TNF-α response of vascular endothelial and vascular smooth muscle cells involve differential utilization of ASK1 kinase and p73

Cell Death and Differentiation

Volumn 19, Issue 2, 2012, Pages 274-283

  Rastogi, S ^a,b   Rizwani, W ^a,c   Joshi, B ^a,d   Kunigal, S ^a   Chellappan, S P ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b KLOX Technologies Inc   (Canada)

^c M D ANDERSON CANCER CENTER ORLANDO   (United States)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

apoptosis; ASK1; E2F1; endothelial cells; p73; TNF

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; PROTEIN P73; RETINOBLASTOMA PROTEIN; THYMIDYLATE SYNTHASE; TRANSCRIPTION FACTOR E2F1; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

AORTA; APOPTOSIS; CELL PROLIFERATION; CYTOPROTECTION; DNA-BINDING PROTEINS; E2F1 TRANSCRIPTION FACTOR; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE SILENCING; HUMANS; MAP KINASE KINASE KINASE 5; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RETINOBLASTOMA PROTEIN; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84855642918     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.93     Document Type: Article

References (40)

1. Beg AA, Baltimore D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 1996; 274: 782-784. (Pubitemid 26398258)
2. Wang X, Yue TL, Barone FC, White RF, Gagnon RC, Feuerstein GZ. Concomitant cortical expression of TNF-alpha and IL-1 beta mRNAs follows early response gene expression in transient focal ischemia. Mol Chem Neuropathol 1994; 23: 103-114.
3. Chen J, Fujii K, Zhang L, Roberts T, Fu H. Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism. Proc Natl Acad Sci USA 2001; 98: 7783-7788. (Pubitemid 32642638)
4. Choy JC, Granville DJ, Hunt DW, McManus BM. Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis. J Mol Cell Cardiol 2001; 33: 1673-1690. (Pubitemid 32844225)
5. Madge LA, Pober JS. TNF signaling in vascular endothelial cells. Exp Mol Pathol 2001; 70: 317-325. (Pubitemid 32607204)
6. Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 1998; 281: 1305-1308. (Pubitemid 28406815)
7. Chen G, Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science 2002; 296: 1634-1635. (Pubitemid 34579145)
8. Ichijo H. Molecular mechanisms for cell life and cell death. Kokubyo Gakkai Zasshi 1998; 65: 155-163.
9. Matsuzawa A, Ichijo H. Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1. J Biochem (Tokyo) 2001; 130: 1-8. (Pubitemid 32674557)
10. Takeda K, Matsuzawa A, Nishitoh H, Ichijo H. Roles of MAPKKK ASK1 in stress-induced cell death. Cell Struct Funct 2003; 28: 23-29. (Pubitemid 36443126)
11. Dasgupta P, Betts V, Rastogi S, Joshi B, Morris M, Brennan B et al. Direct binding of apoptosis signal-regulating kinase 1 to retinoblastoma protein: novel links between apoptotic signaling and cell cycle machinery. J Biol Chem 2004; 279: 38762-38769. (Pubitemid 39296034)
12. Harbour JW, Dean DC. Rb function in cell-cycle regulation and apoptosis. Nat Cell Biol 2000; 2: E65-E67.
13. Liu DX, Nath N, Chellappan SP, Greene LA. Regulation of neuron survival and death by p130 and associated chromatin modifiers. Genes Dev 2005; 19: 719-732. (Pubitemid 40395083)
14. Dasgupta P, Sun J, Wang S, Fusaro G, Betts V, Padmanabhan J et al. Disruption of the Rb-Raf-1 interaction inhibits tumor growth and angiogenesis. Mol Cell Biol 2004; 24: 9527-9541. (Pubitemid 39391689)
15. Harbour JW, Dean DC. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev 2000; 14: 2393-2409.
16. Phillips AC, Vousden KH. E2F-1 induced apoptosis. Apoptosis 2001; 6: 173-182. (Pubitemid 32423726)
17. Tonini T, Hillson C, Claudio PP. Interview with the retinoblastoma family members: do they help each other? J Cell Physiol 2002; 192: 138-150. (Pubitemid 34747782)
18. Kinkade R, Rizwani W, Chellappan S. E2F transcription factors in cell proliferation, apoptosis, senescence and cancer. In: Yoshida K (ed). Control of Cellular Physiology by Transcription Factors E2F. Research Signpost Press: Trivandrum, India, 2007.
