Antitumor activity of Aloe vera against Ehrlich ascitis carcinoma (EAC) in Swiss albino mice

International Journal of Pharma and Bio Sciences

Volumn 2, Issue 2, 2011, Pages 400-409

  Naveena, ^a   Bharath, B K ^b   Selvasubramanian, ^a  

^a MADRAS VETERINARY COLLEGE   (India)

^b CVSc SVV University   (India)

Author keywords

Aloe vera; Antineoplastic agents; Antioxidants; Ehrlich ascites carcinoma

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; ALOE VERA EXTRACT; ASPARTATE AMINOTRANSFERASE; CATALASE; FLUOROURACIL; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; LIPID; SUPEROXIDE DISMUTASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ALOE VERA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD ANALYSIS; BODY WEIGHT; CONTROLLED STUDY; EHRLICH ASCITES TUMOR; GLUCOSE BLOOD LEVEL; INOCULATION; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; LIVER METASTASIS; MOUSE; NONHUMAN; PLANT LEAF; SPLEEN CANCER; SPLEEN METASTASIS; TREATMENT DURATION; TREATMENT OUTCOME; TUMOR GROWTH; WEIGHT REDUCTION;

ALOE VERA; MUS;

EID: 84855474874     PISSN: None     EISSN: 09756299     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Abdullaev, F.I., Plant-derived agents against cancer. In: Pharmacology and Therapeutics in the New Millennium, New Delhi. 345-354, (2001).
2. Abdullaev, F.I., R.R.Luna, B.V.Roitenburd, A.J.Espinosa, Pattern of childhood cancer mortality in Mexico. Arch. Med. Res., 31: 526-31, (2000).
3. Reynolds, T. and A.C.Dweck, Aloe vera leaf gel: a review update. J. Ethnopharmacol., 68: 3-37. (1999).
4. Heggers J, et al. Beneficial effects of aloe in wound healing. Phytother Res. 7: S48-S52.
5. Vazquez B, et al. 1996. Anti-inflammatory activity of extracts from aloe vera gel. JEthnopharmacol. 55:69-75,(1993).
6. Saoo K, et al.. Antiviral activity of aloe extracts against cytomegalovirus. Phytother Res. 10:348-350,(1996).
7. Fahim MS, Wang M. Zinc acetate and lyophilized Aloe barbadensis as vaginal contraceptive. Contraception. 53:231-236,(1996).
8. Danhof I. Potential benefits from orallyinjested internal aloe vera gel. International Aloe Science Council Tenth Annual Aloe Scientific Semina; Irving, Texas,(1991).
9. Zhang L, Tizard IR. Activation of a mouse macrophage cell line by acemannan: the major carbohydrate fraction from Aloe vera gel; Immunopharmacology. 35:119-28,(1996).
10. DeFeudis FV, Papadopoulos V, Drieu K.. Ginkgo biloba extracts and cancer: a research area in its infancy. Fundam Clin Pharmacol., 17: 405-17, (2003).
11. Takeoka GR, Dao LT. Antioxidant constituent of almond [Prunus dulcis (Mill.) D.A. Webb.] hulls. J Agric Food Chem., 51: 496-501,2003).
12. Dacie, J.V. and S.M.Lewis, Practical Hematology. 2nd ed. London: J and A Churchill; 38-48. (1958).
13. Yagi, K., Simple fluorimetric assay for lipid peroxides in blood plasma. Biochem. Med., 15: 212-216,(1976).
14. Moron, M.S., J.W.Depierre and B.Mannervik, Levels of glutathione, glutathione reductase and glutathione- Stransferase activities in rat lung and liver. Biochim. Biophys. Acta., 582: 67-78(1979).
15. Marklund, S.L and G.Marklund, Involvement of superoxide anion radical in the autooxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem., 47: 496-474,(1974).
16. Caliborne, A.L.,. Assay of catalase. In. Handbook of Oxygen Radical Research. Ed. Greenward, R.A., CRC Press, Baco-Raton,(1985).
17. Rotruck, J.D., A.L.Pope, H.E.Ganther, A.B.Swanson, D.G.Hafeman and Hekstra,. Selenium biochemical role as a component of glutathione peroxidase and assay. Science, 179: 588-590,(1973).
18. Culling C F A, Hand book of Histopathological and Histochemical Techniques (including museum techniques) 3rd ed. Pp.361,(1974).
19. Price, V.E and R.E.Greenfield,. Anemia in cancer, In: Greenstein JP, Haddow A, editors. Advances in cancer research; v 5. New York: Academic Press; 199-200,(1958).
20. Maseki M, I.Nishiagaki, M.Hagishara, Y.Tomoda and K.Yagi,. Lipid peroxidation levels and lipid content of serum lipoprotein fractions of pregnant subjects with or with out preeclampsia. J Clin Chim Acta., 41: 424-426,(1981).
21. Fenninger, L.D. and G.B.Mider,. In: Advances in cancer research. Grenstein JP, Haddow A, editors. v 2. New York: Academic Press; p 244,(1954).
22. Sun Y, Oberley LW, Elwell JH, Sierra Rivera E. Antioxidant enzyme activities in normal and transformed mice liver cells. Int. J. Cancer. 44: 1028-33,(1989).
23. Marklund SL, Westman NG, Lundgren E, Roos G. Copper and zinc containing superoxide dismutase, manganesecontaining superoxide dismutase, catalase, and glutathione peroxidase in normal and neoplastic human cell lines and normal human tissues. Cancer Res., 42: 1955-1961,(1982).
24. Jiau-Jian L, Larry WO. Over expression of manganese-containing superoxide dismutase confers resistance to the cytotoxicity of tumor necrosis factor α and/or hyperthermia. Cancer Res., 57: 1991-1998,(1977)
25. Ruby AJ, Kuttan G, Babu KD, Rajasekharan KN, Kuttan R. Antitumor and antioxidant activity of natural curcuminoids. Cancer Lett., 94: 783-789,(1995).