Toxicogenomic investigation on rat testicular toxicity elicited by 1,3-dinitrobenzene

Toxicology

Volumn 290, Issue 2-3, 2011, Pages 169-177

  Matsuyama, Takuya ^a   Niino, Noriyo ^a   Kiyosawa, Naoki ^a   Kai, Kiyonori ^a   Teranishi, Munehiro ^a   Sanbuissho, Atsushi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

1,3 Dinitrobenzene; Biomarker; Microarray; Testicular toxicity; Toxicogenomics

Indexed keywords

1,3 DINITROBENZENE; CDH2 PROTEIN; CTNNA1 PROTEIN; GSN PROTEIN; ITGB1 PROTEIN; LAMC3 PROTEIN; METHYLTESTOSTERONE; NECTIN 2; PROTEIN; UNCLASSIFIED DRUG; VCL PROTEIN; ZYX PROTEIN; 3 DINITROBENZENE; 3-DINITROBENZENE; NITROBENZENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL DEATH; CONTROLLED STUDY; DOWN REGULATION; EPIDIDYMIS; GENE EXPRESSION; GENOMICS; MALE; MICROARRAY ANALYSIS; NONHUMAN; PACHYTENE; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCTIVE TOXICITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINIFEROUS TUBULE EPITHELIUM; SERTOLI CELL; SPERMATID; SPERMATOCYTE; SPERMATOGONIUM; TESTICULAR TOXICITY; TESTIS DISEASE; UPREGULATION; ANIMAL; DNA MICROARRAY; DOSE RESPONSE; DRUG EFFECT; FISCHER 344 RAT; GENETICS; METABOLISM; PATHOLOGY; TESTIS; TOXICOGENETICS;

RATTUS;

ANIMALS; CELL ADHESION; DINITROBENZENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PACHYTENE STAGE; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERTOLI CELLS; SPERMATOCYTES; TESTIS; TOXICOGENETICS; UP-REGULATION;

EID: 84855719702     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.09.001     Document Type: Article

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