The neurology of decreased activity: Abulia

Reviews in Neurological Diseases

Volumn 8, Issue 3-4, 2011, Pages

  Ghoshal, Shivani ^a   Gokhale, Sankalp ^b   Rebovich, Gail ^b   Caplan, Louis R ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Abulia; Akinesia; Apathy; Caudate nucleus; Delirium; Frontal lobe; Substantia nigra; Thalamus

Indexed keywords

BROMOCRIPTINE; CARBIDOPA PLUS LEVODOPA; CENTRAL STIMULANT AGENT; CHOLINESTERASE INHIBITOR; DONEPEZIL; DOPAMINE RECEPTOR STIMULATING AGENT; FLUOXETINE; GALANTAMINE; LISURIDE; METHYLPHENIDATE; NEFIRACETAM; PERGOLIDE;

ABULIA; AFFECT; AGITATION; ANTERIOR CINGULATE; ASTROCYTOMA; BASAL GANGLION; BEHAVIOR CONTROL; BRAIN DAMAGE; BRAIN EMBOLISM; CAPSULA INTERNA; CAUDATE NUCLEUS; ELECTROENCEPHALOGRAM; EXECUTIVE FUNCTION; FACIAL EXPRESSION; FRONTAL LOBE; GLOBUS PALLIDUS; HEMIPARESIS; HUMAN; MEMORY DISORDER; MUTISM; NERVE CELL MEMBRANE POTENTIAL; NEUROLOGIC DISEASE; NEUROTRANSMISSION; ORTHOSTATIC HYPOTENSION; PUTAMEN; REVIEW; STROKE; SUBSTANTIA NIGRA; SUPERIOR CEREBELLAR PEDUNCLE; TRAUMATIC BRAIN INJURY; WORKING MEMORY;

AKINETIC MUTISM; ANIMALS; BRAIN; HUMANS; MOTOR ACTIVITY; NERVE NET; NERVOUS SYSTEM DISEASES;

EID: 84855536683     PISSN: 15452913     EISSN: None     Source Type: Journal    
DOI: 10.3909/rind0286     Document Type: Review

References (61)

