Association of SLC38A4 and system a with abnormal fetal birth weight

Experimental and Therapeutic Medicine

Volumn 3, Issue 2, 2012, Pages 309-313

  Li, Zhen ^a   Lai, Guangrui ^b   Deng, Lijun ^a   Han, Yue ^a   Zheng, Danfeng ^a   Song, Weiwei ^a  

^a Departments of Gynaecology and Obstetrics   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Birth weight; Sodium coupled neutral amino acid transport protein 4; Solute carrier family 38 member 4; System a

Indexed keywords

MEMBRANE PROTEIN; MESSENGER RNA; SODIUM COUPLED NEUTRAL AMINO ACID TRANSPORT PROTEIN 4; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; DENSITOMETRY; FEMALE; FETUS; FETUS GROWTH; FETUS WEIGHT; GENETIC CORRELATION; GESTATIONAL AGE; HUMAN; LOW BIRTH WEIGHT; MACROSOMIA; MATERNAL AGE; NEWBORN; PLACENTA; PREGNANCY OUTCOME; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84855382766     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2011.392     Document Type: Article

References (27)

1. Rastogi S, Rastogi R, Rastogi D, Rastogi R, Singh G and Chiappelli F: Evaluating the impact of a pragmatic nutrition awareness program for expectant mothers upon birth weight of the newborn. Evid Based Complement Alternat Med 2011: 185672, 2011.
2. Jaddoe VW and Witteman JC: Hypotheses on the fetal origins of adult diseases: contributions of epidemiological studies. Eur J Epidemiol 21: 91-102, 2006.
3. Ong KK and Dunger DB: Perinatal growth failure: the road to obesity, insulin resistance and cardiovascular disease in adults. Best Pract Res Clin Endocrinol Metab 16: 191-207, 2002.
4. Hochberg Z, Feil R, Constancia M, et al: Child health, developmental plasticity, and epigenetic programming. Endocr Rev 32: 159-224, 2011.
5. Oken E and Gillman MW: Fetal origins of obesity. Obes Res 11: 496-506, 2003.
6. Isles AR and Holland AJ: Imprinted genes and mother-offspring interactions. Early Hum Dev 81: 73-77, 2005.
7. Angiolini E, Fowden A, Coan P, et al: Regulation of placental efficiency for nutrient transport by imprinted genes. Placenta 27: 98-102, 2006.
8. Mackenzie B and Erickson JD: Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family. Pflugers Arch 447: 784-795, 2004.
9. Desforges M, Lacey HA, Glazier JD, et al: SNAT4 isoform of system A amino acid transporter is expressed in human placenta. Am J Physiol Cell Physiol 290: 305-312, 2006.
10. Cramer S, Beveridge M, Kilberg M and Novak D: Physiological importance of system A-mediated amino acid transport to rat fetal development. Am J Physiol Cell Physiol 282: 153-160, 2002.
11. Jansson N, Pettersson J, Haafiz A, et al: Down-regulation of placental transport of amino acidsprecedes the development of intrauterine growth restriction in rats fed a low protein diet. J Physiol 576: 935-946, 2006.
12. Myatt L: Placental adaptive responses and fetal programming. J Physiol 572: 25-30, 2006.
13. Haider BA, Yakoob MY and Bhutta ZA: Effect of multiple micronutrient supplementation during pregnancy on maternal and birth outcomes. BMC Public Health 11: S19, 2011.
14. Jensen RB, Chellakooty M, Vielwerth S, et al: Intrauterine growth retardation and consequences for endocrine and cardiovascular diseases in adult life: does insulin-like growth factor-I play a role? Horm Res 60: 136-148, 2003.
15. Hiden U, Lang U and Desoye G: Fetoplacental disturbances in gestational diabetes mellitus. Gynakol Geburtshilfliche Rundsch 49: 224-229, 2009.
16. Rosario FJ, Jansson N, Kanai Y, et al: Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters. Endocrinology 152: 1119-1129, 2011.
17. Mizuno Y, Sotomaru Y, Katsuzawa Y, et al: Asb4, Ata3, and Dcn are novel imprinted genes identified by high-throughput screening using RIKEN cDNA microarray. Biochem Biophys Res Commun 290: 1499-1505, 2002.
18. Hediger MA, Romero MF, Peng JB, Rolfs A, Takanaga H and Bruford EA: The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins. Pflugers Arch 447: 465-468, 2004.
19. Hay N and Sonenberg N: Upstream and downstream of mTOR. Genes Dev 18: 1926-1945, 2004.
20. Desforges M, Greenwood SL, Glazier JD, Westwood M and Sibley CP: The contribution of SNAT1 to system A amino acid transporter activity in human placental trophoblast. Biochem Biophys Res Commun 398: 130-134, 2010.
21. Jones HN, Jansson T and Powell TL: IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2. Am J Physiol Cell Physiol 297: 1228-1235, 2009.
22. Desforges M, Mynett KJ, Jones RL, et al: The SNAT4 isoform of the system A amino acid transporter is functional in human placental microvillous plasma membrane. J Physiol 587: 61-72, 2009.
23. Johnson LW and Smith CH: Neutral amino acid transport systems of microvillous membrane of human placenta. Am J Physiol 254: 773-780, 1988.
24. Jansson T, Ylven K, Wennergren M and Powell TL: Glucose transport and system A activity in syncytiotrophoblast microvillous and basal plasma membranes in intrauterine growth restriction. Placenta 23: 392-399, 2002.
25. Constancia M, Hemberger M, Hughes J, et al: Placental-specific IGF-II is a major modulator of placental and fetal growth. Nature 417: 945-948, 2002.
26. Constancia M, Angiolini E, Sandoivi I, et al: Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems. Proc Natl Acad Sci USA 102: 19219-19224, 2005.
27. Ornoy A: Prenatal origin of obesity and their complications: Gestational diabetes, maternal overweight and the paradoxical effects of fetal growth restriction and macrosomia. Reprod Toxicol 32: 205-212, 2011.