Grade of atypia in dysplastic nevi and relationship with dermal fibroplasias;Displastik nevüslerde atipi derecesinin dermal fibroplazi ile i̇lişkisi

Turk Patoloji Dergisi/Turkish Journal of Pathology

Volumn 28, Issue 1, 2012, Pages 17-23

  Babacan, Ahmet ^a   Lebe, Banu ^a  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

Atypia; Dermal fibroplasia; Dysplastic nevus

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CELL ENLARGEMENT; CELL NUCLEUS; CELL PROLIFERATION; CELL SHAPE; CELL SIZE; CELL STRUCTURE; CHILD; CLINICAL FEATURE; DERMAL FIBROPLASIA; DISEASE SEVERITY; DYSPLASTIC NEVUS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MELANOCYTE; NUCLEOLUS; PRESCHOOL CHILD; SCHOOL CHILD; SCORING SYSTEM; SKIN FIBROSIS; TISSUE STRUCTURE;

ADOLESCENT; ADULT; AGED; CHILD; DERMIS; DYSPLASTIC NEVUS SYNDROME; FEMALE; FIBROBLASTS; FIBROSIS; HUMANS; HYPERPLASIA; MALE; MIDDLE AGED; NEOPLASM GRADING; SKIN NEOPLASMS; YOUNG ADULT;

EID: 84855719830     PISSN: 10185615     EISSN: 13095730     Source Type: Journal    
DOI: 10.5146/tjpath.2012.01092     Document Type: Article

References (37)

