Designing modulators of dimethylarginine dimethylaminohydrolase (DDAH): A focus on selectivity over arginase

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 27, Issue 1, 2012, Pages 24-28

  Kotthaus, Juerke ^a   Schade, Dennis ^a,b   Kotthaus, Joscha ^a   Clement, Bernd ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b BURNHAM INSTITUTE   (United States)

Author keywords

Arginase; Dimethylarginine dimethylaminohydrolase; L 257; Nitric oxide; Nitric oxide synthase

Indexed keywords

ARGINASE; DIMETHYLARGININASE; ENZYME INHIBITOR; N OMEGA (2 METHOXYETHYL)ARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMIDOHYDROLASES; ARGININE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; MOLECULAR STRUCTURE; ORNITHINE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84855399661     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2011.573480     Document Type: Article

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