1. Caplan LR. Delirium: a neurologist's view - the neurology of agitation and overactivity. Rev Neurol Dis. 2010;7:111-118.
2. Vijayaraghavan L, Krishnamoorthy ES, Brown RG, Trimble MR. Abulia: a Delphi survey of British neurologists and psychiatrists. Mov Disord. 2002;17:1052-1057. (Pubitemid 36041014)
3. Ferro J, Verdelho A. Neurobehavioral aspects of deep hemisphere strokes. In: Caplan LR, Van Gijn J, eds. Stroke Syndromes, 3rd ed. Cambridge, UK: Cambridge University Press. In press.
4. Auerbach S. Beitrag zur diagnostik der Geschwulste des Stirnhirn. Dtsch Z Nervenheilkd. 1902;22:312-332.
5. Berrios GE, Gili M. Abulia and impulsiveness revisited: a conceptual history. Acta Psychiatr Scand. 1995;92:161-167.
6. Fisher CM. Abulia minor versus agitated behavior. Clin Neurosurg. 1983;31:9-31.
7. Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci. 1986;9:357-381. (Pubitemid 16055790)
8. Percheron G, Filion M. Parallel processing in the basal ganglia: up to a point. Trends Neurosci. 1991;14:55-59.
9. McFarland NR, Haber S. Thalamic relay nuclei of the basal ganglia form both reciprocal and nonreciprocal cortical connections, linking multiple frontal cortical areas. J Neurosci. 2002;22:8117-8132. (Pubitemid 35379118)
10. Barbas H. Connections underlying the synthesis of cognition, memory, and emotion in primate prefrontal cortices. Brain Res Bull. 2000;52:319-330. (Pubitemid 30462201)
11. Grunsfeld AA, Login IS. Abulia following penetrating brain injury during endoscopic sinus surgery with disruption of the anterior cingulate circuit: case report. BMC Neurol. 2006;6:4.
12. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 26-1990. A 68-year-old man with a right hemiparesis, abulia, and multiple intracerebral hemorrhages. N Engl J Med. 1990;322:1866-1878.
13. Förstl H, Sahakian B. A psychiatric presentation of abulia - three cases of left frontal lobe ischaemia and atrophy. J R Soc Med. 1991;84:89-91.
14. Muqit MM, Rakshi JS, Shakir RA, Larner AJ. Catatonia or abulia? A difficult differential diagnosis. Mov Disord. 2001;16:360-362. (Pubitemid 36049987)
15. Bhatia KP, Marsden CD. The behavioral and motor consequences of focal lesions of the basal ganglia in man. Brain. 1994;117:859-876. (Pubitemid 24281846)
16. Trillet M, Croisile B, Tourniaire D, Schott B. Perturbatons de l'activite motrice volontaire et lesions des noyaux caudes. Rev Neurol (Paris). 1990;146:338-344. (Pubitemid 20184791)
17. Kumral E, Evyapan D, Balkir K. Acute caudate vascular lesions. Stroke. 1999;30:100-108. (Pubitemid 29029449)
18. Mendez MF, Adams NL, Lewandowski KS. Neurobehavioral changes associated with caudate lesions. Neurology. 1989;39:349-354. (Pubitemid 19094724)
19. Caplan LR, Schmahmann JD, Kase CS, et al. Caudate infarcts. Arch Neurol. 1990;47:133-143. (Pubitemid 20058108)
20. Caplan LR, Helgason CM. Caudate infarcts. In: Donnan G, Norrving B, Bamford J, Bogousslavsky J, eds. Lacunar and Other Subcortical Infarctions. Oxford, UK: Oxford University Press; 1995:117-130.
21. Nagaratnam N, Fanella S, Gopinath S, Goodwin A. Prolonged abulia following putaminal hemorrhage. J Stroke Cerebrovasc Dis. 2001;10:92-93. (Pubitemid 32489099)
22. Jeong JH, Kwon JC, Chin J, et al. Globus pallidus lesions associated with high mountain climbing. J Korean Med Sci. 2002;17:861-863.
23. Adams NC, Lozsádi DA, Guillery RW. Complexities in the thalamocortical and corticothalamic pathways. Eur J Neurosci. 1997;9:204-209. (Pubitemid 27091100)
24. Pantoni L, Basile AM, Romanelli M, et al. Abulia and cognitive impairment in two patients with capsular genu infarct. Acta Neurol Scand. 2001;104:185-190. (Pubitemid 32831784)
25. Helgason C, Wilbur A, Weiss A, et al. Acute pseudobulbar mutism due to discrete bilateral capsular infarction in the territory of the anterior choroidal artery. Brain. 1988;111:507-524.
26. Madureira S, Guerreiro M, Ferro JM. A follow-up study of cognitive impairment due to inferior capsular genu infarction. J Neurol. 1999; 246:764-769. (Pubitemid 29467150)
27. Caplan LR. Posterior Circulation Disease. Clinical Findings, Diagnosis, and Management. Boston, MA: Blackwell Science; 1996.
28. Facon E, Steriade M, Werthein N. Hypersomnie prolongee engendree par des lesions bilaterales du systeme activateur medial: le syndrome thrombotique de la bifurcation du tronc basilaire. Rev Neurol (Paris). 1958;98:117-133.
29. Castaigne P, Buge A, Escourolle R, et al. Ramollissement pedonculaire median, tegmento-thalamique avec opthalmoplegie et hypersomnie. Rev Neurol. 1962;106:357-367.
30. Caplan LR. "Top of the basilar" syndrome. Neurology. 1980;30:72-79.
31. Mehler MF. The rostral basilar artery syndrome: diagnosis, etiology, prognosis. Neurology. 1989; 39:9-16. (Pubitemid 19033107)
