Physical exercise improves cardiac autonomic modulation in hypertensive patients independently of angiotensin-converting enzyme inhibitor treatment

Hypertension Research

Volumn 35, Issue 1, 2012, Pages 82-87

  Cozza, Izabela C ^a   Di Sacco, Thaisa H R ^a   Mazon, José H ^a   Salgado, Maria Cristina O ^a   Dutra, Sabrina G V ^a   Cesarino, Evandro J ^a   Souza, Hugo C D ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

aerobic physical training; angiotensin; heart rate variability

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ADULT; AEROBIC EXERCISE; ANTHROPOMETRIC PARAMETERS; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; ELECTROCARDIOGRAM; FEMALE; HEART RATE VARIABILITY; HUMAN; HYPERTENSION; LABORATORY TEST; MALE; SEDENTARY LIFESTYLE; SUPINE POSITION; TIME SERIES ANALYSIS;

ADULT; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; AUTONOMIC NERVOUS SYSTEM; BLOOD PRESSURE; ENALAPRIL; EXERCISE; FEMALE; HEART RATE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; SEDENTARY LIFESTYLE; TILT-TABLE TEST;

EID: 84855450382     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2011.162     Document Type: Article

References (46)

1. Kannel WB. Framingham study insights into hypertensive risk of cardiovascular disease. Hypertens Res 1995; 18: 181-196.
2. Kearneya PM, Wheltona M, Reynoldsa K, Wheltona PK, He J. Worldwide prevalence of hypertension: a systematic review. J Hypertens 2004; 22: 11-19. (Pubitemid 38293521)
3. Whelton PK. Epidemiology of hypertension. Lancet 1994; 344: 101-106. (Pubitemid 24214139)
4. He J, Bazzano LA. Effects of lifestyle modification on treatment and prevention of hypertension. Curr Opin Neph Hyp 2000; 9: 267-271. (Pubitemid 30266207)
5. Cupples LA, D'agostino RB. Section 34: some risk factors related to the annual incidence of cardiovascular disease and death in pooled repeated biennial measurements. In: Kannel WB, Wolf PA, Garrison RJ, (eds) Framingham Heart Study: 30 Year Follow FollUp. Bethesda 1987, pp 1-22.
6. Perret-Guillaume C, Joly L, Jankowski P, Benetos A. Benefits of the RAS blockade: clinical evidence before the ONTARGET study. J Hypertens 2009; 27 (suppl 2): S3-S7.
7. Duprez DA. Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review. J Hypertens 2006; 24: 983-991. (Pubitemid 43772300)
8. Mizuno Y, Jacob RF, Mason RP. Effects of calcium channel and renin-angiotensin system blockade on intravascular and neuro-hormonal mechanisms of hypertensive vascular disease. Am J Hypertens 2008; 21: 1076-1085.
9. Zhang GQ, Zhu Z, Zhang W. Inhibitory effect of antihypertensive drugs on calcineurin in cardiomyocytes. Am J Hypertens 2009; 22: 132-136.
10. Ball SG. The sympathetic nervous system and converting enzyme inhibition. J Cardiovasc Pharmacol 1989; 13: S17-S21. (Pubitemid 19172480)
11. Karas M, Lacourcière Y, Leblanc AR, Nadeau R, Dubé B, Florescu M, Lamarre-Cliche M, Poirier L, Larochelle P, De Champlain J. Effect of the renin-angiotensin system or calcium channel blockade on the circadian variation of heart rate variability, blood pressure and circulating catecholamines in hypertensive patients. J Hypertens 2005; 23: 1137-1139.
12. Dias da Silva VJ, Montano N, Salgado HC, Fazan Júnior R. Effects of long-term angiotensin converting enzyme inhibition on cardiovascular variability in aging rats. Auton Neurosci 2006; 124: 49-55.
13. Fagard RH, Cornelissen VA. Effect of exercise on blood pressure control in hypertensive patients. Eur J Card Prev Rehab 2007; 14: 12-17.
