Fungal periprosthetic hip and knee joint infections. Clinical experience with a 2-stage treatment protocol

Journal of Arthroplasty

Volumn 27, Issue 2, 2012, Pages 293-298

  Anagnostakos, Konstantinos ^a   Kelm, Jens ^a,b   Schmitt, Eduard ^a   Jung, Jochen ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b Chirurgisch orthopädisches Illingen ^*  (Germany)

Author keywords

2 stage treatment; Antibiotic loaded bone cement; Candida albicans; Fungal periprosthetic infection; Hip spacer; Knee spacer

Indexed keywords

ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; BONE CEMENT;

ADULT; AGED; ARTICLE; CANDIDA ALBICANS; CLINICAL ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; FEMALE; FOLLOW UP; FUNGAL PERIPROSTHETIC HIP JOINT INFECTION; FUNGAL PERIPROSTHETIC KNEE JOINT INFECTION; HIP ARTHROPLASTY; HIP PROSTHESIS; HUMAN; KNEE ARTHROPLASTY; KNEE PROSTHESIS; MALE; MYCOSIS; ORTHOPEDIC SURGERY; PRACTICE GUIDELINE; PROSTHESIS INFECTION; REINFECTION; TREATMENT DURATION;

AGED; ANTIFUNGAL AGENTS; ARTHROPLASTY, REPLACEMENT, HIP; ARTHROPLASTY, REPLACEMENT, KNEE; BONE CEMENTS; CANDIDA; CANDIDIASIS; COMBINED MODALITY THERAPY; DEBRIDEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOLLOW-UP STUDIES; HIP JOINT; HIP PROSTHESIS; HUMANS; KNEE JOINT; KNEE PROSTHESIS; MALE; MIDDLE AGED; MYCOSES; PROSTHESIS-RELATED INFECTIONS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84855520365     PISSN: 08835403     EISSN: 15328406     Source Type: Journal    
DOI: 10.1016/j.arth.2011.04.044     Document Type: Article

References (15)

1. Azzam K., Parvizi J., Jungkind D., et al. Microbiological, clinical, and surgical features of fungal prosthetic joint infections: a multi-institutional experience. J Bone Joint Surg Am 2009, 91:142.
2. Swieringa A.J., Goosen J.H., Jansman F.G., et al. In vivo pharmacokinetics of a gentamicin-loaded collagen sponge in acute periprosthetic infection: serum values in 19 patients. Acta Orthop 2008, 79:637.
3. Anagnostakos K., Fürst O.A., Kelm J. Antibiotic-impregnated PMMA hip spacers: current status. Acta Orthop 2006, 77:628.
4. Goss B., Lutton C., Weinrauch P., et al. Elution and mechanical properties of antifungal bone cement. J Arthroplasty 2007, 22:902.
5. Silverberg D., Kodali P., Dipersio J., et al. In vitro analysis of antifungal impregnated polymethylmethacrylate bone cement. Clin Orthop Relat Res 2002, 403:228.
6. McPherson E.J., Woodson C., Holtom P., et al. Periprosthetic total hip infection. Outcomes using a staging system. Clin Orthop Relat Res 2002, 403:8.
7. Marra F., Robbins G.M., Masri B.A., et al. Amphotericin B-loaded bone cement to treat osteomyelitis caused by Candida albicans. Can J Surg 2001, 44:383.
8. Anagnostakos K., Köhler D., Schmitt E., et al. The "glove"-technique: a modified method for femoral fixation of antibiotic-loaded hip spacers. Acta Orthop 2009, 80:386.
9. Dan M., Yossepowitch O., Hendel D., et al. Phialemonium curvatum arthritis of the knee following intra-articular injection of a corticosteroid. Med Mycol 2006, 44:571.
10. Bruce A.S., Kerry R.M., Norman P., et al. Fluconazole-impregnated beads in the management of fungal infection of prosthetic joints. J Bone Joint Surg Br 2001, 83:183.
11. Anagnostakos K., Kelm J. Enhancement of antibiotic elution from acrylic bone cement. J Biomed Mater Res B Appl Biomater 2009, 90:467.
12. Selmon G.P., Slater R.N., Shepperd J.A., et al. Successful 1-stage exchange total knee arthroplasty for fungal infection. J Arthroplasty 1998, 13:114.
13. Lerch K., Kalteis T., Schubert T., et al. Prosthetic joint infections with osteomyelitis due to Candida albicans. Mycoses 2003, 46:462.
14. Tunkel A.R., Thomas C.Y., Wispelwey B. Candida prosthetic arthritis: report of a case treated with fluconazole and review of the literature. Am J Med 1993, 94:100.
15. Cushing R.D., Fulgenzi W.R. Synovial fluid levels of fluconazole in a patient with Candida parapsilosis prosthetic joint infection who had an excellent clinical response. J Arthroplasty 1997, 12:950.