in comparison with standard conditioning in patients with myelodysplastic syndrome. Bone Marrow Transplant 2011; 46: 502-509.
    • (2011) Bone Marrow Transplant , vol.46 , pp. 502-509
    • Hilgendorf, I.1    Wolff, D.2    Gromke, T.3    Trenschel, R.4    Elmaagacli, A.H.5    Pichlmeier, U.6
  • 48
    • 31444444950 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced-intensity conditioning: The role of dose intensity
    • DOI 10.1038/sj.leu.2404037, PII 2404037
    • Shimoni A, Hardan I, Shem-Tov N, Yeshurun M, Yerushalmi R, Avigdor A et al. Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced-intensity conditioning: the role of dose intensity. Leukemia 2006; 20: 322-328. (Pubitemid 43148672)
    • (2006) Leukemia , vol.20 , Issue.2 , pp. 322-328
    • Shimoni, A.1    Hardan, I.2    Shem-Tov, N.3    Yeshurun, M.4    Yerushalmi, R.5    Avigdor, A.6    Ben-Bassat, I.7    Nagler, A.8
  • 49
    • 59349093509 scopus 로고    scopus 로고
    • Reduced-intensity conditioning regimen workshop: Defining the dose spectrum. Report of a workshop convened by the center for international blood and marrow transplant research
    • Giralt S, Ballen K, Rizzo D, Bacigalupo A, Horowitz M, Pasquini M et al. Reduced-intensity conditioning regimen workshop: defining the dose spectrum. Report of a workshop convened by the center for international blood and marrow transplant research. Biol Blood Marrow Transplant 2009; 15: 367-369.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 367-369
    • Giralt, S.1    Ballen, K.2    Rizzo, D.3    Bacigalupo, A.4    Horowitz, M.5    Pasquini, M.6
  • 50
    • 0035199030 scopus 로고    scopus 로고
    • Non-myeloablative stem cell transplantation (NST): Chimerism testing as guidance for immune therapeutic manipulations
    • Shimoni A, Nagler A. Non-myeloablative stem cell transplantation (NST): chimerism testing as guidance for immunetherapeutic manipulations. Leukemia 2001; 15: 1967-1975. (Pubitemid 33115006)
    • (2001) Leukemia , vol.15 , Issue.12 , pp. 1967-1975
    • Shimoni, A.1    Nagler, A.2
  • 51
    • 0034067082 scopus 로고    scopus 로고
    • Allogeneic peripheral blood stem cell transplantation using a fludarabine-based low intensity conditioning regimen for malignant lymphoma
    • Nagler A, Slavin S, Varadi G, Naparstek E, Samuel S, Or R. Allogeneic peripheral blood stem cell transplantation using a fludarabine-based low intensity conditioning regimen for malignant lymphoma. Bone Marrow Transplant 2000; 25: 1021-1028. (Pubitemid 30303589)
    • (2000) Bone Marrow Transplantation , vol.25 , Issue.10 , pp. 1021-1028
    • Nagler, A.1    Slavin, S.2    Varadi, G.3    Naparstek, E.4    Samuel, S.5    Or, R.6    Mandigers, C.M.7
  • 53
    • 84873064650 scopus 로고    scopus 로고
    • Final results of a prospective international phase II allogeneic transplant protocol with Treosulfan/ Fludarabine conditioning in 75 AML patients
    • Casper J, Holowiecki J, Giebel S, Beelen D, Trenschel R, Wandt H et al. Final results of a prospective international phase II allogeneic transplant protocol with Treosulfan/ Fludarabine conditioning in 75 AML patients. Onkologie 2009; 32 (Suppl 4): 29-30.
