Does varicocelectomy improve gonadal function in men with hypogonadism and infertility? Analysis of a prospective study

International Journal of Endocrinology

Volumn 2011, Issue , 2011, Pages

  Sathya Srini, Vasan ^a   Belur Veerachari, Srinivas ^a  

^a Ankur Health Care Private Limited   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FOLLITROPIN; LUTEINIZING HORMONE; PROLACTIN; TESTOSTERONE;

ADULT; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; ERECTILE DYSFUNCTION; FERTILIZATION IN VITRO; FOLLITROPIN BLOOD LEVEL; GONAD FUNCTION; HUMAN; HYPOGONADISM; INTRACYTOPLASMIC SPERM INJECTION; LUTEINIZING HORMONE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PROSPECTIVE STUDY; SEMEN ANALYSIS; SEXUAL COUNSELING; SPERMATOZOON COUNT; TESTIS SIZE; TESTOSTERONE BLOOD LEVEL; VARICOCELE; VARICOCELECTOMY;

EID: 84855572978     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2011/916380     Document Type: Article

References (43)

1. Cockett A. T. K., Takihara H., Cosentino M. J., The varicocele Fertility and Sterility 1984 41 1 5 11 (Pubitemid 14181875)
2. Valeri A., Mianné D., Merouze F., Bujan L., Altobelli A., Masson J., Scrotal temperature in 258 healthy men, randomly selected from a population of men aged 18 to 23 years old. Statistical analysis, epidemiologic observations, and measurement of the testicular diameters Progrs en Urologie 1993 3 3 444 452
3. Romeo C., Arrigo T., Impellizzeri P., Manganaro A., Antonuccio P., Di Pasquale G., Messina M. F., Marseglia L., Formica I., Zuccarello B., Altered serum inhibin b levels in adolescents with varicocele Journal of Pediatric Surgery 2007 42 2 390 394 (Pubitemid 46161565)
4. Camoglio F. S., Zampieri N., Corroppolo M., Chironi C., Dipaola G., Giacomello L., Ottolenghi A., Varicocele and retrograde adrenal metabolites flow: an experimental study on rats Urologia Internationalis 2004 73 4 337 342 (Pubitemid 39664307)
5. Weiss D. B., Rodriguez-Rigau L. J., Smith K. D., Steinberger E., Leydig cell function in oligospermic men with varicocele Journal of Urology 1978 120 4 427 430 (Pubitemid 9031103)
6. Della Morte E., Fortuna F. F., Gerevini G., Lania C., Grasso M., Evaluation of FSH and Leydig cells function in patients with varicocele Archivio Italiano di Urologia 2002 74 3 152 156
7. Cayan S., Kadioglu A., Orhan I., Kandirali E., Tefekli A., Tellaloglu S., The effect of microsurgical varicocelectomy on serum follicle stimulating hormone, testosterone and free testosterone levels in infertile men with varicocele British Journal of Urology International 1999 84 9 1046 1049
8. Su L. M., Goldstein M., Schlegel P. N., The effect of varicocelectomy on serum testosterone levels in infertile men with varicoceles Journal of Urology 1995 154 5 1752 1755
9. Hurtado de Catalfo G. E., Ranieri-Casilla A., Marra F. A., de Alaniz M. J. T., Marra C. A., Oxidative stress biomarkers and hormonal profile in human patients undergoing varicocelectomy International Journal of Andrology 2007 30 6 519 530 (Pubitemid 350132284)
10. Gat Y., Gornish M., Belenky A., Bachar G. N., Elevation of serum testosterone and free testosterone after embolization of the internal spermatic vein for the treatment of varicocele in infertile men Human Reproduction 2004 19 10 2303 2306 (Pubitemid 39406692)
11. Ozden C., Ozdal O. L., Bulut S., Guzel O., Koyuncu H. H., Memis A., Effect of varicocelectomy on serum inhibin B levels in infertile patients with varicocele Scandinavian Journal of Urology and Nephrology 2008 42 5 441 443
12. Zheng Y. Q., Gao X., Li Z. J., Yu Y. L., Zhang Z. G., Li W., Efficacy of bilateral and left varicocelectomy in infertile men with left clinical and right subclinical varicoceles: a comparative study Urology 2009 73 6 1236 1240
13. Rogers R. S., Graziottin T. M., Lin C. M., Kan Y. W., Lue T. F., Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats International Journal of Impotence Research 2003 15 1 26 37 (Pubitemid 36356356)
14. Meusburger S. M., Keast J. R., Testosterone and nerve growth factor have distinct but interacting effects on structure and neurotransmitter expression of adult pelvic ganglion cells in vitro Neuroscience 2001 108 2 331 340 (Pubitemid 33152973)
15. Baba K., Yajima M., Carrier S., Morgan D. M., Nunes L., Lue T. F., Iwamoto T., Delayed testosterone replacement restores nitric oxide synthase-containing nerve fibres and the erectile response in rat penis British Journal of Urology International 2000 85 7 953 958 (Pubitemid 30242806)
16. Seo S. I., Kim S. W., Paick J. S., The effects of androgen on penile reflex, erectile response to electrical stimulation and penile NOS activity in the rat Asian Journal of Andrology 1999 1 4 169 174
17. Lungg J. A., Rajfer J., Gonzalez- Cadavid N. F., Dihydrotestosteroneis the active androgen in the mainteinance of nitric oxide-mediated penile erection in the rat Endocrinology 1995 136 1495 1501
18. Traish A. M., Park K., Dhir V., Kim N. N., Moreland R. B., Goldstein I., Effects of castration and androgen replacement on erectile function in a rabbit model Endocrinology 1999 140 4 1861 1868 (Pubitemid 29149259)