14. Whelton SP, Chin A, Zin Z, He J. Effects of aerobic exercise on blood pressure: a metaanalysis of randomized controlled trials. Ann Intern Med 2002; 136: 493-503. (Pubitemid 34252283)
15. Izdebska E, Cybulska I, Izdebski J, Makowiecka-Ciesla M, Trebski A. Effects of Moderate Physical Training on Blood Pressure Variability and Hemodynamic Pattern in Mildly Hypertensive Subjects. J Physiol Pharmcol 2004; 55: 713-724. (Pubitemid 40053040)
16. Cornelissen VA, Fagard RH. Effects of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors. Hypertension 2005; 46: 667-675. (Pubitemid 43186737)
17. Kokkinos P, Nrayan P, Papademetriou V. Exercise as hypertension therapy. Cardiol Clin 2001; 19: 507-516. (Pubitemid 32852084)
18. Laterza MC, de Matos L, Trombetta CI, Braga AMW, Roveda F, Alves MJ, Krieger EM, Negrão CE, Rondon MU. Exercise Training Restores Baroreflex Sensitivity in Never-Treated Hypertensive Patients. Hypertension 2007; 49: 1298-1306. (Pubitemid 46809372)
19. Carter JB, Banister EW, Blaber AP. Effect of endurance exercise on autonomic control of heart rate. Sports Med 2003; 33: 33-46. (Pubitemid 36078542)
20. Souza HCD, de Araujo JE, Martins-Pinge MC, Cozza IC, Martins-Dias DP. Nitric oxide synthesis blockade reduced the baroreflex sensitivity in trained rats. Auton Neurosci Basic Clin 2009; 150: 38-44.
21. Collier SR, Kanaley JA, Carhart Jr R, Frechette V, Tobin MM, Bennett N, Luckenbaugh AN, Fernhall B. Cardiac autonomic function and baroreflex changes following 4 weeks of resistance versus aerobic training in volunteers with pre-hypertension. Acta Physiol (Oxf) 2009; 195: 339-348.
22. Sloan RP, Shapiro PA, DeMeersman RE, Bagiella E, Brondolo EN, McKinley PS, Slavov I, Fang Y, Myers MM. The effect of aerobic training and cardiac autonomic regulation in young adults. Am J Public Health 2009; 99: 921-928.
23. Piotrowicz E, Baranowski R, Piotrowska M, Zieliñ ski T, Piotrowicz R. Variable effects of physical training of heart rate variability, heart rate recovery, and heart rate turbulence in chronic heart failure. Pacing Clin Electrophysiol 2009; 32(suppl 1): S113-S115.
24. Malliani A, Pagani M, Lombardi F, Cerutti S. Cardiovascular neural regulation explored in the frequency domain. Circulation 1991; 84: 482-492.
25. Rubini R, Porta A, Baselli G, Cerutti S, Paro M. Power spectrum analysis of cardiovascular variability monitored by telemetry in conscious unrestrained rats. J Auton Nerv Syst 1993; 45: 181-190. (Pubitemid 24010158)
26. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Circulation 1996; 93: 1043-1065.
27. Schlaich MP, Lambert E, Kaye DM, Krozowski Z, Campbell DJ, Lambert G, Hastings J, Aggarwal A, Esler MD. Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and Angiotensin neuromodulation. Hypertension 2004; 43: 169-175. (Pubitemid 38174169)
28. Neumann J, Ligtenberg G, Klein IH, Boer P, Oey PL, Koomans HA, Blankestijn PJ. Sympathetic hyperactivity in hypertensive chronic kidney disease patients is reduced during standard treatment. Hypertension 2007; 49: 506-510.
29. Grassi G. Assessment of sympathetic cardiovascular drive in human hypertension: achievements and perspectives. Hypertension 2009; 54: 690-697.
30. Townend JN, al-Ani M, West JN, Littler WA, Coote JH. Modulation of cardiac autonomic control in humans by angiotensin II. Hypertension 1995; 25: 1270-1275.