    • (2009) Onkologie , vol.32 , Issue.SUPPL. 4 , pp. 29-30
    • Casper, J.1    Holowiecki, J.2    Giebel, S.3    Beelen, D.4    Trenschel, R.5    Wandt, H.6
  • 54
    • 79953677743 scopus 로고    scopus 로고
    • Reduced-toxicity conditioning with treosulfan and fludarabine in allogeneic hematopoietic stem cell transplantation for myelodysplastic syndromes: Final results of an international prospective phase II trial
    • abstract O300
    • Ruutu T, Beelen DW, Finke J, Holowiecki J, Uharek L, Kienast J et al. Reduced-toxicity conditioning with treosulfan and fludarabine in allogeneic hematopoietic stem cell transplantation for myelodysplastic syndromes: final results of an international prospective phase II trial. Bone Marrow Transplantation 2009; 43(Suppl 1): 556 (abstract O300).
    • (2009) Bone Marrow Transplantation , vol.43 , Issue.SUPPL. 1 , pp. 556
    • Ruutu, T.1    Beelen, D.W.2    Finke, J.3    Holowiecki, J.4    Uharek, L.5    Kienast, J.6
  • 58
    • 0033693638 scopus 로고    scopus 로고
    • Melphalan-associated pulmonary toxicity following high-dose therapy with autologous hematopoietic stem cell transplantation
    • Akasheh MS, Freytes CO, Vesole DH. Melphalan-associated pulmonary toxicity following high-dose therapy with autologous hematopoietic stem cell transplantation. Bone Marrow Transplant 2000; 26: 1107-1109.
    • (2000) Bone Marrow Transplant , vol.26 , pp. 1107-1109
    • Akasheh, M.S.1    Freytes, C.O.2    Vesole, D.H.3
  • 59
    • 0034894543 scopus 로고    scopus 로고
    • Acute left ventricular failure following melphalan and fludarabine conditioning
    • DOI 10.1038/sj.bmt.1703098
    • Ritchie DS, Seymour JF, Roberts AW, Szer J, Grigg AP. Acute left ventricular failure following melphalan and fludarabine conditioning. Bone Marrow Transplant 2001; 28: 101-103. (Pubitemid 32707626)
    • (2001) Bone Marrow Transplantation , vol.28 , Issue.1 , pp. 101-103
    • Ritchie, D.S.1    Seymour, J.F.2    Roberts, A.W.3    Szer, J.4    Grigg, A.P.5
  • 60
    • 84873062130 scopus 로고    scopus 로고
    • Fludarabine and treosulfan conditioning for allogeneic stem cell transplantation; A dose-intense regimen with limited toxicity
    • Shimoni A, Rand A, Hardan I, Shem-Tov N, Volchek Y, Yerushalmi R et al. (eds). Fludarabine and treosulfan conditioning for allogeneic stem cell transplantation; a dose-intense regimen with limited toxicity. ASH Annual Meeting Abstracts 2010.
    • (2010) ASH Annual Meeting Abstracts
    • Shimoni, A.1    Rand, A.2    Hardan, I.3    Shem-Tov, N.4    Volchek, Y.5    Yerushalmi, R.6
  • 61
    • 33749841340 scopus 로고    scopus 로고
    • Unrelated versus related allogeneic stem cell transplantation after reduced intensity conditioning
    • DOI 10.1097/01.tp.0000233865.20232.51, PII 0000789020061015000010
    • Uzunel M, Remberger M, Sairafi D, Hassan Z, Mattsson J, Omazic B et al. Unrelated versus related allogeneic stem cell transplantation after reduced intensity conditioning. Transplantation 2006; 82: 913-919. (Pubitemid 44564037)
    • (2006) Transplantation , vol.82 , Issue.7 , pp. 913-919
    • Uzunel, M.1    Remberger, M.2    Sairafi, D.3    Hassan, Z.4    Mattsson, J.5    Omazic, B.6    Barkholt, L.7    Ringden, O.8
  • 62
    • 33748879386 scopus 로고    scopus 로고
    • Reduced intensity conditioning (RIC) haematopoietic cell transplants in elderly patients with AML
