Treatment adjustment and medication adherence for complex patients with diabetes, heart disease, and depression: A randomized controlled trial

Annals of Family Medicine

Volumn 10, Issue 1, 2012, Pages 6-14

  Lin, Elizabeth H B ^a   von Korff, Michael ^a   Ciechanowski, Paul ^b   Peterson, Do ^a   Ludman, Evette J ^a   Rutter, Carolyn M ^a   Oliver, Malia ^a   Young, Bessie A ^b   Gensichen, Jochen ^c   McGregor, Mary ^b   McCulloch, David K ^a   Wagner, Edward H ^a   Katon, Wayne J ^b  

^a CENTER FOR HEALTH STUDIES   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

Chronic care model; Collaborative care; Coronary heart disease; Depression; Diabetes; Medication adherence; Multicondition; Teamcare; Treat to target; Treatment adjustment

Indexed keywords

ANTIDEPRESSANT AGENT; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; INSULIN;

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; COMORBIDITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DIABETES MELLITUS; DOCTOR PATIENT RELATION; DRUG UTILIZATION; FEMALE; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; MULTICENTER STUDY; PATIENT CARE; PATIENT COMPLIANCE; PROFESSIONAL PRACTICE; RANDOMIZED CONTROLLED TRIAL; REGRESSION ANALYSIS; SELF CARE; STATISTICS;

ADULT; AGED; AGED, 80 AND OVER; ANTIDEPRESSIVE AGENTS; ANTIHYPERTENSIVE AGENTS; CARDIOVASCULAR DISEASES; COMORBIDITY; DEPRESSIVE DISORDER; DIABETES MELLITUS; DRUG UTILIZATION; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MEDICATION ADHERENCE; MIDDLE AGED; PATIENT CARE TEAM; PHYSICIAN-PATIENT RELATIONS; PROFESSIONAL PRACTICE; REGRESSION ANALYSIS; SELF CARE;

EID: 84855721369     PISSN: 15441709     EISSN: 15441717     Source Type: Journal    
DOI: 10.1370/afm.1343     Document Type: Article

References (55)

