Lipid lowering effect of Cinnamomum zeylanicum in hyperlipidaemic albino rabbits

Pakistan Journal of Pharmaceutical Sciences

Volumn 25, Issue 1, 2012, Pages 141-147

  Javed, Ijaz ^a   Faisal, Imran ^a   Zia Ur Rahman, ^a   Khan, Muhammad Zargham ^a   Muhammad, Faqir ^a   Aslam, Bilal ^a   Ahmad, Mahmood ^b   Shahzadi, Andleeb ^a  

^a UNIVERSITY OF AGRICULTURE   (Pakistan)

^b THE ISLAMIA UNIVERSITY OF BAHAWALPUR   (Pakistan)

Author keywords

Cinnamomum zeylanicum; Hyperlipidaemic albino rabbits; Lipid lowering effect

Indexed keywords

ANTILIPEMIC AGENT; CHOLESTEROL; CINNAMOMUM ZEYLANICUM EXTRACT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METHANOL; PLANT EXTRACT; SIMVASTATIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BARK; BUTTER; CHOLESTEROL BLOOD LEVEL; CINNAMOMUM ZEYLANICUM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; HYPERLIPIDEMIA; MALE; NONHUMAN; POWDER;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CHOLESTEROL; CINNAMOMUM ZEYLANICUM; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HUMANS; HYPERLIPIDEMIAS; LIPIDS; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS; POWDERS; RABBITS; SIMVASTATIN; TRIGLYCERIDES;

