메뉴 건너뛰기




Volumn 30, Issue 1, 2012, Pages 42-47

Concise review: Induced pluripotent stem cell-derived mesenchymal stem cells: Progress toward safe clinical products

Author keywords

Cellular therapy; Clinical trials; Induced pluripotent stem cells; Mesenchymal stem cells; Regenerative medicine

Indexed keywords

CELL THERAPY AGENT; GENE THERAPY AGENT; HERMES ANTIGEN; IMMUNOSUPPRESSIVE AGENT; KRUPPEL LIKE FACTOR 4; LENTIVIRUS VECTOR; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; RETROVIRUS VECTOR; TRANSCRIPTION FACTOR SOX2; VASCULOTROPIN;

EID: 84855407207     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.727     Document Type: Review
Times cited : (222)

References (62)
  • 1
  • 2
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145-1147. (Pubitemid 28516247)
    • (1998) Science , vol.282 , Issue.5391 , pp. 1145-1147
    • Thomson, J.A.1
  • 3
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676. (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 4
    • 12644281737 scopus 로고
    • Homografts of bone marrow in dogs after lethal total-body radiation
    • Thomas ED, Ashley CA, Lochte HL, Jr. et al. Homografts of bone marrow in dogs after lethal total-body radiation. Blood 1959;14:720-736.
    • (1959) Blood , vol.14 , pp. 720-736
    • Thomas, E.D.1    Ashley, C.A.2    Lochte Jr., H.L.3
  • 5
    • 33646119401 scopus 로고    scopus 로고
    • Hematopoietic stem-cell transplantation
    • Copelan EA. Hematopoietic stem-cell transplantation. N Engl J Med 2006;354:1813-1826.
    • (2006) N Engl J Med , vol.354 , pp. 1813-1826
    • Copelan, E.A.1
  • 6
    • 0016269155 scopus 로고
    • Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo
    • Friedenstein AJ, Chailakhyan RK, Latsinik NV et al. Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo. Transplantation 1974;17:331-340.
    • (1974) Transplantation , vol.17 , pp. 331-340
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Latsinik, N.V.3
  • 7
    • 77952319188 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy: Two steps forward, one step back
    • Ankrum J, Karp JM. Mesenchymal stem cell therapy: Two steps forward, one step back. Trends Mol Med 2010;16:203-209.
    • (2010) Trends Mol Med , vol.16 , pp. 203-209
    • Ankrum, J.1    Karp, J.M.2
  • 8
    • 60849136593 scopus 로고    scopus 로고
    • Mesenchymal stem cell homing: The devil is in the details
    • Karp JM, Leng Teo GS. Mesenchymal stem cell homing: The devil is in the details. Cell Stem cell 2009;4:206-216.
    • (2009) Cell Stem Cell , vol.4 , pp. 206-216
    • Karp, J.M.1    Leng Teo, G.S.2
  • 9
    • 78650176839 scopus 로고    scopus 로고
    • Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors
    • Meyerrose T, Olson S, Pontow S et al. Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors. Adv Drug Deliv Rev 2010;62:1167-1174.
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 1167-1174
    • Meyerrose, T.1    Olson, S.2    Pontow, S.3
  • 10
    • 67149117116 scopus 로고    scopus 로고
    • Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity
    • Capoccia BJ, Robson DL, Levac KD et al. Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity. Blood 2009;113:5340-5351.
    • (2009) Blood , vol.113 , pp. 5340-5351
    • Capoccia, B.J.1    Robson, D.L.2    Levac, K.D.3
  • 12
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • DOI 10.1182/blood-2004-04-1559
    • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005;105:1815-1822. (Pubitemid 40223708)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 14
    • 34748892483 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction: Results from the Stem Cells in Myocardial Infarction (STEMMI) trial
    • DOI 10.1161/CIRCULATIONAHA.106.678649, PII 0000301720070911100004
    • Ripa RS, Haack-Sorensen M, Wang Y et al. Bone marrow derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction: results from the stem cells in myocardial infarction (STEMMI) trial. Circulation 2007;116(11 suppl):I24-I30. (Pubitemid 47480766)
