Quetiapine- and valproate-associated neutropenia and thrombocytopenia after lamotrigine-induced Steven-Johnson syndrome

Journal of Clinical Psychopharmacology

Volumn 32, Issue 1, 2012, Pages 133-134

  Chang, Li Ren ^a   Chang, Hung Chieh Wu ^a   Lin, Yu Hsuan ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ESTAZOLAM; GLUCOCORTICOID; LAMOTRIGINE; OLANZAPINE; QUETIAPINE; VALPROIC ACID;

ADULT; AGRANULOCYTOSIS; BIPOLAR DEPRESSION; BIPOLAR I DISORDER; CASE REPORT; CERVICAL DYSTONIA; DELIRIUM; DISEASE COURSE; DRUG CROSS REACTIVITY; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; EDEMA; FEMALE; HUMAN; LETTER; LEUKOCYTE COUNT; NEUTROPENIA; NEUTROPHIL COUNT; PRIORITY JOURNAL; PSYCHOMOTOR RETARDATION; STEVENS JOHNSON SYNDROME; SUICIDAL IDEATION; SYMPTOMATOLOGY; THROMBOCYTE COUNT; THROMBOCYTOPENIA;

ANTIMANIC AGENTS; ANTIPSYCHOTIC AGENTS; DIBENZOTHIAZEPINES; HUMANS; MALE; TORTICOLLIS; VALPROIC ACID;

EID: 84855360959     PISSN: 02710749     EISSN: 1533712X     Source Type: Journal    
DOI: 10.1097/JCP.0b013e31823f87e5     Document Type: Letter

References (16)

1. Grunze H, Vieta E, Goodwin GM, et al. The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: update 2010 on the treatment of acute bipolar depression. World J Biol Psychiatry. 2010;11:81-109.
2. Hung SI, Chung WH, Liu ZS, et al. Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese. Pharmacogenomics. 2010;11:349-356.
3. Cowan C, Oakley C. Leukopenia and neutropenia induced by quetiapine. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31:292-294. (Pubitemid 44959256)
4. Blackburn SC, Oliart AD, Garcia Rodriguez LA, et al. Antiepileptics and blood dyscrasias: a cohort study. Pharmacotherapy. 1998;18:1277-1283. (Pubitemid 28533881)
5. Shankar BR. Quetiapine-induced leucopenia and thrombocytopenia. Psychosomatics. 2007;48:530-531. (Pubitemid 350074407)
6. Suppes T, Vieta E, Liu S, et al. Maintenance treatment for patients with bipolar I disorder: results from a North American study of quetiapine in combination with lithium or divalproex (trial 127). Am J Psychiatry. 2009;166:476-488.
7. Winter HR, DeVane CL, Figueroa C, et al. Open-label steady-state pharmacokinetic drug interaction study on co-administered quetiapine fumarate and divalproex sodium in patients with schizophrenia, schizoaffective disorder, or bipolar disorder. Hum Psychopharmacol. 2007;22:469-476. (Pubitemid 47611302)
8. Besag FM, Berry D. Interactions between antiepileptic and antipsychotic drugs. Drug Saf. 2006;29:95-118. (Pubitemid 43213885)
9. Huang CC, Wei IH. Unexpected interaction between quetiapine and valproate in patients with bipolar disorder. Gen Hosp Psychiatry. 2010;32:446.e1-446.e2.
10. Chen CY, Yeh YW, Kuo SC, et al. Pedal edema associated with addition of low-dose quetiapine to valproate treatment in bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2009;33:1551-1552.
11. Habermeyer B, Rabovsky K, Jentzsch C, et al. Cervical dystonia due to interaction of valproic acid and quetiapine. J Clin Psychopharmacol. 2007;27:396-397. (Pubitemid 47075514)
12. Nair P, Lippmann S. Is leukopenia associated with divalproex and/or quetiapine? Psychosomatics. 2005;46:188-189. (Pubitemid 41071505)
13. Aster RH, Bougie DW. Drug-induced immune thrombocytopenia. N Engl J Med. 2007;357:580-587. (Pubitemid 47236283)
14. Rahman A, Mican LM, Fischer C, et al. Evaluating the incidence of leukopenia and neutropenia with valproate, quetiapine, or the combination in children and adolescents. Ann Pharmacother. 2009;43:822-830.
15. Aichhorn W, Marksteiner J, Walch T, et al. Influence of age, gender, body weight and valproate comedication on quetiapine plasma concentrations. Int Clin Psychopharmacol. 2006;21:81-85. (Pubitemid 43740314)
16. Romano A, Gueant-Rodriguez RM, Viola M, et al. Cross-reactivity among drugs: clinical problems. Toxicology. 2005;209:169-179. (Pubitemid 40568646)