EID: 84855380842     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Agarwal V and Chavan BM (1988). Plant Foods. Hum. Nutr., 38 : 189-197.
2. Alzira A, Carvalho S, Lima UWP and Valiente RA (2004). Statin and fibrate associated myopathy study of eight patients. Arq Neuropsiquiatr, 62: 257-261.
3. Anonymous (1999). The World Health Report. Making a difference. Geneva: World Health Organization; http://www.who.int/whr/1999/en/.
4. Anonymous (2010). Uses of honey and cinnamon and its benefits. http://alislaah4. tripod. com/moreadvices2/id18.htm, date assessed August 31, 2010.
5. Asia Pacific Cohort Studies Collaboration (2004). Serum triglycerides as a risk factor for cardiovascular diseases in the Asia-pacific region. Circulation, 2678-2686.
6. Ballantyne CM, Blazing MA, Hunninghake DB, Davidson MH, Yuan Z, DeLucca P, Ramsey KE, Hustad CM and Palmisano J (2003). Effect on high density lipoprotein cholesterol of maximum dose simvastatin and atorvastatin in patients with hypercholesterolemia: Results of the comparative HDL efficacy and safety study (CHESS). Am. Heart J., 146: 862-869. (Pubitemid 37378576)
7. Barceloux DG (2009). Cinnamon (Cinnamomum Species). Disease-a-Month, 55: 327 335.
8. Bays HE, Moore PB, Drehobl MA, Rosenblatt S, Toth PD, Dujovne CA, Knopp RH, Lipka LJ, LeBeaut AP, Yang B, Mellars LE, Cuffie-Jackson C, Veltri EP and Group ES (2001). Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: Pooled analysis of two phase II studies. Clin. Therapeut., 23: 1209-1230. (Pubitemid 32804115)
9. Bhandari U, Grover JK, Sharma JN (2002). Effect of indeginous drugs on changes in morphology and cholesterol level of aorta in early atherosclerotic progression. Hamdard Med., 4: 56-59.
10. Blume oils on some physiological parameters in streptozotocin induced diabetic rats. Bol. Latinoam. Caribe, 8: 86-96.
11. Blumenthal M (1998). Complete Commission E Monographs. Boston: Integrative Medicine.
12. Broadhurst CL, Polansky MM and Anderson RA (2000). Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J. Agr. Food Chem., 48: 849-852.
13. Choi JS (1991). Antihyperlipidaemic effect of flavonoids from Prunus davidiana. J. Nat. Prod., 54: 218-224.
14. Goyal R, Grewal RB (2003). The influence of Teent (C.decidua) on human plasma triglycerides, total lipids and phospholipids. Nutr. Health, 17: 71-76. (Pubitemid 37026087)
15. Harris PA, Frape DL, Jeffcott LB, Lucas DM, Meyer H, Savage CJ (1998). Equine nutrition and metabolic diseases. In: The Equine Manual, Higgins, AJ and I.M. Wright eds. W.B. Saunders, Philadelphia, USA, pp.123-186.
16. Huang S, Hu S, Shi J and Yang Y (2001). Studies on chemical constituents from the flower of Citrus aurantium [Article in Chinese]. Zhong Yao Cai. 24(12): 865-867.
17. Jain GC, Jhalani S, Agarwal S and Jain K (2007). Hypolipidaemic and antiatherosclerotic effect of Leptadenia pyrotechnica extract in cholesterol fed rabbits. Asian J. Exp. Sci., 21: 115-122.
18. Javed I, Akhtar MS, Rahman ZU, Khaliq T and Ahmad M (1994). Comparative anthalmintic efficacy and safety of Caesalpinia crista seed and Piprazine adipate in chickens with artificially induced Ascaradia galli infection. Acta. Vet. Hungarica., 42: 103-109.
19. Javed I, Iqbal Z, Rahman ZU, Khan FH, Muhammad F, Aslam B and Ali L (2006). Comparative antihyperlipidaemic efficacy of Trachyspermum ammi extracts in albino rabbits. Pakistan Vet. J., 26: 23-29.
20. Javed I, Rahman ZU, Khan MZ, Muhammad F, Aslam B, Iqbal Z, Sultan JI and Ahmad I (2009). Antihyperlipidaemic efficacy of Trachyspermum ammi in albino rabbits. Acta. Vet. Brno., 78: 229-236.
21. Katan MB, Grundy SM, Jones P, Law M, Miettinen T and Paoletti R (2003). Efficacyand safety of plant stanols and sterols in the management of blood cholesterol levels. Mayo Clin. Proc, 78: 965-978. (Pubitemid 36936128)
22. Khan A, Safdar M, Ali KMM, Khattak KN and Anderson RA (2003). Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care, 26: 3215-3218. (Pubitemid 37466877)
23. Murphy JM (1999). Preoperative considerations with herbal medicines. Am. Org. Regist. Nurses J., 69: 173-183.
24. Newman CB, Palmer G, Silbershatz H and Szarek M (2003). Safety of atorvastatin derived from analysis of 44 completed trials in 9416 patients. Am. J. Cardiol., 92: 670-676. (Pubitemid 37103016)
25. Onderoglu S, Sozer S, Erbil KM, Ortac R and Lermioglu F (1999). The evaluation of long-term effects of cinnamon bark and olive leaf on toxicity induced by streptozotocin administration to rats. J. Pharm. Pharmacol., 51: 1305-1312. (Pubitemid 30006471)
26. Prasad K (2005). Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flax seed. Atherosclerosis, 179: 269-275.
27. Purohit A and Daradka HMM (2001). Hypolipidaemic effect of Curcuma loga (Haldi) in rabbits. Hamdard Med., 42: 26-29.
28. Raza JA, Joseph DB and Movahed A (2004). Optimal management of hyperlipidemia in primary prevention of cardiovascular disease. Intern. J. Cardio, 97: 355-366. (Pubitemid 39550681)
29. Singh HB, Srivastava M, Singh AB and Srivastava AK (1995). Cinnamon bark oil, a potent fungitoxicant against fungi causing respiratory tract mycoses. Allergy, 50: 995-999. (Pubitemid 26041848)
30. nd Ed. St. Louis, Mosby, pp.105-127.
31. Stein E (2002). The lower the better? Reviewing the evidence for more aggressive cholesterol reduction and goal attainment. Athero Suppl, 2: 19-25.
32. Vijaimohan K, Jainu M, Sabitha KE, Subramaniyam S, Anandhan C and Shyamaladevi CS (2006). Beneficial effects of alpha linolenic acid rich flax seed oil on growth performance and hepatic cholesterol metabolism in high fat diet fed rat. Life Sci., 79: 448-454. (Pubitemid 43866126)
33. th ed., Cambridge: Cambridge University Press.
34. Zari TA, Allogmani AS (2009). Long term effects of Cinnamomum zeylanicum blume oil on some physiological parameters in streptozotocin diabetic and non-diabetic rats. Bol. Latinoam. Caribe, 8: 266-274.
35. Ziegenfuss TN, Hofheins JE, Mendel RW, Landis J and Anderson RA (2006). Effects of a water soluble cinnamon extract on body composition and features of the metabolic syndrome in prediabetic men and women. J. Intern. Soc. Sports Nutr., 3: 45-53.