Radiation proctitis: Current strategies in management

Gastroenterology Research and Practice

Volumn , Issue , 2011, Pages

  Do, Nhue L ^a   Nagle, Deborah ^a   Poylin, Vitaliy Y ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; AMIFOSTINE; ANTIBIOTIC AGENT; ANTIDIARRHEAL AGENT; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; ANTIRETROVIRUS AGENT; ASCORBIC ACID; BETAMETHASONE; BUTYRIC ACID; FORMALDEHYDE; HYDROCORTISONE; MESALAZINE; METRONIDAZOLE; MISOPROSTOL; NONSTEROID ANTIINFLAMMATORY AGENT; OXO K993; PENTOSAN POLYSULFATE; PLACEBO; PREDNISOLONE; PREDNISONE; RETINOL; SALAZOSULFAPYRIDINE; SHORT CHAIN FATTY ACID; STEROID; SUCRALFATE; TETRACHLORODECAOXIDE; UNCLASSIFIED DRUG;

ABLATION THERAPY; ACQUIRED IMMUNE DEFICIENCY SYNDROME; ACUTE RADIATION PROCTITIS; ANTIBIOTIC THERAPY; ARGON PLASMA COAGULATION; BRACHYTHERAPY; CANCER RADIOTHERAPY; CAUTERIZATION; CHRONIC RADIATION PROCTITIS; CLINICAL TRIAL (TOPIC); COLON BIOPSY; COLON FISTULA; COLON PERFORATION; COLONOSCOPY; DIARRHEA; DISEASE SEVERITY; DRUG ABSORPTION; DRUG EFFICACY; DRUG MECHANISM; DRUG METABOLISM; ELECTROCOAGULATION; ENDOSCOPIC COAGULATION; ENTERITIS; EXTERNAL BEAM RADIOTHERAPY; HUMAN; HYPERBARIC OXYGEN; INFLAMMATION; INVASIVE PROCEDURE; OXIDATIVE STRESS; POSTOPERATIVE HEMORRHAGE; PREVENTIVE MEDICINE; PROCTITIS; PROCTOCOLECTOMY; PROSPECTIVE STUDY; RADIATION DOSE DISTRIBUTION; RADIATION HAZARD; RADIATION INJURY; RECTUM SURGERY; REHYDRATION; REVIEW; SIGMOIDOSCOPY; STEROID THERAPY; SURGICAL TECHNIQUE; TREATMENT INDICATION; TREATMENT OUTCOME; TREATMENT RESPONSE; YAG LASER;

EID: 84855590843     PISSN: 16876121     EISSN: 1687630X     Source Type: Journal    
DOI: 10.1155/2011/917941     Document Type: Review

References (71)

1. Xiao M., Whitnall M. H., Pharmacological countermeasures for the acute radiation syndrome Current Molecular Pharmacology 2009 2 1 122 133
2. Denton A., Forbes A., Andreyev J., Maher E. J., Non surgical interventions for late radiation proctitis in patients who have received radical radiotherapy to the pelvis Cochrane Database of Systematic Reviews 2002 1
3. Terasawa T., Dvorak T., Ip S., Raman G., Lau J., Trikalinos T. A., Systematic review: charged-particle radiation therapy for cancer Annals of Internal Medicine 2009 151 8 556 565
4. Melian E., Mageras G. S., Fuks Z., Leibel S. A., Niehaus A., Lorant H., Zelefsky M., Baldwin B., Kutcher G. J., Variation in prostate position quantitation and implications for three- dimensional conformal treatment planning International Journal of Radiation Oncology Biology Physics 1997 38 1 73 81 (Pubitemid 27270945)
5. Fraass B. A., Kessler M. L., McShan D. L., Marsh L. H., Watson B. A., Dusseau W. J., Eisbruch A., Sandler H. M., Lichter A. S., Optimization and clinical use of multisegment intensity-modulated radiation therapy for high-dose conformal therapy Seminars in Radiation Oncology 1999 9 1 60 77 (Pubitemid 29096024)
6. Shah S. A., Cima R. R., Benoit E., Breen E. L., Bleday R., Rectal complications after prostate brachytherapy Diseases of the Colon and Rectum 2004 47 9 1487 1492 (Pubitemid 39295876)
7. Lesperance R. N., Kjorstadt R. J., Halligan J. B., Steele S. R., Colorectal complications of external beam radiation versus brachytherapy for prostate cancer American Journal of Surgery 2008 195 5 616 620 (Pubitemid 351522205)
8. Schultheiss T. E., Lee W. R., Hunt M. A., Hanlon A. L., Peter R. S., Hanks G. E., Late GI and GU complications in the treatment of prostate cancer International Journal of Radiation Oncology Biology Physics 1997 37 1 3 11 (Pubitemid 27090129)
9. Coia L. R., Late effects of radiation therapy on the gastrointestinal tract International Journal of Radiation Oncology Biology Physics 1995 31 5 1213 1236