    • (2007) Circulation , vol.116 , Issue.11 SUPPL. 1
    • Ripa, R.S.1    Haack-Sorensen, M.2    Wang, Y.3    Jorgensen, E.4    Mortensen, S.5    Bindslev, L.6    Friis, T.7    Kastrup, J.8
  • 15
    • 78649352832 scopus 로고    scopus 로고
    • Mesenchymal stem cells for the treatment of neurodegenerative disease
    • Joyce N, Annett G, Wirthlin L et al. Mesenchymal stem cells for the treatment of neurodegenerative disease. Regen Med 2010;5:933-946.
    • (2010) Regen Med , vol.5 , pp. 933-946
    • Joyce, N.1    Annett, G.2    Wirthlin, L.3
  • 18
    • 0032877812 scopus 로고    scopus 로고
    • Bone marrow stromal cells as a vehicle for gene transfer
    • DOI 10.1038/sj.gt.3300973
    • Ding L, Lu S, Batchu R et al. Bone marrow stromal cells as a vehicle for gene transfer. Gene Ther 1999;6:1611-1616. (Pubitemid 29465520)
    • (1999) Gene Therapy , vol.6 , Issue.9 , pp. 1611-1616
    • Ding, L.1    Lu, S.2    Batchu, R.B.3    Saylors III, R.L.4    Munshi, N.C.5
  • 19
    • 17344375421 scopus 로고    scopus 로고
    • Mesenchymal stem cells as vehicles for gene delivery
    • Mosca JD, Hendricks JK, Buyaner D et al. Mesenchymal stem cells as vehicles for gene delivery. Clin Orthop Relat Res 2000(379 Suppl):S71-S90.
    • (2000) Clin Orthop Relat Res , Issue.379 SUPPL.
    • Mosca, J.D.1    Hendricks, J.K.2    Buyaner, D.3
  • 20
    • 77956928344 scopus 로고    scopus 로고
    • Transfusion independence and HMGA2 activation after gene therapy of human beta-thalassaemia
    • Cavazzana-Calvo M, Payen E, Negre O et al. Transfusion independence and HMGA2 activation after gene therapy of human beta-thalassaemia. Nature 2010;467:318-322.
    • (2010) Nature , vol.467 , pp. 318-322
    • Cavazzana-Calvo, M.1    Payen, E.2    Negre, O.3
  • 21
    • 43049161115 scopus 로고    scopus 로고
    • Self-renewal and differentiation capacity of young and aged stem cells
    • Roobrouck VD, Ulloa-Montoya F, Verfaillie CM. Self-renewal and differentiation capacity of young and aged stem cells. Exp Cell Res 2008;314:1937-1944.
    • (2008) Exp Cell Res , vol.314 , pp. 1937-1944
    • Roobrouck, V.D.1    Ulloa-Montoya, F.2    Verfaillie, C.M.3
  • 23
    • 37549030199 scopus 로고    scopus 로고
    • Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
    • Hanna J, Wernig M, Markoulaki S et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007;318:1920-1923.
    • (2007) Science , vol.318 , pp. 1920-1923
    • Hanna, J.1    Wernig, M.2    Markoulaki, S.3
  • 24
    • 58249110796 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from a spinal muscular atrophy patient
    • Ebert AD, Yu J, Rose FF, Jr. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009;457:277-280.
    • (2009) Nature , vol.457 , pp. 277-280
    • Ebert, A.D.1    Yu, J.2    Rose Jr., F.F.3
  • 25
    • 50549089957 scopus 로고    scopus 로고
    • Disease-specific induced pluripotent stem cells
    • Park IH, Arora N, Huo H et al. Disease-specific induced pluripotent stem cells. Cell 2008;134:877-886.
    • (2008) Cell , vol.134 , pp. 877-886
    • Park, I.H.1    Arora, N.2    Huo, H.3
  • 26
    • 79952191792 scopus 로고    scopus 로고
    • Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells
    • Kambal A, Mitchell G, Cary W et al. Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells. Mol Ther 2011;19:584-593.
    • (2011) Mol Ther , vol.19 , pp. 584-593
    • Kambal, A.1    Mitchell, G.2    Cary, W.3
  • 27
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • DOI 10.1038/nature05934, PII NATURE05934
    • Okita K, Ichisaka T, Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007;448:313-317. (Pubitemid 47080336)
    • (2007) Nature , vol.448 , Issue.7151 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 29
    • 79952258224 scopus 로고    scopus 로고
    • Somatic coding mutations in human induced pluripotent stem cells