1. Clark WH, Reimer RR, Greene M, Ainsworth AM, Mastrangelo MJ: Origin of familial malignant melanomas from heritable melanocytic lesions. "Te B-K mole syndrome". Arch Dermatol 1978, 114: 732-738
2. Elder DE, Goldman LI, Goldman SC, Greene MH, Clark WH: Dysplastic nevus syndrome: a phenotypic association ofsporadic cutaneous melanoma. Cancer 1980, 46:1787-1794
3. Elder DE, Greene MH, Bondi EE, Clark WH: Acquired Melanocytic Nevi and Melanoma. Te Dysplastic Nevus Syndrome. In: Ackerman AB. (ed) Pathology of Malignant Melanoma. New York, Masson, 1981, 185-215
4. Seywright MM, Doherty VR, MacKie RM: Proposed alternative terminology and subclassifcation of so called "dysplastic naevi". J Clin Pathol 1986, 39: 189-194
5. Clemente C, Cochran AJ, Elder DE, Levene A, MacKie RM, Mihm MC, Rilke F, Cascinelli N, Fitzpatrick TB, Sober AJ: Histopathologic diagnosis of dysplastic nevi: concordance among pathologists convened by the World Health Organization Melanoma Programme. Hum Pathol 1991, 22: 313-319
6. Clark WH, Tucker MA, Goldstein AM: Parenchymal-stromal interactions in neoplasia. Teoretical considerations and observations in melanocytic neoplasia. Acta Oncol 1995, 34: 749-757
7. Clark WH., Tucker MA: Problems with lesions related to the development of malignant melanoma: common nevi, dysplastic nevi, malignant melanoma insitu, and radial growth phase malignant melanoma. Hum Pathol 1998, 29: 8-14
8. Rhodes AR, Mihm MC, Weinstock MA: Dysplastic melanocytic nevi: a reproducible histologic defnition emphasizing cellular morphology. Mod Pathol 1989, 2: 306-319
9. Rhodes AR, Melski JW, Sober AJ, Harrist TJ, Mihm MC, Fitzpatrick TB: Increased intraepidermal melanocyte frequency and size in dysplastic melanocytic nevi and cutaneous melanoma. A comparative quantitative study of dysplastic melanocytic nevi, superfcial spreading melanoma, nevocellular nevi, and solar lentigines. J Invest Dermatol 1983, 80: 452-459
10. Langer K, Rappersberger K, Steiner A, Konrad K, Wolf K: Te ultrastructure of dysplastic naevi: comparison with superfcial spreading melanoma and common naevocellular naevi. Arch Dermatol Res 1990, 282: 353-362
11. Hussein MR, Roggero E, Sudilovsky EC, Tuthill RJ, Wood GS, Sudilovsky O: Alterations of mismatch repair protein expression in benign melanocytic nevi, melanocytic dysplastic nevi, and cutaneous malignant melanomas. Am J Dermatopathol 2001, 23: 308-314
12. Lassam NJ, From L, Kahn HJ: Overexpression of p53 is a late event in the development of malignant melanoma. Cancer Res 1993, 53: 2235-2238
13. Smoller BR, McNutt NS, Hsu A: HMB-45 staining of dysplastic nevi. Support for a spectrum of progression toward melanoma. Am J Surg Pathol 1989, 13: 680-684
14. Takahashi H, Strutton GM, Parsons PG: Determination of proliferating fractions in malignant melanomas by anti-PCNA/ cyclin monoclonal antibody. Histopathology 1991, 18: 221-227
15. Hussein MR, Sun M, Tuthill RJ, Roggero E, Monti JA, Sudilovsky EC, Wood GS, Sudilovsky O: Comprehensive analysis of 112 melanocytic skin lesions demonstrates microsatellite instability in melanomas and dysplastic nevi, but not in benign nevi. J Cutan Pathol 2001, 28: 343-350
16. Birindelli S, Tragni G, Bartoli C, Ranzani GN, Rilke F, Pierotti MA, Pilotti S: Detection of microsatellite alterations in the spectrum of melanocytic nevi in patients with or without individual or family history of melanoma. Int J Cancer 2000, 86: 255-261
17. Park WS, Vortmeyer AO, Pack S, Duray PH, Böni R, Guerami AA, Emmert-Buck MR, Liotta LA, Zhuang Z: Allelic deletion at chromosome 9p21 (p16) and 17p13 (p53) in microdissected sporadic dysplastic nevus. Hum Pathol 1998, 29: 127-130
18. Böni R, Zhuang Z, Albuquerque A, Vortmeyer A, Duray P: Loss of heterozygosity detected on 1p and 9q in microdissected atypical nevi. Arch Dermatol 1998, 134: 882-883
19. Lee JY, Dong SM, Shin MS, Kim SY, Lee SH, Kang SJ, Lee JD, Kim CS, Kim SH, Yoo NJ: Genetic alterations of p16INK4a and p53 genes in sporadic dysplastic nevus. Biochem Biophys Res Commun 1997, 237: 667-672
20. Beitner H, Nakatani T, Hedblad MA: A transmission electron microscopical study of dysplastic naevi. Acta Derm Venereol 1990, 70: 411-416
21. de Wit PE, van't Hof-Grootenboer B, Ruiter DJ, Bondi R, Bröcker EB, Cesarini JP, Hastrup N, Hou-Jensen K, MacKie RM, Schefer E: Validity of the histopathological criteria used for diagnosing dysplastic naevi. An interobserver study by the pathology subgroup of the EORTC Malignant Melanoma Cooperative Group. Eur J Cancer 1993, 29: 831-839
22. Murphy GF, Mihm MCJ: Recognition and evaluation of cytological dysplasia in acquired melanocytic nevi. Hum Pathol 1999, 30: 506-512
23. Arumi-Uria M, McNutt NS, Finnerty B: Grading of atypia in nevi: correlation with melanoma risk. Mod Pathol 2003, 16: 764-771
24. Pozo L, Naase M, Cerio R, Blanes A, Diaz-Cano SJ: Critical analysis of histologic criteria for grading atypical (dysplastic) melanocytic nevi. Am J Clin Pathol 2001, 115: 194-204
25. Elder DE: Precursors to melanoma and their mimics: nevi of special sites. Mod Pathol 2006, 19: 4-20
26. Shea CR, Vollmer RT, Prieto VG: Correlating architectural disorder and cytologic atypia in Clark (dysplastic) melanocytic nevi. Hum Pathol 1999, 30: 500-505
27. Küpelioǧlu AA, Pabuççuoǧlu HU: Patoloji ve Sitopatoloji Laboratuvar Teknikleri. 1. baski{dotless}, İzmir, Dokuz Eylül Üniversitesi, 1995, 89-90
28. Shors AR, Kim S, White E, Argenyi Z, Barnhill RL, Duray P, Erickson L, Guitart J, Horenstein MG, Lowe L, Messina J, Rabkin MS, Schmidt B, Shea CR, Trotter MJ, Piepkorn MW: Dysplastic naevi with moderate to severe histological dysplasia: a risk factor for melanoma. Br J Dermatol 2006, 155: 988-993
29. Weinstock MA, Barnhill RL, Rhodes AR, Brodsky GL: Reliability of the histopathologic diagnosis of melanocytic dysplasia. Te Dysplastic Nevus Panel. Arch Dermatol 1997, 133: 953-958
30. Smoller BR, Egbert BM: Dysplastic nevi can be diagnosed and graded reproducibly: a longitudinal study. J Am Acad Dermatol 1992, 27: 399-402
31. Barnhill RL, Roush GC, Duray PH: Correlation of histologic architectural and cytoplasmic features with nuclear atypia in atypical (dysplastic) nevomelanocytic nevi. Hum Pathol 1990, 21: 51-58
32. Balkau D, Gartmann H, Wischer W, Grootens A, Hagemeier HH, Hundeiker M, Suter L: Architectural features in melanocytic lesions with cellular atypia. Dermatologica 1988, 177: 129-137
33. Culpepper KS, Granter SR, McKee PH: My approach to atypical melanocytic lesions. J Clin Pathol 2004, 57: 1121-1131
34. Friedman RJ, Farber MJ, Warycha MA, Papathasis N, Miller MK, Heilman ER: Te "dysplastic" nevus. Clin Dermatol 2009, 27: 103-115
35. Schaumburg-Lever G, Lever I, Fehrenbacher B, Möller H, Bischof B, Kaiserling E, Garbe C, Rassner G: Melanocytes in nevi and melanomas synthesize basement membrane and basement membrane-like material. An immunohistochemical and electron microscopic study including immunoelectron microscopy. J Cutan Pathol 2000, 27: 67-75
36. Giehl KA, Nägele U, Volkenandt M, Berking C: Protein expression of melanocyte growth factors (bFGF, SCF) and their receptors (FGFR-1, c-kit) in nevi and melanoma. J Cutan Pathol 2007, 34: 7-14
37. Clark WH, Hood AF, Tucker MA, Jampel RM: Atypical melanocytic nevi of the genital type with a discussion of reciprocal parenchymal-stromal interactions in the biology of neoplasia. Hum Pathol 1998, 29: 1-24