32. Mehler MF. The neuro-ophthalmologic spectrum of the rostral basilar artery syndrome. Arch Neurol. 1988;45:966-971.
33. Segarra JM. Cerebral vascular disease and behavior. I. The syndrome of the mesencephalic artery (basilar artery bifurcation). Arch Neurol. 1970;22:408-418.
34. Guberman A, Stuss D. The syndrome of bilateral paramedian thalamic infarction. Neurology. 1983;33:540-546. (Pubitemid 13080439)
35. Stuss DT, Guberman A, Nelson R, Larochele S. The neuropsychology of paramedian thalamic infarction. Brain Cogn. 1988;8:348-378.
36. Bogousslavsky J, Regli F, Delaloye B, et al. Loss of psychic self-activation with bithalamic infarction. Neurobehavioural, CT, MRI, and SPECT correlates. Acta Neurol Scand. 1991;83:309-316.
37. Engelborghs S, Marien P, Pickut BA, et al. Loss of psychic self-activation after paramedian bithalamic infarction. Stroke. 2000;31:1762-1765. (Pubitemid 30437534)
38. Alexander MP. Chronic akinetic mutism after mesencephalic-diencephalic infarction: remediated with dopaminergic medications. Neurorehabil Neural Repair. 2001;15:151-156. (Pubitemid 34031135)
39. Bogousslavsky J, Regli F, Assal G. The syndrome of unilateral tuberothalamic artery territory infarction. Stroke. 1986;17:434-441. (Pubitemid 16085685)
40. Sandson TA, Daffner KR, Carvalho PA, Meslam MM. Frontal lobe dysfunction following infarction of the left-sided medial thalamus. Arch Neurol. 1991;48:1300-1303.
41. Lisovoski F, Koskas P, Dubard T, et al. Left tuberothalamic artery territory infarction: neuropsychological and MRI features. Eur Neurol. 1993;33:181-184. (Pubitemid 23100548)
42. Rousseaux M. Frontal lobe dysfunction in diencephalic and mesencephalic lesions. In: Leys D, Scheltens Ph, eds. Vascular Dementia. Dordrecht, Netherlands: ICG publications; 1994:71-85.
43. Kuwert T, Hennerici M, Langen KJ, et al. Regional cerebral glucose consumption measured by positron emission tomography in patients with unilateral thalamic infarction. Cerebrovasc Dis. 1991;1:327-336.
44. Szelies B, Herbolz K, Pawlik G, et al. Widespread functional effects of discrete thalamic infarction. Arch Neurol. 1991;48:178-182.
45. Kotila M, Hokkanen L, Laaksonen R, Valanne L. Long-term prognosis after left tuberothalamic infarction: a study of 7 cases. Cerebrovasc Dis. 1994;4:44-50.
46. Kaplan RF, Estol CJ, Damasio H, et al. Bilateral polar territory infarcts. Neurology. 1991;41 (suppl 1):329.
47. Lindvall O, Björklund A, Moore RY, Stenevi U. Mesencephalic dopamine neurons projecting to neocortex. Brain Res. 1974;81:325-331.
48. Botez MI, Barbaeau A. Role of subcortical structures, and particularly of the thalamus, in the mechanisms of speech and language: a review. Int J Neurol. 1971;8:300-320.
49. Hastak SM, Gorawara PS, Mishra NK. Abulia: no will, no way. J Assoc Physicians India. 2005;53:814-818. (Pubitemid 41365567)
50. Echiverri HC, Tattum WO, Merens TA, Coker SB. Akinetic mutism: pharmacologic probe of the dopaminergic mesencephalo-frontal activating system. Pediatr Neurol. 1988;4:228-230.
51. Crismon ML, Childs A, Wilcox RE, Barrow N. The effect of bromocriptine on speech dysfunction in patients with diffuse brain injury. Clin Neuropharmacol. 1988;11:462-466.
52. Albert ML, Bachman DL, Morgan A, Helm-Estabrooks N. Pharmacotherapy for aphasia. Neurology. 1988;38:877-879.
53. Fleet WS, Valenstein E, Watson RT, Heilman KM. Dopamine agonist therapy for neglect in humans. Neurology. 1987;37:1765-1770. (Pubitemid 17163720)
54. Barrett K. Treating organic abulia with bromocriptine and lisuride: four case studies. J Neurol Neurosurg Psychiatry. 1991;54:718-721.
55. Daly DD, Love JG. Akinetic mutism. Neurology. 1958;8:238-242.
56. Sawaguchi T, Goldman-Rakic PS. D1 dopamine receptors in prefrontal cortex: involvement in working memory. Science. 1991;251:947-950. (Pubitemid 21926192)
57. Watanabe MD, Martin EM, DeLeon OA. Successful methylphenidate treatment of apathy after subcortical infarcts. J Neuropsychiatry Clin Neurosci. 1995;7:502-504.
58. Whyte EM, Lenze EJ, Butters M, et al. An open-label pilot study of acetylcholinesterase inhibitors to promote functional recovery in elderly cognitively impaired stroke patients. Cerebrovasc Dis. 2008;26:317-321.
59. Robinson RG, Jorge RE, Clarence-Smith K. Double-blind randomized treatment of poststroke depression using nefiracetam. J Neuropsychiatry Clin Neurosci. 2008;20:178-184.
60. Jin J, Watabe S, Yamamoto T. Nefiracetam improves the impairment of local cerebral blood flow and glucose utilization after chronic focal cerebral ischemia in rats. Pharmacology. 2002;64:119-125. (Pubitemid 34136852)
61. Caplan LR, Ahmed I. Depression and neurological disease, their distinction and association. Gen Hosp Psychiatry. 1992;14:177-185.