Nucleobindin 2 in human breast carcinoma as a potent prognostic factor

Cancer Science

Volumn 103, Issue 1, 2012, Pages 136-143

  Suzuki, Shiho ^a   Takagi, Kiyoshi ^a   Miki, Yasuhiro ^a   Onodera, Yoshiaki ^a   Akahira, Jun Ichi ^a   Ebata, Akiko ^a   Ishida, Takanori ^a   Watanabe, Mika ^b   Sasano, Hironobu ^a,b   Suzuki, Takashi ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; SMALL INTERFERING RNA;

ADULT; ADVERSE OUTCOME; AGED; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER PATIENT; CANCER RISK; CARCINOMA CELL; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MICROARRAY ANALYSIS; MULTIVARIATE ANALYSIS; NUCLEOBINDIN 2 GENE; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROGNOSIS; RECEPTOR UPREGULATION; RECURRENCE RISK; UNIVARIATE ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; BREAST NEOPLASMS; CALCIUM-BINDING PROTEINS; CARCINOMA, DUCTAL, BREAST; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; DNA-BINDING PROTEINS; ESTROGENS; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION PROFILING; HUMANS; IMMUNOENZYME TECHNIQUES; LASER CAPTURE MICRODISSECTION; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ESTROGEN; RNA, MESSENGER; RNA, SMALL INTERFERING; SURVIVAL RATE; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84855487960     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2011.02119.x     Document Type: Article

References (31)

1. Jordan VC. Fourteenth Gaddum Memorial Lecture. A current view of tamoxifen for the treatment and prevention of breast cancer. Br J Pharmacol 1993; 110: 507-17.
2. Ali S, Coombes RC. Endocrine-responsive breast cancer and strategies for combating resistance. Nat Rev Cancer 2002; 2: 101-12.
3. Suzuki T, Inoue A, Miki Y et al. Early growth responsive gene 3 in human breast carcinoma: a regulator of estrogen-meditated invasion and a potent prognostic factor. Endocr Relat Cancer 2007; 14: 279-92.
4. Frasor J, Danes JM, Komm B, Chang KC, Lyttle CR, Katzenellenbogen BS. Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 2003; 144: 4562-74.
5. Hayashi SI, Eguchi H, Tanimoto K et al. The expression and function of estrogen receptor alpha and beta in human breast cancer and its clinical application. Endocr Relat Cancer 2003; 10: 193-202.
6. Miura K, Titani K, Kurosawa Y, Kanai Y. Molecular cloning of nucleobindin, a novel DNA-binding protein that contains both a signal peptide and a leucine zipper structure. Biochem Biophys Res Commun 1992; 187: 375-80.
7. Barnikol-Watanabe S, Gross NA, Götz H et al. Human protein NEFA, a novel DNA binding/EF-hand/leucine zipper protein. Molecular cloning and sequence analysis of the cDNA, isolation and characterization of the protein. Biol Chem Hoppe Seyler 1994; 375: 497-512.
8. Taniguchi N, Taniura H, Niinobe M et al. The postmitotic growth suppressor necdin interacts with a calcium-binding protein (NEFA) in neuronal cytoplasm. J Biol Chem 2000; 275: 31674-81.
9. Oh IS, Shimizu H, Satoh T et al. Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature 2006; 443: 709-12.
10. Islam A, Adamik B, Hawari FI et al. Extracellular TNFR1 release requires the calcium-dependent formation of a nucleobindin 2-ARTS-1 complex. J Biol Chem 2006; 281: 6860-73.
11. Elston CW, Ellis IO. Pathological prognostic factors in breast-cancer. 1. The value of histological grade in breast-cancer -experience from a large study with long-term follow-up. Histopathology 1991; 19: 403-10.
12. Miki Y, Suzuki T, Kitada K et al. Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma. Cancer Res 2006; 66: 535-42.
13. Nagasaki S, Suzuki T, Miki Y et al. 17Beta-hydroxysteroid dehydrogenase type 12 in human breast carcinoma: a prognostic factor via potential regulation of fatty acid synthesis. Cancer Res 2009; 69: 1392-9.
14. Bourdeau V, Deschênes J, Me′tivier R et al. Genomewide identification of high-affinity estrogen response elements in human and mouse. Mol Endocrinol 2004; 18: 1411-27.
15. Kalnina Z, Silina K, Bruvere R et al. Molecular characterisation and expression analysis of SEREX-defined antigen NUCB2 in gastric epithelium, gastritis and gastric cancer. Eur J Histochem 2009; 53: 7-18.
16. Takagi K, Miki Y, Nagasaki S et al. Increased intratumoral androgens in human breast carcinoma following aromatase inhibitor exemestane treatment. Endocr Relat Cancer 2010; 17: 415-30.
17. Oka K, Suzuki T, Onodera Y et al. Nudix-type motif 2 in human breast carcinoma: a potent prognostic factor associated with cell proliferation. Int J Cancer 2011; 128: 1770-82.
18. Ramanjaneya M, Chen J, Brown JE et al. Identification of nesfatin-1 in human and murine adipose tissue: a novel depot-specific adipokine with increased levels in obesity. Endocrinology 2010; 151: 3169-80.
19. Oh DS, Troester MA, Usary J et al. Estrogen-regulated genes predict survival in hormone receptor-positive breast cancers. J Clin Oncol 2006; 24: 1656-64.
20. Huang E, Cheng SH, Dressman H et al. Gene expression predictors of breast cancer outcomes. Lancet 2003; 361: 1590-6.
21. Naoi Y, Kishi K, Tanei T et al. Development of 95-gene classifier as a powerful predictor of recurrences in node-negative and ER-positive breast cancer patients. Breast Cancer Res Treat 2011; 128: 633-41.
22. van't Veer LJ, Dai H, van de Vijver MJ et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002; 415: 530-6.
23. Paik S. Development and clinical utility of a 21-gene recurrence score prognostic assay in patients with early breast cancer treated with tamoxifen. Oncologist 2007; 12: 631-5.
24. Sotiriou C, Wirapati P, Loi S et al. Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. J Natl Cancer Inst 2006; 98: 262-72.
25. Hao X, Sun B, Hu L et al. Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis. Cancer 2004; 100: 1110-22.
26. Li X, Cao X, Li X, Zhang W, Feng Y. Expression level of insulin-like growth factor binding protein 5 mRNA is a prognostic factor for breast cancer. Cancer Sci 2007; 98: 1592-6.
27. Booth BW, Smith GH. Roles of transforming growth factor-alpha in mammary development and disease. Growth Factors 2007; 25: 227-35.
28. Klebig C, Korinth D, Meraldi P. Bub1 regulates chromosome segregation in a kinetochore-independent manner. J Cell Biol 2009; 185: 841-58.
29. García-Galiano D, Navarro VM, Gaytan F, Tena-Sempere M. Expanding roles of NUCB2/nesfatin-1 in neuroendocrine regulation. J Mol Endocrinol 2010; 45: 281-90.
30. Osborne CK, Coronado-Heinsohn EB, Hilsenbeck SG et al. Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer. J Natl Cancer Inst 1995; 87: 746-50.
31. Dauvois S, White R, Parker MG. The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling. J Cell Sci 1993; 106: 1377-88.