Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1

Cell Metabolism

Volumn 15, Issue 1, 2012, Pages 75-87

  Zhang, Tengfei ^a,b   Wang, Shiwen ^a,b   Lin, Yan ^b   Xu, Wei ^a,b   Ye, Dan ^b   Xiong, Yue ^a,b,d   Zhao, Shimin ^a,b   Guan, Kun Liang ^a,b,c,e,f  

^a FUDAN UNIVERSITY   (China)

^b Institutes of Biomedical Sciences   (China)

^c FUDAN UNIVERSITY   (China)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e Department of Pharmacology ^*  (United States)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON; GLUCOSE; GLYCOGEN PHOSPHORYLASE; INSULIN; LYSINE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 1ALPHA; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; GLYCOGEN METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ACETYLATION; ANIMALS; GLUCOSE; GLYCOGEN; GLYCOGEN PHOSPHORYLASE; INSULIN; LYSINE; MALE; MICE; MICE, INBRED BALB C; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PHOSPHATASE 1;

EID: 84855449701     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2011.12.005     Document Type: Article

References (36)

1. S. Alemany, and P. Cohen Phosphorylase a is an allosteric inhibitor of the glycogen and microsomal forms of rat hepatic protein phosphatase-1 FEBS Lett. 198 1986 194 202 (Pubitemid 16078848)
2. V.G. Allfrey, R. Faulkner, and A.E. Mirsky Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis Proc. Natl. Acad. Sci. USA 51 1964 786 794
3. A.L. Andreu, G. Nogales-Gadea, D. Cassandrini, J. Arenas, and C. Bruno McArdle disease: molecular genetic update Acta Myol. 26 2007 53 57 (Pubitemid 47400726)
4. C.G. Armstrong, M.J. Doherty, and P.T. Cohen Identification of the separate domains in the hepatic glycogen-targeting subunit of protein phosphatase 1 that interact with phosphorylase a, glycogen and protein phosphatase 1 Biochem. J. 336 1998 699 704 (Pubitemid 29008030)
5. D. Barford, and L.N. Johnson The allosteric transition of glycogen phosphorylase Nature 340 1989 609 616 (Pubitemid 19202571)
6. D. Barford, S.H. Hu, and L.N. Johnson Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP J. Mol. Biol. 218 1991 233 260 (Pubitemid 121003342)
7. M.J. Brady, J.A. Printen, C.C. Mastick, and A.R. Saltiel Role of protein targeting to glycogen (PTG) in the regulation of protein phosphatase-1 activity J. Biol. Chem. 272 1997 20198 20204 (Pubitemid 27340130)
8. M.F. Browner, and R.J. Fletterick Phosphorylase: a biological transducer Trends Biochem. Sci. 17 1992 66 71
9. J.L. Buchbinder, C.B. Luong, M.F. Browner, and R.J. Fletterick Partial activation of muscle phosphorylase by replacement of serine 14 with acidic residues at the site of regulatory phosphorylation Biochemistry 36 1997 8039 8044 (Pubitemid 27284180)
10. C. Choudhary, C. Kumar, F. Gnad, M.L. Nielsen, M. Rehman, T.C. Walther, J.V. Olsen, and M. Mann Lysine acetylation targets protein complexes and co-regulates major cellular functions Science 325 2009 834 840
11. P. Cohen The subunit structure of rabbit-skeletal-muscle phosphorylase kinase, and the molecular basis of its activation reactions Eur. J. Biochem. 34 1973 1 14
12. C.F. Cori, and G.T. Cori Mechansim of formation of hexosemonophosphate in muscle and isolation of a new phosphate ester Proc. Soc. Exp. Biol. Med. 34 1936 702 705
13. T. Finkel, C.X. Deng, and R. Mostoslavsky Recent progress in the biology and physiology of sirtuins Nature 460 2009 587 591
14. E.H. Fischer, and E.G. Krebs Conversion of phosphorylase b to phosphorylase a in muscle extracts J. Biol. Chem. 216 1955 121 132
15. K.L. Guan, and Y. Xiong Regulation of intermediary metabolism by protein acetylation Trends Biochem. Sci. 36 2011 108 116