19. World Health Organisation, Laboratory Manual for the Examination of Human Sperm and the Sperm- Cervical Mucus Interaction 1999 Cambridge, UK Cambridge University Press
20. Hussein A. F., The role of color Doppler ultrasound in prediction of the outcome of microsurgical subinguinal varicocelectomy Journal of Urology 2006 176 5 2141 2145 (Pubitemid 44633175)
21. Zini A., Fischer M. A., Bellack D., Noss M., Kamal K., Chow V., Mak V., Technical modification of microsurgical varicocelectomy can reduce operating time Urology 2006 67 4 803 806
22. Pasqualotto F. F., Lucon A. M., de Ges P. M., Sobreiro B. P., Hallak J., Pasqualotto E. B., Arap S., Relationship between the number of veins ligated in a varicocelectomy with testicular volume, hormonal levels and semen parameters outcome Journal of Assisted Reproduction and Genetics 2005 22 6 245 249 (Pubitemid 40864078)
23. Shiraishi K., Takihara H., Matsuyama H., Elevated scrotal temperature, but not varicocele grade, reflects testicular oxidative stress-mediated apoptosis World Journal of Urology 2010 28 3 359 364
24. Reorlu B., Kara C., ahin E., nsal A., The significance of age on success of surgery for patients with varicocele International Urology and Nephrology 2010 42 2 351 356
25. Rajfer J., Turner T. T., Rivera F., Howards S. S., Sikka S. C., Inhibition of testicular testosterone biosynthesis following experimental varicocele in rats Biology of Reproduction 1987 36 4 933 937
26. Ghosh P. K., York J. P., Changes in testicular testosterone and acid and alkaline phosphatase activity in testis and accessory sex organs after induction of varicocele in noble rats Journal of Surgical Research 1994 56 3 271 276 (Pubitemid 24100439)
27. Takeyama M., Honjoh M., Kodama M., Sakaguchi H., Koh E., Kondoh N., Fujioka H., Nakamura M., Namiki M., Okuyama A., Matsumoto K., Sonoda T., Testicular steroids in spermatic and peripheral veins after single injection of hCG in patients with varicocele Archives of Andrology 1990 24 2 207 213 (Pubitemid 20119107)
28. Fujisawa M., Hayashi A., Imanishi O., The significance of gonadotropin- releasing hormone test for predicting positive effects on Leydig cell function Fertility and Sterility 1994 61 779 782
29. Podesta M. L., Gottlieb S., Medel R., Ropelato G., Bergada C., Quesada E. M., Hormonal parameters and testicular volume in children and adolescents with unilateral varicocele: preoperative and postoperative findings Journal of Urology 1994 152 2 794 797 (Pubitemid 24235912)
30. Corona G., Maggi M., The role of testosterone in erectile dysfunction Nature Reviews Urology 2010 7 1 46 56
31. Younes A. K. H., Low plasma testosterone in varicocele patients with impotence and male infertility Archives of Andrology 2000 45 3 187 195
32. Comhaire F., Vermeulen A., Plasma testosterone in patients with varicocele and sexual inadequacy Journal of Clinical Endocrinology and Metabolism 1975 40 5 824 829
33. Lotti F., Corona G., Mancini M., Biagini C., Colpi G. M., Innocenti S. D., Filimberti E., Gacci M., Krausz C., Sforza A., Forti G., Mannucci E., Maggi M., The association between varicocele, premature ejaculation and prostatitis symptoms: possible mechanisms Journal of Sexual Medicine 2009 6 10 2878 2887
34. Wischmann T. H., Sexual disorders in infertile couples Journal of Sexual Medicine 2010 7 5 1868 1876
35. Millheiser L. S., Helmer A. E., Quintero R. B., Westphal L. M., Milki A. A., Lathi R. B., Is infertility a risk factor for female sexual dysfunction? A case-control study Fertility and Sterility 2010 94 6 2022 2025
36. Drosdzol A., Skrzypulec V., Quality of life and sexual functioning of Polish infertile couples European Journal of Contraception and Reproductive Health Care 2008 13 3 271 281
37. Foss S. D., Dahl A. A., Fertility and sexuality in young cancer survivors who have adult-onset malignancies Hematology/Oncology Clinics of North America 2008 22 2 291 303 (Pubitemid 351452095)
38. Smith J. F., Walsh T. J., Shindel A. W., Turek P. J., Wing H., Pasch L., Katz P. P., Adler N., Croughan M., Gregorich S., Millstein S. G., Nachtigall R., Showstack J., Sexual, marital, and social impact of a man's perceived infertility diagnosis Journal of Sexual Medicine 2009 6 9 2505 2515
39. Drosdzol A., Skrzypulec V., Evaluation of marital and sexual interactions of polish infertile couples Journal of Sexual Medicine 2009 6 12 3335 3346
40. Yeniyol C. O., Tuna A., Yener H., Zeyrek N., Tilki A., High ligation to treat pain in varicocele International Urology and Nephrology 2003 35 1 65 68 (Pubitemid 37351147)
41. Karademir K., enkul T., Baykal K., Ate F., Ieri C., Erden D., Evaluation of the role of varicocelectomy including external spermatic vein ligation in patients with scrotal pain International Journal of Urology 2005 12 5 484 488 (Pubitemid 41015158)
42. Chawla A., Kulkarni G., Kamal K., Zini A., Microsurgical varicocelectomy for recurrent or persistent varicoceles associated with orchalgia Urology 2005 66 5 1072 1074 (Pubitemid 41587163)
43. Peterson A. C., Lance R. S., Ruiz H. E., Outcomes of varicocele ligation done for pain Journal of Urology 1998 159 5 1565 1567 (Pubitemid 29117343)