Antiplasmodial quinones from Pentas longiflora and Pentas lanceolata

Planta Medica

Volumn 78, Issue 1, 2012, Pages 31-35

  Endale, Milkyas ^a   Alao, John Patrick ^b   Akala, Hoseah M ^c   Rono, Nelson K ^a   Eyase, Fredrick L ^c   Derese, Solomon ^a   Ndakala, Albert ^a   Mbugua, Martin ^a   Walsh, Douglas S ^c   Sunnerhagen, Per ^b   Erdelyi, Mate ^b   Yenesew, Abiy ^a  

^a UNIVERSITY OF NAIROBI   (Kenya)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c U S ARMY   (United States)

Author keywords

5,6 dihydroxydamnacanthol; anthraquinone; malaria; Pentas lanceolata; Pentas longiflora; pyranonaphthoquinone; Rubiaceae

Indexed keywords

2 METHYLANTHRAQUINONE; 5,6 DIHYDROXYDAMNACANTHOL; ANTHRAQUINONE DERIVATIVE; ANTIMALARIAL AGENT; CHLOROQUINE; DAMNACANTHAL; DAMNACANTHOL; DICHLOROMETHANE; LUCIDIN OMEGA METHYL ETHER; MEFLOQUINE; METHANOL; MOLLUGIN; NAPHTHALENE DERIVATIVE; NORDAMNACANTHAL; PENTALONGIN; PENTAS LANCEOLATA EXTRACT; PENTAS LONGIFLORA EXTRACT; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PSYCHORUBRIN; QUINONE DERIVATIVE; RUBIADIN; RUBIADIN 1 METHYL ETHER; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ANTIMALARIAL DRUG RESISTANCE; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; COLUMN CHROMATOGRAPHY; IC 50; IN VITRO STUDY; MASS SPECTROMETRY; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PENTAS LANCEOLATA; PENTAS LONGIFLORA; PLANT ROOT; PLASMODIUM FALCIPARUM;

ANTHRAQUINONES; ANTIMALARIALS; DRUG RESISTANCE; INHIBITORY CONCENTRATION 50; PLANT EXTRACTS; PLANT ROOTS; PLASMODIUM FALCIPARUM; QUINONES; RUBIACEAE;

PENTAS; PENTAS LANCEOLATA; PENTAS LONGIFLORA; PLASMODIUM FALCIPARUM; RUBIACEAE;

EID: 84855710449     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0031-1280179     Document Type: Article

References (31)