16. W.C. Hallows, S. Lee, and J.M. Denu Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases Proc. Natl. Acad. Sci. USA 103 2006 10230 10235 (Pubitemid 44051149)
17. T. Hunter The age of crosstalk: phosphorylation, ubiquitination, and beyond Mol. Cell 28 2007 730 738 (Pubitemid 350217067)
18. W. Jiang, S. Wang, M. Xiao, Y. Lin, L. Zhou, Q. Lei, Y. Xiong, K.-L. Guan, and S. Zhao Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase Mol. Cell 43 2011 33 44
19. L.N. Johnson Glycogen phosphorylase: control by phosphorylation and allosteric effectors FASEB J. 6 1992 2274 2282
20. T.H. Jones, and B.E. Wright Partial purification and characterization of glycogen phosphorylase from Dictyostelium discoideum J. Bacteriol. 104 1970 754 761
21. I.R. Kelsall, S. Munro, I. Hallyburton, J.L. Treadway, and P.T. Cohen The hepatic PP1 glycogen-targeting subunit interaction with phosphorylase a can be blocked by C-terminal tyrosine deletion or an indole drug FEBS Lett. 581 2007 4749 4753 (Pubitemid 47418802)
22. G.W. Kim, and X.J. Yang Comprehensive lysine acetylomes emerging from bacteria to humans Trends Biochem. Sci. 36 2011 211 220
23. S.C. Kim, R. Sprung, Y. Chen, Y. Xu, H. Ball, J. Pei, T. Cheng, Y. Kho, H. Xiao, and L. Xiao Substrate and functional diversity of lysine acetylation revealed by a proteomics survey Mol. Cell 23 2006 607 618 (Pubitemid 44205490)
24. S. Lok, J.L. Kuijper, L.J. Jelinek, J.M. Kramer, T.E. Whitmore, C.A. Sprecher, S. Mathewes, F.J. Grant, S.H. Biggs, and G.B. Rosenberg The human glucagon receptor encoding gene: structure, cDNA sequence and chromosomal localization Gene 140 1994 203 209 (Pubitemid 24115231)
25. J. Massague, and J.J. Guinovart Insulin control of rat hepatocyte glycogen synthase and phosphorylase in the absence of glucose FEBS Lett. 82 1977 317 320 (Pubitemid 8206193)
26. C. Nolan, W.B. Novoa, E.G. Krebs, and E.H. Fischer Further studies on the site phosphorylated in the Phosphorylase B to a reaction Biochemistry 3 1964 542 551
27. A. Pautsch, N. Stadler, O. Wissdorf, E. Langkopf, W. Moreth, and R. Streicher Molecular recognition of the protein phosphatase 1 glycogen targeting subunit by glycogen phosphorylase J. Biol. Chem. 283 2008 8913 8918
28. D.M. Phillips The presence of acetyl groups of histones Biochem. J. 87 1963 258 263
29. S. Shenolikar, P.T.W. Cohen, P. Cohen, A.C. Nairn, and S.V. Perry The role of calmodulin in the structure and regulation of phosphorylase kinase from rabbit skeletal muscle Eur. J. Biochem. 100 1979 329 337 (Pubitemid 10165881)
30. B.L. Stegelmeier, R.J. Molyneux, A.D. Elbein, and L.F. James The lesions of locoweed (Astragalus mollissimus), swainsonine, and castanospermine in rats Vet. Pathol. 32 1995 289 298
31. E.W. Sutherland Jr., and W.D. Wosilait Inactivation and activation of liver phosphorylase Nature 175 1955 169 170
32. N.L. Tang, J. Hui, E. Young, V. Worthington, K.F. To, K.L. Cheung, C.K. Li, and T.F. Fok A novel mutation (G233D) in the glycogen phosphorylase gene in a patient with hepatic glycogen storage disease and residual enzyme activity Mol. Genet. Metab. 79 2003 142 145 (Pubitemid 36693934)
33. Q. Wang, Y. Zhang, C. Yang, H. Xiong, Y. Lin, J. Yao, H. Li, L. Xie, W. Zhao, and Y. Yao Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux Science 327 2010 1004 1007
34. W.S. Xu, R.B. Parmigiani, and P.A. Marks Histone deacetylase inhibitors: molecular mechanisms of action Oncogene 26 2007 5541 5552 (Pubitemid 47255934)
35. X.J. Yang, and E. Seto Lysine acetylation: codified crosstalk with other posttranslational modifications Mol. Cell 31 2008 449 461
36. S. Zhao, W. Xu, W. Jiang, W. Yu, Y. Lin, T. Zhang, J. Yao, L. Zhou, Y. Zeng, and H. Li Regulation of cellular metabolism by protein lysine acetylation Science 327 2010 1000 1004