Synthesis of (+)-ambrisentan via chiral ketone-catalyzed asymmetric epoxidation

Journal of Organic Chemistry

Volumn 77, Issue 1, 2012, Pages 701-703

  Peng, Xianyou ^a   Li, Peijun ^a   Shi, Yian ^a,b  

^a INSTITUTE OF CHEMISTRY   (China)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC EPOXIDATION; CHIRAL EPOXIDES;

KETONES; ORGANIC COMPOUNDS;

SYNTHESIS (CHEMICAL);

2 [(4,6 DIMETHYLPYRIMIDIN 2 YL)OXY] 3 METHOXY 3,3 DIPHENYLPROPIONIC ACID ETHYL ESTER; 2 [(4,6 DIMETHYLPYRIMIDIN 2 YL)OXY] 3 METHOXY 3,3 DIPHENYLPROPIONIC ACID METHYL ESTER; 2 HYDROXY 3 METHOXY 3,3 DIPHENYLPROPIONIC ACID ETHYL ESTER; AMBRISENTAN; FRUCTOSE DERIVED DIACETATE KETONE; KETONE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC EPOXIDATION; CATALYST; DRUG PURIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; EPOXIDATION;

CATALYSIS; EPOXY COMPOUNDS; KETONES; MOLECULAR STRUCTURE; PHENYLPROPIONATES; PYRIDAZINES; STEREOISOMERISM;

EID: 84855554736     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo201927m     Document Type: Article

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