    • DOI 10.1016/j.beha.2006.06.007, PII S1521692606000466, Immune Therapy in Haematological Malignancies
    • Niederwieser D, Lange T, Cross M, Basara N, Al-Ali H. Reduced intensity conditioning (RIC) haematopoietic cell transplants in elderly patients with AML. Best Pract Res Clin Haematol 2006; 19: 825-838. (Pubitemid 44418026)
    • (2006) Best Practice and Research: Clinical Haematology , vol.19 , Issue.4 , pp. 825-838
    • Niederwieser, D.1    Lange, T.2    Cross, M.3    Basara, N.4    Al-Ali, H.5
  • 63
    • 0035869422 scopus 로고    scopus 로고
    • Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia
    • DOI 10.1182/blood.V97.6.1560
    • Olavarria E, Kanfer E, Szydlo R, Kaeda J, Rezvani K, Cwynarski K et al. Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia. Blood 2001; 97: 1560-1565. (Pubitemid 32217216)
    • (2001) Blood , vol.97 , Issue.6 , pp. 1560-1565
    • Olavarria, E.1    Kanfer, E.2    Szydlo, R.3    Kaeda, J.4    Rezvani, K.5    Cwynarski, K.6    Pocock, C.7    Dazzi, F.8    Craddock, C.9    Apperley, J.F.10    Cross, N.C.P.11    Goldman, J.M.12
  • 65
    • 0034157075 scopus 로고    scopus 로고
    • Allogeneic hematopoietic transplantation for acute and chronic myeloid leukemia: Non-myeloablative preparative regimens and induction of the graft-versus-leukemia effect
    • Shimoni A, Giralt S, Khouri I, Champlin R. Allogeneic hematopoietic transplantation for acute and chronic myeloid leukemia: non-myeloablative preparative regimens and induction of the graft-versus-leukemia effect. Curr Oncol Rep 2000; 2: 132-139.
    • (2000) Curr Oncol Rep , vol.2 , pp. 132-139
    • Shimoni, A.1    Giralt, S.2    Khouri, I.3    Champlin, R.4
  • 66
    • 34147144964 scopus 로고    scopus 로고
    • Reduced-intensity conditioning for myeloma: Lower nonrelapse mortality but higher relapse rates compared with myeloablative conditioning
    • DOI 10.1182/blood-2006-07-036848
    • Crawley C, Iacobelli S, Bjorkstrand B, Apperley JF, Niederwieser D, Gahrton G. Reduced-intensity conditioning for myeloma: lower nonrelapse mortality but higher relapse rates compared with myeloablative conditioning. Blood 2007; 109: 3588-3594. (Pubitemid 46572554)
    • (2007) Blood , vol.109 , Issue.8 , pp. 3588-3594
    • Crawley, C.1    Iacobelli, S.2    Bjorkstrand, B.3    Apperley, J.F.4    Niederwieser, D.5    Gahrton, G.6
  • 69
    • 77956569310 scopus 로고    scopus 로고
    • Second allogeneic hematopoietic stemcell transplantation using fludarabine treosulfan conditioning regimen in patients previously treated with busulfan-based regimens: Myeloablation with acceptable toxicity
    • Shimoni A, Rand A, Hardan I, Shem-Tov N, Volchek Y, Hannah M et al. (ed.). Second allogeneic hematopoietic stemcell transplantation using fludarabine treosulfan conditioning regimen in patients previously treated with busulfan-based regimens: myeloablation with acceptable toxicity. ASH Annual Meeting Abstracts 2009.
    • (2009) ASH Annual Meeting Abstracts
    • Shimoni, A.1    Rand, A.2    Hardan, I.3    Shem-Tov, N.4    Volchek, Y.5    Hannah, M.6
  • 70
    • 37549051777 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation for myelodysplastic syndrome
    • Barrett AJ, Savani BN. Allogeneic stem cell transplantation for myelodysplastic syndrome. Semin Hematol 2008; 45: 49-59.
