Contribution of G inhibitory protein alpha subunits in paradoxical hyperalgesia elicited by exceedingly low doses of morphine in mice

Life Sciences

Volumn 89, Issue 25-26, 2011, Pages 918-925

  Bianchi, Enrica ^a,b   Galeotti, Nicoletta ^c   Menicacci, Cristina ^b   Ghelardini, Carla ^c  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Antisense oligodeoxynucleotides; G proteins; Hot plate test; Hyperalgesia; Immunoprecipitation; Morphine

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ANTISENSE OLIGODEOXYNUCLEOTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MORPHINE; MU OPIATE RECEPTOR; NARCOTIC ANALGESIC AGENT; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HOT PLATE TEST; HYPERALGESIA; IMMUNOPRECIPITATION; IN VIVO CULTURE; MALE; MOUSE; NONHUMAN; PARADOXICAL HYPERALGESIA; PROTEIN BINDING; PROTEIN FUNCTION; TREATMENT RESPONSE; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DOSE RESPONSE; METABOLISM;

MUS;

ANALGESICS, OPIOID; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HYPERALGESIA; IMMUNOPRECIPITATION; MALE; MICE; MORPHINE; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, OPIOID, MU;

EID: 84855723461     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.09.025     Document Type: Article

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