1. WHO. World Malaria Report 2008. Geneva WHO 2008 9
2. Heyneman D. The worldwide burden of parasitic disease. In: Leech J Sande M Root R editors Parasitic infections. New York Churchill Livingstone 1988 11-32
3. Wongsrichanalai C, Pickard A L., Wernsdorfer W H., Meshnick S R. Epidemiology of drug-resistant malaria. Lancet Infect Dis 2002 2 209-218 (Pubitemid 34464751)
4. Willox M L., Bodeker G. Traditional herbal medicines for malaria. Br Med J 2004 329 1156-1159 (Pubitemid 39524776)
5. Njoroge N G., Bussmann W R., Gemmill B, Newton L E., Ngumi V W. Utilisation of weed species as sources of traditional medicines in central Kenya. Lyonia 2004 7 71-87
6. Kokwaro J O. Medicinal Plants of East Africa. Nairobi University of Nairobi Press 2010 247-248
7. Wanyoike G N., Chhabra S C., Lang'at-Thoruwa C C., Omar S A. Brine shrimp toxicity and antiplasmodial activity of five Kenyan medicinal plants. J Ethnopharmacol 2004 90 129-133 (Pubitemid 38091697)
8. Koch A, Tamez P, Pezzuto J, Soejarto D. Evaluation of plants used for antimalarial treatment by the Massai of Kenya. J Ethnopharmacol 2005 101 95-99 (Pubitemid 41265606)
9. Nayak B S., Vinutha B, Geetha B, Sudha B. Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats. Fitoterapia 2005 76 671-675 (Pubitemid 41688386)
10. Juma W P., Akala H M., Eyase F L., Muiva L M., Heydenreich M, Okalebo F A., Gitu P M., Peter M G., Walsh D S., Imbuga M, Yenesew A. Terpurinflavone: An antiplasmodial flavone from the stem of Tephrosia Purpurea. Phytochem Lett 2011 4 176-178
11. 13NMR spectral assignments of pentalongin. Magn Reson Chem 1993 31 329-330
12. Hari L, De Buyck L F., De Pooter H L. Naphthoquinoid pigments from Pentas longiflora. Phytochemistry 1991 30 1726-1727
13. El Hady S, Bukuru J, Kesteleyn B, van Puyvelde L, De Kimpe N, Van T N. New pyranonaphthoquinone and pyranonaphthohydroquinone from the roots of Pentas longiflora. J Nat Prod 2002 65 1377-1379
14. Hayashi T, Smith F T., Lee K H. Antitumor agents. 89. Psychorubrin, a new cytotoxic naphthoquinone from Psychotria rubra and its structure-activity relationships. J Med Chem 1987 30 2005-2008 (Pubitemid 18046055)
15. Liu R, Lu Y, Wu T, Pan Y. Simultaneous isolation and purification of mollugin and two anthraquinones from Rubia cordifolia by HSCCC. Chromatographia 2008 68 95-99
16. Van T, De Kimpe N. Synthesis of pyranonaphthoquinone antibiotics involving the ring closing metathesis of a vinyl ether. Tetrahedron Lett 2004 45 3443-3446 (Pubitemid 38471630)
17. Puyvelde L V., Geysen D, Ayobangira F X., Hakizamungu E, Nshimyimana A, Kalise A. Screening of medicinal plants of Rwanda for acaricidal activity. J Ethnopharmacol 1985 13 209-215 (Pubitemid 15035533)
18. Ho L K., Don M J., Chen H C., Yeh S F., Chen J M. Inhibition of hepatitis B surface antigen secretion on human hepatoma cells. Components from Rubia cordifolia. J Nat Prod 1996 59 330-333
19. Kusamba C, Federici E, De Vicente Y, Galeffi C. The anthraquinones of Pentas zanzibarica. Fitoterapia 1993 64 18-22 (Pubitemid 23122404)
20. Adesogan E K. Anthraquinones and anthraquinols from Morinda lucida: The biogenetic significance of oruwal and oruwalol. Tetrahedron 1973 29 4099-4102
21. Ferrari F, Monache G D., Alves de Lima R. Two naphthopyran derivatives from Faramea cyanea. Phytochemistry 1985 24 2753-2755
22. Koumaglo K, Gbeassor M, Nikabu O, De Souza C, Werner W. Effects of three compounds extracted from Morinda lucida on Plasmodium falciparum. Planta Med 1992 58 533-534
23. Scott A I. Interpretation of the ultraviolet spectra of natural products. Oxford Pergamon Press 1964 286-289
24. Schripsema J, Dagnino D. Elucidation of the substitution pattern of 9, 10-anthraquinones through the chemical shifts of peri -hydroxyl protons. Phytochemistry 1996 42 177-184
25. Han Y S., Van der Heijen R, Verpoorte R. Biosynthesis of anthraquinones in cell cultures of Rubiaceae. Plant Cell Tissue Organ Cult 2001 67 201-220 (Pubitemid 34020944)
26. Cali I, Tasdemir D, Ireland C M., Sticher O. Lucidin type anthraquinone glycosides from Putoria calabrica. Chem Pharm Bull (Tokyo) 2002 50 701-702 (Pubitemid 41694950)
27. Gonzalez A, Barrosso J T., Cardona R J., Medina J M., Rodriguez Luis F. Qumica de la Rubiceas. II. Componentes de la Putoria calbrica Perss. Anales de Quimica 1977 73 538-545
28. Schripsema J, Ramos V A., Verpoorte R. Robustaquinones, novel anthraquinones from an elicited Cinchona robusta suspension culture. Phytochemistry 1999 51 55-60 (Pubitemid 29232781)
29. Leistner E. Biosynthesis of morindone and alizarin in intact plants and cell suspension cultures of Morinda citrifolia. Phytochemistry 1973 12 1669-1674
30. Ee G C. L., Wen Y P., Sukari M A., Go R, Lee H L. A new anthraquinone from Morinda citrifolia roots. Nat Prod Res 2009 23 1322-1329
31. Osman C P., Ismail N H., Ahmad R, Ahmat N, Awang K, Jaafar F M. Anthraquinones with antiplasmodial activity from the roots of Rennellia elliptica Korth. (Rubiaceae). Molecules 2010 15 7218-7226