10. Beard C. J., Propert K. J., Rieker P. P., Clark J. A., Kaplan I., Kantoff P. W., Talcott J. A., Complications after treatment with external-beam irradiation in early- stage prostate cancer patients: a prospective multiinstitutional outcomes study Journal of Clinical Oncology 1997 15 1 223 229 (Pubitemid 27020577)
11. Pilepich M. V., Krall J. M., Sause W. T., Correlation of radiotherapeutic parameters and treatment related morbidity in carcinoma of the prostateanalysis of RTOG study 75-06 International Journal of Radiation Oncology Biology Physics 1987 13 3 351 357 (Pubitemid 17053947)
12. Zelefsky M. J., Fuks Z., Hunt M., Yamada Y., Marion C., Ling C. C., Amols H., Venkatraman E. S., Leibel S. A., High-dose intensity modulated radiation therapy for prostate cancer: early toxicity and biochemical outcome in 772 patients International Journal of Radiation Oncology Biology Physics 2002 53 5 1111 1116 (Pubitemid 34787844)
13. Zelefsky M. J., Levin E. J., Hunt M., Yamada Y., Shippy A. M., Jackson A., Amols H. I., Incidence of late rectal and urinary toxicities after three-dimensional conformal radiotherapy and intensity-modulated radiotherapy for localized prostate cancer International Journal of Radiation Oncology Biology Physics 2008 70 4 1124 1129 (Pubitemid 351296130)
14. Zietman A. L., Bae K., Slater J. D., Shipley W. U., Efstathiou J. A., Coen J. J., Bush D. A., Lunt M., Spiegel D. Y., Skowronski R., Jabola B. R., Rossi C. J., Randomized trial comparing conventional-dose with high-dose conformal radiation therapy in early-stage adenocarcinoma of the prostate: long-term results from proton radiation oncology group/american college of radiology 95-09 Journal of Clinical Oncology 2010 28 7 1106 1111
15. Zeitlin S. I., Sherman J., Raboy A., Lederman G., Albert P., High dose combination radiotherapy for the treatment of localized prostate cancer Journal of Urology 1998 160 1 91 96 (Pubitemid 29479422)
16. Denton A. S., Andreyev H. J. N., Forbes A., Maher E. J., Systematic review for non-surgical interventions for the management of late radiation proctitis British Journal of Cancer 2002 87 2 134 143
17. Cotti G., Seid V., Araujo S., Souza A. H., Kiss D. R., Habr-Gama A., Conservative therapies for hemorrhagic radiation proctitis: a review Revista do Hospital das Clnicas. 2003 58 5 284 292
18. Tagkalidis P. P., Tjandra J. J., Chronic radiation proctitis ANZ Journal of Surgery 2001 71 4 230 237
19. Kennedy M., Bruninga K., Mutlu E. A., Losurdo J., Choudhary S., Keshavarzian A., Successful and sustained treatment of chronic radiation proctitis with antioxidant vitamins E and C American Journal of Gastroenterology 2001 96 4 1080 1084 (Pubitemid 32319140)
20. Willett C. G., Ooi C. J., Zietman A. L., Menon V., Goldberg S., Sands B. E., Podolsky D. K., Acute and late toxicity of patients with inflammatory bowel disease undergoing irradiation for abdominal and pelvic neoplasms International Journal of Radiation Oncology Biology Physics 2000 46 4 995 998 (Pubitemid 30114413)
21. Phan J., Swanson D. A., Levy L. B., Kudchadker R. J., Bruno T. L., Frank S. J., Late rectal complications after prostate brachytherapy for localized prostate cancer Cancer 2009 115 9 1827 1839
22. Hoffman R., Welton M. L., Klencke B., Weinberg V., Krieg R., The significance of pretreatment CD4 count on the outcome and treatment tolerance of HIV-positive patients with anal cancer International Journal of Radiation Oncology Biology Physics 1999 44 1 127 131 (Pubitemid 29186199)
