Chemical composition, antioxidant and cytotoxicity activities of the essential oils of Myristica fragrans and Morinda citrifolia

Journal of the Science of Food and Agriculture

Volumn 92, Issue 3, 2012, Pages 593-597

  Piaru, Suthagar Pillai ^a   Mahmud, Roziahanim ^a   Abdul Majid, Amin Malik Shah ^a   Ismail, Sabariah ^b   Man, Che Nin ^b  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

^b SCHOOL OF PHYSICS   (Malaysia)

Author keywords

Antioxidant activity; Cytotoxic activity; Essential oil; Morinda citrifolia; Myristica fragrans

Indexed keywords

MORINDA CITRIFOLIA; MYRISTICA FRAGRANS;

ANTINEOPLASTIC AGENT; ANTIOXIDANT; ESSENTIAL OIL;

BREAST NEOPLASMS; CARCINOMA; CELL PROLIFERATION; CHEMISTRY; COLORECTAL NEOPLASMS; DRUG DEVELOPMENT; DRUG EFFECTS; ETHNOPHARMACOLOGY; FEMALE; FRUIT; HCT116 CELL LINE; HUMAN; ISOLATION AND PURIFICATION; MALAYSIA; MALE; MASS FRAGMENTOGRAPHY; MCF 7 CELL LINE; MORINDA; NUTMEG; OSMOLARITY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; BREAST NEOPLASMS; CARCINOMA; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DRUG DISCOVERY; ETHNOPHARMACOLOGY; FEMALE; FRUIT; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HCT116 CELLS; HUMANS; MALAYSIA; MALE; MCF-7 CELLS; MORINDA; MYRISTICA FRAGRANS; OILS, VOLATILE; OSMOLAR CONCENTRATION;

EID: 84855414078     PISSN: 00225142     EISSN: 10970010     Source Type: Journal    
DOI: 10.1002/jsfa.4613     Document Type: Article

References (19)

1. Heath HB. (1981). Source Book of Flavours. AVI, Westport, VA.
2. Tepe B, Donmez E, Unlu M, Candan F, Daferera D, Vardar-Unlu G, et al, Antimicrobial and antioxidative activities of the essential oils and methanol extracts of Salvia cryptantha (Montbret et Aucher ex Benth) and Salvia multicaulis (Vahl). Food Chem 84: 519-525 (2004).
3. Baratta MT, Dorman HJD, Deans SG, Biondi DM and Ruberto G, Chemical composition, antimicrobial and antioxidative activity of laurel, sage, rosemary, oregano and coriander essential oils. J Essential Oil Res 10: 618-627 (1998).
4. Chatterjee S, Niaz Z, Gautam S, Adhikari S, Variyar PS and Sharma A, Antioxidant activity of some phenolic constituents from green pepper (Piper nigrum L.) and fresh nutmeg mace (Myristica fragrans). Food Chem 101: 515-523 (2007).
5. Spricigo CB, Pinto LT, Bolzan A and Novais AF, Extraction of essential oil and lipids from nutmeg by liquid carbon dioxide. J Supercrit Fluids 15: 253-259 (1999).
6. Morita T, Jinno K, Kawagishi H, Arimoto Y, Suganuma H, Inakuma T, et al, Hepatoprotective effect of myristicin from nutmeg (Myristica fragrans) on lipopolysaccharide/d-galactosamine-induced liver injury. J Agric Food Chem 51: 1560-1565 (2003).
7. Morton J, The ocean-going noni, or Indian mulberry (Morinda citrifolia, Rubiaceae) and some of its 'colorful' relatives. Econ Bot 46: 241-256 (1992).
8. Levand O and Larson HO, Some chemical constituents of Morinda citrifolia. Planta Med 36: 186-187 (1979).
9. Shimada K, Fujikawa K, Yahara K and Nakamura T, Antioxidative properties of xanthan on the autoxidation of soybean oil in cyclodextrin emulsion. J Agric Food Chem 40: 945-948 (1992).
10. Singh HP, Kaur S, Mittal S, Batish DR and Kohli RK, Phytotoxicity of major constituents of volatile oil from leaves of Artemisia scoparia Waldst & Kit. Z Naturforsch C 63: 663-666 (2008).
11. Mosmann T, Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Meth 65: 55-63 (1983).
12. Dorman HJD, Figueiredo AC, Barroso JG and Deans SG, In vitro evaluation of antioxidant activity of essential oils and their components. Flavour Fragrance J 15: 12-16 (2000).
13. Gulcin I, Oktay M, Kufrevioglu OI and Aslan A, Determination of antioxidant activity of lichen Cetraria islandica (L). Ach. J Ethnopharmacol 79: 325-329 (2002).
14. Lee EY, Chung CH, Kim JH, Jung HJ and Hong SY, Antioxidants ameliorate the expression of vascular endothelial growth factor mediated by protein kinase C in diabetic podocytes. Nephrol Dial Transplant 21: 1496-1503 (2006).
15. Lee BK, Kim JH, Jung JW, Choi JW, Han ES, Lee SH, et al, Myristicin-induced neurotoxicity in human neuroblastoma SK-N-SH cells. Toxicol Lett 157: 49-56 (2005).
16. Parija T and Das B, Involvement of YY1 and its correlation with c-myc in NDEA induced hepatocarcinogenesis, its prevention by d-limonene. Mol Biol Rep 30: 41-46 (2003).
17. Calcabrini A, Stringaro A, Toccacieli L, Meschini S, Marra M, Colone M, et al, Terpinen-4-ol, the main component of Melaleuca Alternifolia (tea tree) oil inhibits the in vitro growth of human melanoma cells. J Invest Dermatol 122: 349-360 (2004).
18. Hussain A, Sasidharan S, Ahmed T, Ahmed M and Sharma C, Clove (Syzygium aromaticum) extract potentiates gemcitabine cytotoxic effect on human cervical cancer cell line. Int J Cancer Res 5: 95-104 (2009).
19. Hirazumi A and Furusawa E, An immunomodulatory polysaccharide-rich substance from the fruit juice of Morinda citrifolia (noni) with antitumour activity. Phytother Res 13: 380-387 (1999).