1. Schneider KM, O'Donnell BE, Dean D. Prevalence of multiple chronic conditions in the United States' Medicare population. Health Qual Life Outcomes. 2009;7:82.
2. Saydah SH, Fradkin J, Cowie CC. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA. 2004;291(3):335-342.
3. Starfield B, Lemke KW, Bernhardt T, Foldes SS, Forrest CB, Weiner JP. Comorbidity: implications for the importance of primary care in 'case' management. Ann Fam Med. 2003;1(1):8-14.
4. Bodenheimer T, Berry-Millett R. Care Management of Patients With Complex Health Care Needs, The Synthesis Project. Princeton, NJ: Robert Wood Johnson Foundation; 2009.
5. US Department of Health & Human Services. Multiple Chronic Conditions: A Strategic Framework. Washington, DC; 2010.
6. Parekh AK, Barton MB. The challenge of multiple comorbidity for the US health care system. JAMA. 2010;303(13):1303-1304.
7. Robert Wood Johnson Foundation. Partnership for solutions: better lives for people with chronic conditions. Grant Results Reports. 2006. http://www.partnershipforsolutions.org.
8. Stange KC. Is 'clinical inertia' blaming without understanding? Are competing demands excuses? Ann Fam Med. 2007;5(4):371-374.
9. Parchman ML, Pugh JA, Romero RL, Bowers KW. Competing demands or clinical inertia: the case of elevated glycosylated hemoglobin. Ann Fam Med. 2007;5(3):196-201.
10. Vogeli C, Shields AE, Lee TA, et al. Multiple chronic conditions: prevalence, health consequences, and implications for quality, care management, and costs. J Gen Intern Med. 2007;22(Suppl 3):391-395.
11. Baron RJ. What's keeping us so busy in primary care? A snapshot from one practice. N Engl J Med. 2010;362(17):1632-1636.
12. Turner BJ, Hollenbeak CS, Weiner M, Ten Have T, Tang SS. Effect of unrelated comorbid conditions on hypertension management. Ann Intern Med. 2008;148(8):578-586.
13. Kerr EA, Zikmund-Fisher BJ, Klamerus ML, Subramanian U, Hogan MM, Hofer TP. The role of clinical uncertainty in treatment decisions for diabetic patients with uncontrolled blood pressure. Ann Intern Med. 2008;148(10):717-727.
14. Phillips LS, Branch WT, Cook CB, et al. Clinical inertia. Ann Intern Med. 2001;135(9):825-834.
15. Glynn LG, Murphy AW, Smith SM, Schroeder K, Fahey T. Self-monitoring and other non-pharmacological interventions to improve the management of hypertension in primary care: a systematic review. Br J Gen Pract. 2010;60(581):e476-e488.
16. Martin S, Schneider B, Heinemann L, et al. Self-monitoring of blood glucose in type 2 diabetes and long-term outcome: an epidemiological cohort study. Diabetologia. 2006;49(2):271-278.
17. Schmittdiel JA, Uratsu CS, Karter AJ, et al. Why don't diabetes patients achieve recommended risk factor targets? Poor adherence versus lack of treatment intensifi cation. J Gen Intern Med. 2008; 23(5):588-594.
18. Lin EH, Rutter CM, Katon W, et al. Depression and advanced complications of diabetes: a prospective cohort study. Diabetes Care. 2010;33(2):264-269.
19. Ismail K, Winkley K, Stahl D, Chalder T, Edmonds M. A cohort study of people with diabetes and their fi rst foot ulcer: the role of depression on mortality. Diabetes Care. 2007;30(6):1473-1479.
20. Katon WJ, Rutter C, Simon G, et al. The association of comorbid depression with mortality in patients with type 2 diabetes. Diabetes Care. 2005;28(11):2668-2672.
21. Von Korff M, Katon W, Lin EH, et al. Potentially modifi able factors associated with disability among people with diabetes. Psychosom Med. 2005;67(2):233-240.
22. Simon GE, Katon WJ, Lin EHB, et al. Diabetes complications and depression as predictors of health service costs. Gen Hosp Psychiatry. 2005;27(5):344-351.
23. Ludman EJ, Katon W, Russo J, et al. Depression and diabetes symptom burden. Gen Hosp Psychiatry. 2004;26(6):430-436.
24. Ciechanowski PS, Katon WJ, Russo JE, Hirsch IB. The relationship of depressive symptoms to symptom reporting, self-care and glucose control in diabetes. Gen Hosp Psychiatry. 2003;25(4):246-252.
25. Golden SH, Lazo M, Carnethon M, et al. Examining a bidirectional association between depressive symptoms and diabetes. JAMA. 2008;299(23):2751-2759.
26. DiMatteo MR, Giordani PJ, Lepper HS, Croghan TW. Patient adherence and medical treatment outcomes: a meta-analysis. Med Care. 2002;40(9):794-811.
27. Lin EHB, Katon WVKM, Von Korff M, et al. Relationship of depression and diabetes self-care, medication adherence, and preventive care. Diabetes Care. 2004;27(9):2154-2160.
28. Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care. 2004;27(5):1218-1224.
29. van Bruggen R, Gorter K, Stolk RP, Zuithoff P, Klungel OH, Rutten GE. Refi ll adherence and polypharmacy among patients with type 2 diabetes in general practice. Pharmacoepidemiol Drug Saf. 2009; 18(11):983-991.