    • Gore A, Li Z, Fung HL et al. Somatic coding mutations in human induced pluripotent stem cells. Nature 2011;471:63-67.
    • (2011) Nature , vol.471 , pp. 63-67
    • Gore, A.1    Li, Z.2    Fung, H.L.3
  • 30
    • 80052282015 scopus 로고    scopus 로고
    • Effects of donor age, gender, and in vitro cellular aging on the phenotypic, functional, and molecular characteristics of mouse bone marrow-derived mesenchymal stem cells
    • Katsara O, Mahaira LG, Iliopoulou EG et al. Effects of donor age, gender, and in vitro cellular aging on the phenotypic, functional, and molecular characteristics of mouse bone marrow-derived mesenchymal stem cells. Stem Cells Dev 2011;20:1549-1561.
    • (2011) Stem Cells Dev , vol.20 , pp. 1549-1561
    • Katsara, O.1    Mahaira, L.G.2    Iliopoulou, E.G.3
  • 31
    • 78650057056 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived mesenchymal progenitors: An overview
    • Clifton, NJ
    • Hematti P. Human embryonic stem cell-derived mesenchymal progenitors: An overview. Methods Mol Biol (Clifton, NJ) 2011;690:163-174.
    • (2011) Methods Mol Biol , vol.690 , pp. 163-174
    • Hematti, P.1
  • 32
    • 79957602085 scopus 로고    scopus 로고
    • Characterization and in vivo testing of mesenchymal stem cells derived from human embryonic stem cells
    • Gruenloh W, Kambal A, Sondergaard C et al. Characterization and in vivo testing of mesenchymal stem cells derived from human embryonic stem cells. Tissue Eng Part A 2011;17:1517-1525.
    • (2011) Tissue Eng Part A , vol.17 , pp. 1517-1525
    • Gruenloh, W.1    Kambal, A.2    Sondergaard, C.3
  • 33
    • 77949350004 scopus 로고    scopus 로고
    • Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice
    • Lian Q, Zhang Y, Zhang J et al. Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice. Circulation 2010;121:1113-1123.
    • (2010) Circulation , vol.121 , pp. 1113-1123
    • Lian, Q.1    Zhang, Y.2    Zhang, J.3
  • 34
    • 80054885259 scopus 로고    scopus 로고
    • Effects on proliferation and differentiation of multipotent bone marrow stromal cells engineered to express growth factors for combined cell and gene therapy
    • in press
    • Fierro F, Kalomoiris S, Sondergaard C et al. Effects on proliferation and differentiation of multipotent bone marrow stromal cells engineered to express growth factors for combined cell and gene therapy. Stem Cells 2011 (in press).
    • (2011) Stem Cells
    • Fierro, F.1    Kalomoiris, S.2    Sondergaard, C.3
  • 35
    • 55049118090 scopus 로고    scopus 로고
    • Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease
    • Meyerrose TE, Roberts M, Ohlemiller KK et al. Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease. Stem Cells 2008;26:1713-1722.
    • (2008) Stem Cells , vol.26 , pp. 1713-1722
    • Meyerrose, T.E.1    Roberts, M.2    Ohlemiller, K.K.3
  • 36
    • 33750081777 scopus 로고    scopus 로고
    • FDA regulation of stem-cell-based therapies
    • DOI 10.1056/NEJMhpr063086
    • Halme DG, Kessler DA. FDA regulation of stem-cell-based therapies. N Engl J Med 2006;355:1730-1735. (Pubitemid 44583964)
    • (2006) New England Journal of Medicine , vol.355 , Issue.16 , pp. 1730-1735
    • Halme, D.G.1    Kessler, D.A.2
  • 37
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa M, Koyanagi M, Tanabe K et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008;26:101-106.
    • (2008) Nat Biotechnol , vol.26 , pp. 101-106
    • Nakagawa, M.1    Koyanagi, M.2    Tanabe, K.3
  • 38
    • 51349090473 scopus 로고    scopus 로고
    • Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCIDX1
    • Hacein-Bey-Abina S, Garrigue A, Wang GP et al. Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCIDX1. J Clin Invest 2008;118:3132-3142.
    • (2008) J Clin Invest , vol.118 , pp. 3132-3142
    • Hacein-Bey-Abina, S.1    Garrigue, A.2    Wang, G.P.3
  • 39
    • 78149482538 scopus 로고    scopus 로고
    • Stem-cell gene therapy for the Wiskott-Aldrich syndrome