    • (2008) Semin Hematol , vol.45 , pp. 49-59
    • Barrett, A.J.1    Savani, B.N.2
  • 71
    • 38149098489 scopus 로고    scopus 로고
    • Reduced-intensity conditioning followed by allogeneic hematopoietic cell transplantation for adult patients with myelodysplastic syndrome and myeloproliferative disorders
    • Laport GG, Sandmaier BM, Storer BE, Scott BL, Stuart MJ, Lange T et al. Reduced-intensity conditioning followed by allogeneic hematopoietic cell transplantation for adult patients with myelodysplastic syndrome and myeloproliferative disorders. Biol Blood Marrow Transplant 2008; 14: 246-255.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 246-255
    • Laport, G.G.1    Sandmaier, B.M.2    Storer, B.E.3    Scott, B.L.4    Stuart, M.J.5    Lange, T.6
  • 73
    • 75749124680 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem-cell transplantation for patients 50 years or older with myelodysplastic syndromes or secondary acute myeloid leukemia
    • Lim Z, Brand R, Martino R, van Biezen A, Finke J, Bacigalupo A et al. Allogeneic hematopoietic stem-cell transplantation for patients 50 years or older with myelodysplastic syndromes or secondary acute myeloid leukemia. J Clin Oncol 2010; 28: 405-411.
    • (2010) J Clin Oncol , vol.28 , pp. 405-411
    • Lim, Z.1    Brand, R.2    Martino, R.3    Van Biezen, A.4    Finke, J.5    Bacigalupo, A.6
  • 74
    • 51449098971 scopus 로고    scopus 로고
    • Treosulfan/fludarabine as an allogeneic hematopoietic stem cell transplant conditioning regimen for high-risk patients
    • Baronciani D, Rambaldi A, Iori AP, Di Bartolomeo P, Pilo F, Pettinau M et al. Treosulfan/fludarabine as an allogeneic hematopoietic stem cell transplant conditioning regimen for high-risk patients. Am J Hematol 2008; 83: 717-720.
    • (2008) Am J Hematol , vol.83 , pp. 717-720
    • Baronciani, D.1    Rambaldi, A.2    Iori, A.P.3    Di Bartolomeo, P.4    Pilo, F.5    Pettinau, M.6
  • 77
    • 77955859649 scopus 로고    scopus 로고
    • The role of reduced intensity preparative regimens in patients with thalassemia given hematopoietic transplantation
    • Bertaina A, Bernardo ME, Mastronuzzi A, La Nasa G, Locatelli F. The role of reduced intensity preparative regimens in patients with thalassemia given hematopoietic transplantation. Ann N Y Acad Sci 2010; 1202: 141-148.
    • (2010) Ann N y Acad Sci , vol.1202 , pp. 141-148
    • Bertaina, A.1    Bernardo, M.E.2    Mastronuzzi, A.3    La Nasa, G.4    Locatelli, F.5
  • 78
    • 54849419695 scopus 로고    scopus 로고
    • Treosulfan-based conditioning regimen for allogeneic haematopoietic stem cell transplantation in patients with thalassaemia major
    • Bernardo ME, Zecca M, Piras E, Vacca A, Giorgiani G, Cugno C et al. Treosulfan-based conditioning regimen for allogeneic haematopoietic stem cell transplantation in patients with thalassaemia major. Br J Haematol 2008; 143: 548-551.
    • (2008) Br J Haematol , vol.143 , pp. 548-551
    • Bernardo, M.E.1    Zecca, M.2    Piras, E.3    Vacca, A.4    Giorgiani, G.5    Cugno, C.6
  • 81
    • 0014801404 scopus 로고
    • A comparative study of the effects of antitumour and immunosuppressive drugs on antibody-forming and erythropoietic cells
    • Floersheim GL. A comparative study of the effects of antitumour and immunosuppressive drugs on antibody-forming and erythropoietic cells. Clin Exp Immunol 1970; 6: 861-870.
    • (1970) Clin Exp Immunol , vol.6 , pp. 861-870
    • Floersheim, G.L.1
  • 82
    • 77953958346 scopus 로고    scopus 로고
    • High-dose cyclophosphamide for autoimmunity and alloimmunity
    • Brodsky RA. High-dose cyclophosphamide for autoimmunity and alloimmunity. Immunol Res 2010; 47: 179-184.