23. Housri N., Yarchoan R., Kaushal A., Radiotherapy for patients with the human immunodeficiency virus: are special precautions necessary? Cancer 2010 116 2 273 283
24. Kertesz T., Herrmann M. K.A., Zapf A., Christiansen H., Hermann R. M., Pradier O., Schmidberger H., Hess C. F., Hille A., Effect of a prostaglandingiven rectally for prevention of radiation-induced acute proctitison late rectal toxicity: results of a phase III randomized, placebo-controlled, double-blind study Strahlentherapie und Onkologie 2009 185 9 596 602
25. Kneebone A., Mameghan H., Bolin T., Berry M., Turner S., Kearsley J., Graham P., Fisher R., Delaney G., Effect of oral sucralfate on late rectal injury associated with radiotherapy for prostate cancer: a double-blind, randomized trial International Journal of Radiation Oncology Biology Physics 2004 60 4 1088 1097 (Pubitemid 39440793)
26. O'Brien P. C., Franklin C. I., Poulsen M. G., Joseph D. J., Spry N. S., Denham J. W., Acute symptoms, not rectally administered sucralfate, predict for late radiation proctitis: longer term follow-up of a phase III trialTrans-Tasman Radiation Oncology Group International Journal of Radiation Oncology Biology Physics 2002 54 2 442 449 (Pubitemid 35286810)
27. Hovdenak N., Srbye H., Dahl O., Sucralfate does not ameliorate acute radiation proctitis: randomised study and meta-analysis Clinical Oncology 2005 17 6 485 491 (Pubitemid 41136146)
28. Liu T., Liu Y., He S., Zhang Z., Kligerman M. M., Use of radiation with or without WR-2721 in advanced rectal cancer Cancer 1992 69 11 2820 2825
29. Athanassiou H., Antonadou D., Coliarakis N., Kouveli A., Synodinou M., Paraskevaidis M., Sarris G., Georgakopoulos G. R., Panousaki K., Karageorgis P., Throuvalas N., Protective effect of amifostine during fractionated radiotherapy in patients with pelvic carcinomas: results of a randomized trial International Journal of Radiation Oncology Biology Physics 2003 56 4 1154 1160 (Pubitemid 36794050)
30. Keefe D. M., Schubert M. M., Elting L. S., Sonis S. T., Epstein J. B., Raber-Durlacher J. E., Migliorati C. A., McGuire D. B., Hutchins R. D., Peterson D. E., Updated clinical practice guidelines for the prevention and treatment of mucositis Cancer 2007 109 5 820 831 (Pubitemid 46335677)
31. Peppercorn M. A., Sulfasalazine. Pharmacology, clinical use toxicity, and related new drug development Annals of Internal Medicine 1984 101 3 377 386 (Pubitemid 14033791)
32. Rains C. P., Noble S., Faulds D., Sulfasalazine: a review of its pharmacological properties and therapeutic efficacy in the treatment of rheumatoid arthritis Drugs 1995 50 1 137 156
33. Klotz U., Maier K., Fischer C., Heinkel K., Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease New England Journal of Medicine 1980 303 26 1499 1502 (Pubitemid 11178978)
34. Kochhar R., Patel F., Scharma S. C., Ayyagari S., Aggarwal R., Goenka M. K., Gupta B. D., Mehta S. K., Radiation-induced proctosigmoiditis: prospective, randomized, double-blind controlled trial of oral sulfasalazine plus rectal steroids versus rectal sucralfate Digestive Diseases and Sciences 1991 36 1 103 107
35. Schwiebert L. A., Beck L. A., Stellato C., Bickel C. A., Bochner B. S., Schleimer R. P., Glucocorticosteroid inhibition of cytokine production: relevance to antiallergic actions Journal of Allergy and Clinical Immunology 1996 97 1 143 152 (Pubitemid 26049495)
36. Freeman C. D., Klutman N. E., Lamp K. C., Metronidazole. A therapeutic review and update Drugs 1997 54 5 679 708 (Pubitemid 27480240)
37. Cavcic J., Turcic J., Martinac P., Jelincic Z., Zupancic B., Panijan-Pezerovic R., Unusic J., Metronidazole in the treatment of chronic radiation proctitis: clinical trial Croatian Medical Journal 2000 41 3 314 318
