Brazilin inhibits UVB-induced MMP-1/3 expressions and secretions by suppressing the NF-κB pathway in human dermal fibroblasts

European Journal of Pharmacology

Volumn 674, Issue 2-3, 2012, Pages 80-86

  Lee, Young Rae ^a   Noh, Eun Mi ^a   Han, Ji Hye ^a   Kim, Jeong Mi ^a   Hwang, Jin Ki ^a   Hwang, Bo Mi ^a   Chung, Eun Yong ^b   Kim, Byeong Soo ^c   Lee, Sung Ho ^c   Lee, Seung Jin ^d   Kim, Jong Suk ^a  

^a Chonbuk National University Medical School   (South Korea)

^b The Catholic University of Korea College of Medicine   (South Korea)

^c Kongju National University   (South Korea)

^d Ewha Womans University   (South Korea)

Author keywords

Brazilin; Matrix metalloproteinase; Nuclear factor B; Photoaging; Ultraviolet B

Indexed keywords

ANTIINFLAMMATORY AGENT; BRAZILIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERSTITIAL COLLAGENASE; REACTIVE OXYGEN METABOLITE; STROMELYSIN; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; FIBROBLAST; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ULTRAVIOLET B RADIATION;

BENZOPYRANS; DNA; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASES, SECRETED; NF-KAPPA B; RADIATION-PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SKIN; ULTRAVIOLET RAYS;

EID: 84855522302     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.10.016     Document Type: Article

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