    • Boztug K, Schmidt M, Schwarzer A et al. Stem-cell gene therapy for the Wiskott-Aldrich syndrome. N Engl J Med 2010;363:1918-1927.
    • (2010) N Engl J Med , vol.363 , pp. 1918-1927
    • Boztug, K.1    Schmidt, M.2    Schwarzer, A.3
  • 40
    • 59449098985 scopus 로고    scopus 로고
    • Gene therapy for immunodeficiency due to adenosine deaminase deficiency
    • Aiuti A, Cattaneo F, Galimberti S et al. Gene therapy for immunodeficiency due to adenosine deaminase deficiency. N Engl J Med 2009;360:447-458.
    • (2009) N Engl J Med , vol.360 , pp. 447-458
    • Aiuti, A.1    Cattaneo, F.2    Galimberti, S.3
  • 42
    • 79957602085 scopus 로고    scopus 로고
    • Characterization and in vivo testing of mesenchymal stem cells derived from human embryonic stem cells
    • Gruenloh W, Kambal A, Sondergaard C et al. Characterization and in vivo testing of mesenchymal stem cells derived from human embryonic stem cells. Tissue Eng Part A 2011;17:1517-1525.
    • (2011) Tissue Eng Part A , vol.17 , pp. 1517-1525
    • Gruenloh, W.1    Kambal, A.2    Sondergaard, C.3
  • 43
    • 79952899995 scopus 로고    scopus 로고
    • Methods for making induced pluripotent stem cells: Reprogramming a la carte
    • Gonzalez F, Boue S, Izpisua Belmonte JC. Methods for making induced pluripotent stem cells: Reprogramming a la carte. Nat Rev Genet 2011;12:231-242.
    • (2011) Nat Rev Genet , vol.12 , pp. 231-242
    • Gonzalez, F.1    Boue, S.2    Izpisua Belmonte, J.C.3
  • 44
    • 78649647814 scopus 로고    scopus 로고
    • Reprogramming of human primary somatic cells by OCT4 and chemical compounds
    • Zhu S, Li W, Zhou H et al. Reprogramming of human primary somatic cells by OCT4 and chemical compounds. Cell Stem Cell 2010;7:651-655.
    • (2010) Cell Stem Cell , vol.7 , pp. 651-655
    • Zhu, S.1    Li, W.2    Zhou, H.3
  • 45
    • 79952126043 scopus 로고    scopus 로고
    • Copy number variation and selection during reprogramming to pluripotency
    • Hussein SM, Batada NN, Vuoristo S et al. Copy number variation and selection during reprogramming to pluripotency. Nature 2011;471:58-62.
    • (2011) Nature , vol.471 , pp. 58-62
    • Hussein, S.M.1    Batada, N.N.2    Vuoristo, S.3
  • 46
    • 79952264847 scopus 로고    scopus 로고
    • Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
    • Lister R, Pelizzola M, Kida YS et al. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 2011; 471:68-73.
    • (2011) Nature , vol.471 , pp. 68-73
    • Lister, R.1    Pelizzola, M.2    Kida, Y.S.3
  • 47
    • 77957334627 scopus 로고    scopus 로고
    • Identification and classification of chromosomal aberrations in human induced pluripotent stem cells
    • Mayshar Y, Ben-David U, Lavon N et al. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell 2010;7:521-531.
    • (2010) Cell Stem Cell , vol.7 , pp. 521-531
    • Mayshar, Y.1    Ben-David, U.2    Lavon, N.3
  • 48
    • 77957935775 scopus 로고    scopus 로고
    • Geron trial resumes, but standards for stem cell trials remain elusive
    • Strauss S. Geron trial resumes, but standards for stem cell trials remain elusive. Nat Biotechnol 2010;28:989-990.
    • (2010) Nat Biotechnol , vol.28 , pp. 989-990
    • Strauss, S.1
  • 49
    • 13844267152 scopus 로고    scopus 로고
    • Human embryonic stem cells express an immunogenic nonhuman sialic acid
    • DOI 10.1038/nm1181
    • Martin MJ, Muotri A, Gage F et al. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med 2005;11:228-232. (Pubitemid 40321360)
    • (2005) Nature Medicine , vol.11 , Issue.2 , pp. 228-232
    • Martin, M.J.1    Muotri, A.2    Gage, F.3    Varki, A.4
  • 50
    • 78650971216 scopus 로고    scopus 로고
    • Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture
    • Laurent LC, Ulitsky I, Slavin I et al. Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. Cell Stem Cell 2011;8:106-118.
    • (2011) Cell Stem Cell , vol.8 , pp. 106-118
    • Laurent, L.C.1    Ulitsky, I.2    Slavin, I.3