31. Pagani M, Lucini D. Autonomic dysregulation in essential hypertension: insight from heart rate and arterial pressure variability. Auton Neurosci 2001; 90: 76-82. (Pubitemid 32547227)
32. Lucini D, Mela GS, Malliani A, Pagani M. Impairment in cardiac autonomic regulation preceding arterial hypertension in humans: insights from spectral analysis of beat-bybeat cardiovascular variability. Circulation 2002; 106: e9051.
33. Frohlich ED, Tarazi RC, Ulrych M, Dustan HP, Page IH. Tilt test for investigating a neural component in hypertension: Its correlation with clinical characteristics. Circulation 1967; 36: 387-393.
34. Goldstein RE, Beiser GD, Stampfer M, Epstein SE. Impairment of autonomically mediated heart rate control in patients with cardiac dysfunction. Circ Res 1975; 36: 571-578.
35. Pavithran P, Mithun R, Jomal M, Nandeesha H. Heart rate variability in middleaged men with new-onset hypertension. Ann Noninvasive Electrocardiol 2008; 13: 242-248. (Pubitemid 351994118)
36. Petretta M, Bonaduce D, Marciano F, Bianchi V, Valva G, Apicella C, De Luca N, Gisonni P. Effect of 1 year of lisinopril treatment on cardiac autonomic control in hypertensive patients with left ventricular hypertrophy. Hypertension 1996; 27(3 Pt 1): 330-338. (Pubitemid 26083051)
37. Chern CM, Hsu HY, Hu HH, Chen YY, Hsu LC, Chao AC. Effects of atenolol and losartan on baroreflex sensitivity and heart rate variability in uncomplicated essential hypertension. Cardiovasc Pharmacol 2006; 47: 169-174.
38. Matsukawa S, Reid IA. Role of the area postrema in the modulation of the baroreflex control of heart rate by angiotensin II. Circ Res 1990; 67: 1462-1473.
39. DiBona GF. Peripheral and central interactions between the renin-angiotensin system and the renal sympathetic nerves in control of renal function. Ann N Y Acad Sc 2001; 940: 395-406.
40. Tan PS, Killinger S, Horiuchi J, Dampney RA. Baroreceptor reflex modulation by circulating angiotensin II is mediated by AT1 receptors in the nucleus tractus solitarius. Am J Physiol Regul Integr Comp Physiol 2007; 293: R2267-R2278. (Pubitemid 350224020)
41. Manfredini F, Malagoni AM, Mandini S, Boari B, Felisatti M, Zamboni P, Manfredini R. Sport therapy for hypertension: why, how, and how much? Angiology 2009; 60: 207-216.
42. Zucker IH, Schultz HD, Li YF, Wang Y, Wang W, Patel KP. The origin of sympathetic outflow in heart failure: the roles of angiotensin II and nitric oxide. Prog Biophys Mol Biol 2004; 84: 217-232. (Pubitemid 38215213)
43. Zheng H, Li YF, Cornish KG, Zucker IH, Patel KP. Exercise training improves endogenous nitric oxide mechanisms within the paraventricular nucleus in rats with heart failure. Am J Physiol Heart Circ Physiol 2005; 288: H2332-H2341. (Pubitemid 40604122)
44. Mueller PJ, Foley CM, Hasser EM. Hindlimb unloading alters nitric oxide and autonomic control of resting arterial pressure in conscious rats. Am J Physiol Regul Integr Comp Physiol 2005; 289: R140-R147. (Pubitemid 40874969)
45. Felix JV, Michelini LC. Training-induced pressure fall in spontaneously hypertensive rats is associated with reduced angiotensinogen mRNA expression within the nucleus tractus solitarii. Hypertension 2007; 50: 780-785. (Pubitemid 47442745)
46. De Abreu SB, Lenhard A, Mehanna A, de Souza HC, Correa FM, Hasser EM, Martins-Pinge MC. Role of paraventricular nucleus in exercise training-induced autonomic modulation in conscious rats. Auton Neurosci 2009; 148: 28-35.