A noninvasive [ 99mTc]DTPA SPECT/CT imaging methodology as a measure of lung permeability in a guinea pig model of COPD

Molecular Imaging and Biology

Volumn 13, Issue 5, 2011, Pages 923-929

  Wu, Yanjun ^a   Kotzer, Charles J ^a   Makrogiannis, Sokratis ^a   Logan, Gregory A ^a   Haley, Hyking ^a   Barnette, Mary S ^a   Sarkar, Susanta K ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

99mTc DTPA; Aerosol inhalation; Clearance rate; COPD; Lung permeability; SPECT CT imaging

Indexed keywords

PENTETATE TECHNETIUM TC 99M; DIAGNOSTIC AGENT;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPUTED TOMOGRAPHY SCANNER; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; GUINEA PIG; LUNG CLEARANCE; LUNG FUNCTION; LUNG PERMEABILITY; MALE; NEBULIZER; NON INVASIVE MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SMOKING; ANIMAL; COMPUTER ASSISTED TOMOGRAPHY; DISEASE MODEL; LUNG; METABOLISM; METHODOLOGY; SCINTISCANNING;

CAVIA;

ANIMALS; DISEASE MODELS, ANIMAL; GUINEA PIGS; LUNG; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TECHNETIUM TC 99M PENTETATE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84855679364     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-010-0423-9     Document Type: Article

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