  • 51
    • 78149487692 scopus 로고    scopus 로고
    • Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues
    • Hanna JH, Saha K, Jaenisch R. Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell 2010;143:508-525.
    • (2010) Cell , vol.143 , pp. 508-525
    • Hanna, J.H.1    Saha, K.2    Jaenisch, R.3
  • 52
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • Kim K, Doi A, Wen B et al. Epigenetic memory in induced pluripotent stem cells. Nature 2010;467:285-290.
    • (2010) Nature , vol.467 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3
  • 53
    • 79952900560 scopus 로고    scopus 로고
    • Turning straw into gold: Directing cell fate for regenerative medicine
    • Cohen DE, Melton D. Turning straw into gold: Directing cell fate for regenerative medicine. Nat Rev Genet 2011;12:243-252.
    • (2011) Nat Rev Genet , vol.12 , pp. 243-252
    • Cohen, D.E.1    Melton, D.2
  • 54
    • 61449171881 scopus 로고    scopus 로고
    • Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient
    • Amariglio N, Hirshberg A, Scheithauer BW et al. Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient. PLoS Med 2009;6:e1000029.
    • (2009) PLoS Med , vol.6
    • Amariglio, N.1    Hirshberg, A.2    Scheithauer, B.W.3
  • 55
    • 79151475088 scopus 로고    scopus 로고
    • Cardiac cell therapy: Lessons from clinical trials
    • Menasche P. Cardiac cell therapy: Lessons from clinical trials. J Mol Cell Cardiol 2011;50:258-265.
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 258-265
    • Menasche, P.1
  • 56
    • 79952624644 scopus 로고    scopus 로고
    • Efficacy and safety of ex vivo cultured adult human mesenchymal stem cells (Prochymal) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study
    • Prasad VK, Lucas KG, Kleiner GI et al. Efficacy and safety of ex vivo cultured adult human mesenchymal stem cells (Prochymal) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study. Biol Blood Marrow Transplant 2011;17:534-541.
    • (2011) Biol Blood Marrow Transplant , vol.17 , pp. 534-541
    • Prasad, V.K.1    Lucas, K.G.2    Kleiner, G.I.3
  • 57
    • 78649643642 scopus 로고    scopus 로고
    • MSCs: Biological characteristics, clinical applications and their outstanding concerns
    • Si YL, Zhao YL, Hao HJ et al. MSCs: Biological characteristics, clinical applications and their outstanding concerns. Ageing Res Rev 2011;10:93-103.
    • (2011) Ageing Res Rev , vol.10 , pp. 93-103
    • Si, Y.L.1    Zhao, Y.L.2    Hao, H.J.3
  • 58
    • 79952639223 scopus 로고    scopus 로고
    • Mesenchymal stromal cells for graft-versus-host disease
    • Tolar J, Villeneuve P, Keating A. Mesenchymal stromal cells for graft-versus-host disease. Hum Gene Ther 2011;22:257-262.
    • (2011) Hum Gene Ther , vol.22 , pp. 257-262
    • Tolar, J.1    Villeneuve, P.2    Keating, A.3
  • 59
    • 77955820309 scopus 로고    scopus 로고
    • Concise review: Hitting the right spot with mesenchymal stromal cells
    • Tolar J, Le Blanc K, Keating A et al. Concise review: Hitting the right spot with mesenchymal stromal cells. Stem Cells 2010;28:1446-1555.
    • (2010) Stem Cells , vol.28 , pp. 1446-1555
    • Tolar, J.1    Le Blanc, K.2    Keating, A.3
  • 60
    • 55049084643 scopus 로고    scopus 로고
    • Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells
    • Rosova I, Dao M, Capoccia B et al. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells 2008;26:2173-2182.
    • (2008) Stem Cells , vol.26 , pp. 2173-2182
    • Rosova, I.1    Dao, M.2    Capoccia, B.3
  • 61
    • 70449629693 scopus 로고    scopus 로고
    • Optimizing mesenchymal stem cell-based therapeutics
    • Wagner J, Kean T, Young R et al. Optimizing mesenchymal stem cell-based therapeutics. Curr Opin Biotechnol 2009;20:531-536.
    • (2009) Curr Opin Biotechnol , vol.20 , pp. 531-536
    • Wagner, J.1    Kean, T.2    Young, R.3
  • 62


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.