38. Veerasarn V., Boonnuch W., Kakanaporn C., A phase II study to evaluate WF10 in patients with late hemorrhagic radiation cystitis and proctitis Gynecologic Oncology 2006 100 1 179 184 (Pubitemid 41815070)
39. McGraw B. F., Caldwell E. G., Sucralfate Drug Intelligence and Clinical Pharmacy 1981 15 7-8 578 580 (Pubitemid 11000463)
40. Nagashima R., Mechanisms of action of sucralfate Journal of Clinical Gastroenterology 1981 3 supplement 2 117 127 (Pubitemid 12134289)
41. Sanguineti G., Franzone P., Marcenaro M., Foppiano F., Vitale V., Sucralfate versus mesalazine versus hydrocortisone in the prevention of acute radiation proctitis during conformal radiotherapy for prostate carcinoma: a randomized study Strahlentherapie und Onkologie 2003 179 7 464 470 (Pubitemid 36735775)
42. Grigsby P. W., Pilepich M. V., Parsons C. L., Preliminary results of a phase I/II study of sodium pentosanpolysulfate in the treatment of chronic radiation-induced proctitis American Journal of Clinical Oncology 1990 13 1 28 31 (Pubitemid 20114554)
43. Darcy-Vrillon B., Cherbuy C., Morel M. T., Durand M., Duée P. H., Short chain fatty acid and glucose metabolism in isolated pig colonocytes: modulation by NH 4 + Molecular and Cellular Biochemistry 1996 156 2 145 151 (Pubitemid 26108896)
44. Duée P. H., Darcy-Vrillon B., Blachier F., Morel M. T., Fuel selection in intestinal cells Proceedings of the Nutrition Society 1995 54 1 83 94
45. Aalkjaer C., Short chained fatty acids and the colon: how do they cause vasodilatation? Journal of Physiology 2002 538 3 674 (Pubitemid 35190063)
46. Talley N. A., Chen F., King D., Jones M., Talley N. J., Short-chain fatty acids in the treatment of radiation proctitis: a randomized, double-blind, placebo-controlled, cross-over pilot trial Diseases of the Colon and Rectum 1997 40 9 1046 1050 (Pubitemid 27377581)
47. Pinto A., Fidalgo P., Cravo M., Mides J., Chaves P., Rosa J., Dos Anjos Brito M., Nobre Leito C., Short chain fatty acids are effective in short-term treatment of chronic radiation proctitis: randomized, double-blind, controlled trial Diseases of the Colon and Rectum 1999 42 6 788 796 (Pubitemid 29279432)
48. Al-Sabbagh R., Sinicrope F. A., Sellin J. H., Shen Y., Roubein L., Evaluation of short-chain fatty acid enemas: treatment of radiation proctitis Diseases of the Colon Rectum 1997 40 9 1046 1050
49. Feldmeier J. J., Hampson N. B., A systematic review of the literature reporting the application of hyperbaric oxygen prevention and treatment of delayed radiation injuries: an evidence based approach Undersea and Hyperbaric Medicine 2002 29 1 4 30
50. Marx R. E., A new concept in the treatment of osteoradionecrosis Journal of Oral and Maxillofacial Surgery 1983 41 6 351 357 (Pubitemid 13054600)
51. Bennett M. H., Feldmeier J., Hampson N., Smee R., Milross C., Hyperbaric oxygen therapy for late radiation tissue injury Cochrane Database of Systematic Reviews 2005 3
52. Clarke R. E., Tenorio L. M. C., Hussey J. R., Toklu A. S., Cone D. L., Hinojosa J. G., Desai S. P., Dominguez Parra L., Rodrigues S. D., Long R. J., Walker M. B., Hyperbaric oxygen treatment of chronic refractory radiation proctitis: a randomized and controlled double-blind crossover trial with long-term follow-up International Journal of Radiation Oncology Biology Physics 2008 72 1 134 143
53. Ehrenpreis E. D., Jani A., Levitsky J., Ahn J., Hong J., A prospective, randomized, double-blind, placebo-controlled trial of retinol palmitate (vitamin A) for symptomatic chronic radiation proctopathy Diseases of the Colon and Rectum 2005 48 1 1 8