19. Lopez-Marure R, Bernal AE, Zentella A. Interference with c-myc expression and RB phosphorylation during TNF-mediated growth arrest in human endothelial cells. Biochem Biophys Res Commun 1997; 236: 819-824. (Pubitemid 27384716)
20. Goukassian DA, Kishore R, Krasinski K, Dolan C, Luedemann C, Yoon YS et al. Engineering the response to vascular injury: divergent effects of deregulated E2F1 expression on vascular smooth muscle cells and endothelial cells result in endothelial recovery and inhibition of neointimal growth. Circ Res 2003; 93: 162-169. (Pubitemid 36919704)
21. Kishore R, Luedemann C, Bord E, Goukassian D, Losordo DW. Tumor necrosis factormediated E2F1 suppression in endothelial cells: differential requirement of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signal transduction pathways. Circ Res 2003; 93: 932-940. (Pubitemid 37433231)
22. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999; 340: 115-126.
23. Tanaka H, Nishikawa O, Yukawa S, Yoshimoto M, Nishide I. Effects of hemodialysis membrane on serum lipid profile of maintenance hemodialysis patients]. Nippon Jinzo Gakkai Shi 1999; 41: 1-7.
24. Wang Z, Rao PJ, Castresana MR, Newman WH. TNF-alpha induces proliferation or apoptosis in human saphenous vein smooth muscle cells depending on phenotype. Am J Physiol Heart Circ Physiol 2005; 288: H293-H301. (Pubitemid 40023859)
25. Selzman CH, Shames BD, Reznikov LL, Miller SA, Meng X, Barton HA et al. Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation. Circ Res 1999; 84: 867-875. (Pubitemid 29196730)
26. Geng YJ, Azuma T, Tang JX, Hartwig JH, Muszynski M, Wu Q et al. Caspase-3-induced gelsolin fragmentation contributes to actin cytoskeletal collapse, nucleolysis, and apoptosis of vascular smooth muscle cells exposed to proinflammatory cytokines. Eur J Cell Biol 1998; 77: 294-302. (Pubitemid 29017163)
27. Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997; 275: 90-94. (Pubitemid 27020316)
28. Murray-Zmijewski F, Lane DP, Bourdon JC. p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress. Cell Death Differ 2006; 13: 962-972.
29. Lissy NA, Davis PK, Irwin M, Kaelin WG, Dowdy SF. A common E2F-1 and p73 pathway mediates cell death induced by TCR activation. Nature 2000; 407: 642-645.
30. Pediconi N, Ianari A, Costanzo A, Belloni L, Gallo R, Cimino L et al. Differential regulation of E2F1 apoptotic target genes in response to DNA damage. Nat Cell Biol 2003; 5: 552-558. (Pubitemid 36781090)
31. Vallieres K, Petitclerc E, Laroche G. On the ability of imatinib mesylate to inhibit smooth muscle cell proliferation without delaying endothelialization: an in vitro study. Vascul Pharmacol 2009; 51: 50-56.
32. Schwartz SM, Virmani R, Rosenfeld ME. The good smooth muscle cells in atherosclerosis. Curr Atheroscler Rep 2000; 2: 422-429.
33. Introna M, Mantovani A. Early activation signals in endothelial cells. Stimulation by cytokines. Arterioscler Thromb Vasc Biol 1997; 17: 423-428. (Pubitemid 27133130)
34. Chau BN, Chen TT, Wan YY, DeGregori J, Wang JY. Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation. Mol Cell Biol 2004; 24: 4438-4447. (Pubitemid 41071013)
35. Goetze S, Kintscher U, Kaneshiro K, Meehan WP, Collins A, Fleck E et al. TNFalpha induces expression of transcription factors c-fos, Egr-1, and Ets-1 in vascular lesions through extracellular signal-regulated kinases 1/2. Atherosclerosis 2001; 159: 93-101. (Pubitemid 33016626)
36. Wang S, Nath N, Minden A, Chellappan S. Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases. Embo J 1999; 18: 1559-1570. (Pubitemid 29127069)
37. Lau LM, Nugent JK, Zhao X, Irwin MS. HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function. Oncogene 2008; 27: 997-1003. (Pubitemid 351225385)
38. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408. (Pubitemid 34164012)
39. Horvilleur E, Bauer M, Goldschneider D, Mergui X, de la Motte A, Benard J et al. p73alpha isoforms drive opposite transcriptional and post-transcriptional regulation of MYCN expression in neuroblastoma cells. Nucleic Acids Res 2008; 36: 4222-4232.
40. Derossi D, Joliot AH, Chassaing G, Prochiantz A. The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem 1994; 269: 10444-10450. (Pubitemid 24198241)