Hair cell toxicity in anti-cancer drugs: Evaluating an anticancer drug library for independent and synergistic toxic effects on hair cells using the zebrafish lateral line

JARO - Journal of the Association for Research in Otolaryngology

Volumn 12, Issue 6, 2011, Pages 719-728

  Hirose, Yoshinobu ^a,b,c   Simon, Julian A ^d   Ou, Henry C ^a,b,e  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d Fred Hutchinson Cancer Research Center   (United States)

^e SEATTLE CHILDREN S HOSPITAL   (United States)

Author keywords

Anti cancer drugs; Hair cell death; Zebrafish

Indexed keywords

ALLOPURINOL; BLEOMYCIN; BUSULFAN; CARBOPLATIN; CARMUSTINE; CHLORMETHINE; CISPLATIN; DACTINOMYCIN; DOXORUBICIN; ERLOTINIB; ESTRAMUSTINE; EXEMESTANE; FLOXURIDINE; FLUOROURACIL; GEMCITABINE; IMATINIB; LOMUSTINE; NAVELBINE; OXALIPLATIN; PENTOSTATIN; PROCARBAZINE; RALOXIFENE; RAPAMYCIN; SUNITINIB; TAMOXIFEN CITRATE; TENIPOSIDE; THALIDOMIDE; UNINDEXED DRUG; VINBLASTINE; VINCRISTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG POTENTIATION; DRUG SCREENING; EMBRYO; HAIR CELL; HEARING LOSS; LATERAL LINE SYSTEM; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; ZEBRA FISH;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL ASSAY; CELL COUNT; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; FEMALE; HAIR CELLS, AUDITORY, INNER; HUMANS; LATERAL LINE SYSTEM; MALE; ZEBRAFISH;

EID: 84855651444     PISSN: 15253961     EISSN: 14387573     Source Type: Journal    
DOI: 10.1007/s10162-011-0278-z     Document Type: Article

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