The role of Ala231 and Trp227 in the substrate specificities of fungal 17β-hydroxysteroid dehydrogenase and trihydroxynaphthalene reductase: Steroids versus smaller substrates

Journal of Steroid Biochemistry and Molecular Biology

Volumn 129, Issue 1-2, 2012, Pages 92-98

  Švegelj, Mojca Brunskole ^a   Stojan, Jure ^a   Rižner, Tea Lanišnik ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

17 Hydroxysteroid dehydrogenase; 2,3 Dihydro 2,5 dihydroxy 4H benzopyran 4 one; 4 Estrene 17 ol 3 one; 4 Estrene 3,17 dione; 9,10 Phenanthrenequinone; Curvularia lunata (teleomorph: Cochliobolus lunatus); Trihydroxynaphthalene reductase

Indexed keywords

AMINO ACID; DOCKING PROTEIN; ESTR 4 ENE 3,17 DIONE; MUTANT PROTEIN; OXIDOREDUCTASE; PHENANTHRENEQUINONE; PROTEIN ALA231; PROTEIN TRP227; TESTOSTERONE 17BETA DEHYDROGENASE; TRIHYDROXYNAPHTHALENE REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CURVULARIA LUNATA; ENZYME SPECIFICITY; OXIDATION; SPECTROPHOTOMETRY; THIN LAYER CHROMATOGRAPHY; WILD TYPE;

17-HYDROXYSTEROID DEHYDROGENASES; ALANINE; AMINO ACID SEQUENCE; ASCOMYCOTA; BENZOPYRANS; CATALYTIC DOMAIN; ESTRENES; FUNGAL PROTEINS; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PHENANTHRENES; STEROIDS; SUBSTRATE SPECIFICITY; TRYPTOPHAN;

COCHLIOBOLUS LUNATUS; FUNGI;

EID: 84855564222     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2011.03.019     Document Type: Article

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