30. Katon WJ, Lin EH, Von Korff M, et al. Collaborative care for patients with depression and chronic illnesses. N Engl J Med. 2010;363(27): 2611-2620.
31. Derogatis LR, Rickels K, Uhlenhuth EH, Covi L. The Hopkins Symptom Checklist: a measure of primary symptom dimensions. In: Pichot P. Psychological Measurements in Psychopharmacology: Problems in Pharmacopsychiatry. Switzerland: S. Karger AG; 1974:79-110.
32. Von Korff M, Katon WJ, Lin EHB, et al. Functional outcomes of multi-condition collaborative care and successful ageing: results of randomized trial. BMJ. 2011;343:d6612.
33. Katon W, Lin EH, Von Korff M, et al. Integrating depression and chronic disease care among patients with diabetes and/or coronary heart disease: the design of the TEAMcare study. Contemp Clin Trials. 2010;31(4):312-322.
34. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606-613.
35. Katon W, Von Korff M, Lin E, et al. Collaborative management to achieve treatment guidelines. Impact on depression in primary care. JAMA. 1995;273(13):1026-1031.
36. Unutzer J, Katon W, Callahan CM, et al; IMPACT Investigators. Improving Mood-Promoting Access to Collaborative Treatment. Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial. JAMA. 2002;288(22): 2836-2845.
37. Wagner EH, Austin BT, Von Korff M. Organizing care for patients with chronic illness. Milbank Q. 1996;74(4):511-544.
38. Von Korff M, Gruman J, Schaefer J, Curry SJ, Wagner EH. Collaborative management of chronic illness. Ann Intern Med. 1997;127(12): 1097-1102.
39. Riddle MC, Rosenstock J, Gerich J; Insulin Glargine 4002 Study Investigators. The Treat-to-Target Trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care. 2003;26(11):3080-3086.
40. Epstein RM, Street RL Jr. The values and value of patient-centered care. Ann Fam Med. 2011;9(2):100-103.
41. Steiner JF, Koepsell TD, Fihn SD, Inui TS. A general method of compliance assessment using centralized pharmacy records. Description and validation. Med Care. 1988;26(8):814-823.
42. Andrade SE, Kahler KH, Frech F, Chan KA. Methods for evaluation of medication adherence and persistence using automated databases. Pharmacoepidemiol Drug Saf. 2006;15(8):565-574; discussion 575-567.
43. Toobert DJ, Hampson SE, Glasgow RE. The summary of diabetes self-care activities measure: results from 7 studies and a revised scale. Diabetes Care. 2000;23(7):943-950.
44. Katon W, Russo J, Lin EH, et al. Diabetes and poor disease control: is comorbid depression associated with poor medication adherence or lack of treatment intensifi cation? Psychosom Med. 2009;71(9): 965-972.
45. Kalbfleish J, Prentice R. The Statistical Analysis of Failure Time Data. New York, NY: John Wiley & Sons; 1980.
46. Kendrick T, Dowrick C, McBride A, et al. Management of depression in UK general practice in relation to scores on depression severity questionnaires: analysis of medical record data. BMJ. 2009;338:b750.
47. Maddox TM, Ross C, Tavel HM, et al. Blood pressure trajectories and associations with treatment intensifi cation, medication adherence, and outcomes among newly diagnosed coronary artery disease patients. Circ Cardiovasc Qual Outcomes. 2010;3(4):347-357.
48. Polonsky WH, Fisher L, Schikman CH, et al. A structured self-monitoring of blood glucose approach in type 2 diabetes encourages more frequent, intensive, and effective physician interventions: results from the STeP study. Diabetes Technol Ther. 2011;13(8):797-802.
49. Karter AJ, Ackerson LM, Darbinian JA, et al. Self-monitoring of blood glucose levels and glycemic control: the Northern California Kaiser Permanente Diabetes registry. Am J Med. 2001;111(1):1-9.
50. McManus RJ, Mant J, Bray EP, et al. Telemonitoring and self-management in the control of hypertension (TASMINH2): a randomised controlled trial. Lancet. 2010;376(9736):163-172.
51. Peikes D, Chen A, Schore J, Brown R. Effects of care coordination on hospitalization, quality of care, and health care expenditures among Medicare benefi ciaries: 15 randomized trials. JAMA. 2009; 301(6):603-618.
52. Coleman K, Austin BT, Brach C, Wagner EH. Evidence on the Chronic Care Model in the new millennium. Health Aff (Millwood). 2009;28 (1):75-85.
53. Areán PA, Ayalon L, Hunkeler E, et al; IMPACT Investigators. Improving depression care for older, minority patients in primary care. Med Care. 2005;43(4):381-390.
54. Gilbody S, Bower P, Fletcher J, Richards D, Sutton AJ. Collaborative care for depression: a cumulative meta-analysis and review of longer-term outcomes. Arch Intern Med. 2006;166(21):2314-2321.
55. Nutting PA, Crabtree BF, Miller WL, Stange KC, Stewart E, Jaén C. Transforming physician practices to patient-centered medical homes: lessons from the national demonstration project. Health Aff (Millwood). 2011;30(3):439-445.