Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 2, 2012, Pages 290-301

  Krause, Kerstin ^a   Boisnard, Alexandra ^a   Ihling, Christian ^b   Ludgate, Marian ^c   Eszlinger, Markus ^a   Krohn, Knut ^a   Sinz, Andrea ^b   Fuhrer, Dagmar ^d  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

2D DIGE proteomics; cAMP signaling; Mass spectrometry; Thyroid hormone stimulating receptor (TSHR); Toxic thyroid nodules

Indexed keywords

CYCLIC AMP; INOSITOL PHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAB PROTEIN; THYROTROPIN RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME PHOSPHORYLATION; FUNCTIONAL PROTEOMICS; GAIN OF FUNCTION MUTATION; GENETIC TRANSCRIPTION; INTERNALIZATION; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; THYROID CELL; THYROID GLAND; WESTERN BLOTTING;

ANIMALS; CYCLIC AMP; HUMANS; MAP KINASE SIGNALING SYSTEM; MUTATION; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEOMICS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, THYROTROPIN; SIGNAL TRANSDUCTION; THYROID GLAND; TRANSCRIPTION, GENETIC;

RATTUS;

EID: 84855595934     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2011.10.024     Document Type: Article

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