    • (2010) Immunol Res , vol.47 , pp. 179-184
    • Brodsky, R.A.1
  • 83
    • 34447295685 scopus 로고    scopus 로고
    • Population pharmacokinetics of melphalan in paediatric blood or marrow transplant recipients
    • DOI 10.1111/j.1365-2125.2007.02862.x
    • Nath CE, Shaw PJ, Montgomery K, Earl JW. Population pharmacokinetics of melphalan in paediatric blood or marrow transplant recipients. Br J Clin Pharmacol 2007; 64: 151-164. (Pubitemid 47063242)
    • (2007) British Journal of Clinical Pharmacology , vol.64 , Issue.2 , pp. 151-164
    • Nath, C.E.1    Shaw, P.J.2    Montgomery, K.3    Earl, J.W.4
  • 85
    • 1342332856 scopus 로고    scopus 로고
    • Pharmacokinetics of high-dose chemotherapy
    • DOI 10.1038/sj.bmt.1704353
    • Nieto Y, Vaughan WP. Pharmacokinetics of high-dose chemotherapy. Bone Marrow Transplant 2004; 33: 259-269. (Pubitemid 38256557)
    • (2004) Bone Marrow Transplantation , vol.33 , Issue.3 , pp. 259-269
    • Nieto, Y.1    Vaughan, W.P.2
  • 86
    • 3042583641 scopus 로고    scopus 로고
    • Treosulfan/fludarabine: A new conditioning regimen in allogeneic transplantation
    • Casper J, Knauf W, Blau I, Ruutu T, Volin L, Wandt H et al. Treosulfan/fludarabine: a new conditioning regimen in allogeneic transplantation. Ann Hematol 2004; 83(Suppl 1): S70-S71.
    • (2004) Ann Hematol , vol.83 , Issue.SUPPL. 1
    • Casper, J.1    Knauf, W.2    Blau, I.3    Ruutu, T.4    Volin, L.5    Wandt, H.6
  • 87
    • 0029029247 scopus 로고
    • Busulfan concentration in relation to permanent alopecia in recipients of bone marrow transplants
    • Ljungman P, Hassan M, Bekassy AN, Ringden O, Oberg G. Busulfan concentration in relation to permanent alopecia in recipients of bone marrow transplants. Bone Marrow Transplant 1995; 15: 869-871.
    • (1995) Bone Marrow Transplant , vol.15 , pp. 869-871
    • Ljungman, P.1    Hassan, M.2    Bekassy, A.N.3    Ringden, O.4    Oberg, G.5
  • 88
    • 0024083939 scopus 로고
    • Interstitial pneumopathies caused by busulfan. Histologic, developmental and bronchoalveolar lavage analysis of 3 cases
    • Vergnon JM, Boucheron S, Riffat J, Guy C, Blanc P, Emonot A. Interstitial pneumopathies caused by busulfan. Histologic, developmental and bronchoalveolar lavage analysis of 3 cases. Rev Med Interne 1988; 9: 377-383.
    • (1988) Rev Med Interne , vol.9 , pp. 377-383
    • Vergnon, J.M.1    Boucheron, S.2    Riffat, J.3    Guy, C.4    Blanc, P.5    Emonot, A.6
  • 90
    • 41149155882 scopus 로고    scopus 로고
    • Prospective oral mucositis audit: Oral mucositis in patients receiving high-dose melphalan or BEAM conditioning chemotherapy-european blood and marrow transplantation mucositis advisory group
    • Blijlevens N, Schwenkglenks M, Bacon P, D'Addio A, Einsele H, Maertens J et al. Prospective oral mucositis audit: oral mucositis in patients receiving high-dose melphalan or BEAM conditioning chemotherapy-European Blood and Marrow Transplantation Mucositis Advisory Group. J Clin Oncol 2008; 26: 1519-1525.
    • (2008) J Clin Oncol , vol.26 , pp. 1519-1525
    • Blijlevens, N.1    Schwenkglenks, M.2    Bacon, P.3    D'addio, A.4    Einsele, H.5    Maertens, J.6


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