54. Patel P., Subhas G., Gupta A., Chang Y. J., Mittal V. K., McKendrick A., Oral vitamin A enhances the effectiveness of formalin 8 in treating chronic hemorrhagic radiation proctopathy Diseases of the Colon and Rectum 2009 52 9 1605 1609
55. Haas E. M., Bailey H. R., Farragher I., Application of 10 percent formalin for the treatment of radiation-induced hemorrhagic proctitis Diseases of the Colon and Rectum 2007 50 2 213 217 (Pubitemid 46227218)
56. Parikh S., Hughes C., Salvati E. P., Eisenstat T., Oliver G., Chinn B., Notaro J., Treatment of hemorrhagic radiation proctitis with 4 percent formalin Diseases of the Colon and Rectum 2003 46 5 596 600 (Pubitemid 36576415)
57. Counter S. F., Froese D. P., Hart M. J., Prospective evaluation of formalin therapy for radiation proctitis American Journal of Surgery 1999 177 5 396 398 (Pubitemid 29252809)
58. Mathai V., Seow-Choen F., Endoluminal formalin therapy for haemorrhagic radiation proctitis British Journal of Surgery 1995 82 2 190
59. Tjandra J. J., Sengupta S., Argon plasma coagulation is an effective treatment for refractory hemorrhagic radiation proctitis Diseases of the Colon and Rectum 2001 44 12 1759 1765 (Pubitemid 34031431)
60. Fantin A. C., Binek J., Suter W. R., Meyenberger C., Argon beam coagulation for treatment of symptomatic radiation-induced proctitis Gastrointestinal Endoscopy 1999 49 4 515 518 (Pubitemid 29217344)
61. Silva R. A., Correia A. J., Dias L. M., Viana H. L., Viana R. L., Argon plasma coagulation therapy for hemorrhagic radiation proctosigmoiditis Gastrointestinal Endoscopy 1999 50 2 221 224 (Pubitemid 29380369)
62. Swan M. P., Moore G. T. C., Sievert W., Devonshire D. A., Efficacy and safety of single-session argon plasma coagulation in the management of chronic radiation proctitis Gastrointestinal Endoscopy 2010 72 1 150 154
63. Higuera C. S., Arribas M. I. M., Gmez S. J. R., Villoria A. P., Moreno J. M., Gonzlez A. B., Efficacy and safety of argon plasma coagulation for the treatment of hemorrhagic radiation proctitis Revista Espanola de Enfermedades Digestivas 2004 96 11 758 764
64. Alexander T. J., Dwyer R. M., Endoscopic Nd:YAG laser treatment of severe radiation injury of the lower gastrointestinal tract: long-term follow-up Gastrointestinal Endoscopy 1988 34 5 407 411
65. Ventrucci M., Di Simone M. P., Giulietti P., De Luca G., Efficacy and safety of Nd:YAG laser for the treatment of bleeding from radiation proctocolitis Digestive and Liver Disease 2001 33 3 230 233 (Pubitemid 32452055)
66. Jao S. W., Beart R. W., Gunderson L. L., Surgical treatment of radiation injuries of the colon and rectum American Journal of Surgery 1986 151 2 272 277 (Pubitemid 16107315)
67. Ayerdi J., Moinuddeen K., Loving A., Wiseman J., Deshmukh N., Diverting loop colostomy for the treatment of refractory gastrointestinal bleeding secondary to radiation proctitis Military Medicine 2001 166 12 1091 1093 (Pubitemid 34015291)
68. Pricolo V. E., Shellito P. C., Surgery for radiation injury to the large intestine: variables influencing outcome Diseases of the Colon and Rectum 1994 37 7 675 684 (Pubitemid 24217735)
69. Anseline P. F., Lavery I. C., Fazio V. W., Radiation injury of the rectum. Evaluation of surgical treatment Annals of Surgery 1981 194 6 716 724 (Pubitemid 12248412)
70. Lucarotti M. E., Mountford R. A., Bartolo D. C. C., Surgical management of intestinal radiation injury Diseases of the Colon and Rectum 1991 34 10 865 869
71. Nieder A. M., Porter M. P., Soloway M. S., Radiation therapy for prostate cancer increases subsequent risk of bladder and rectal cancer: a population based cohort study Journal of Urology 2008 180 5 2005 2010