Unexpected interaction between quetiapine and valproate in patients with bipolar disorder

General Hospital Psychiatry

Volumn 32, Issue 4, 2010, Pages 446.e1-446.e2

  Huang, Chih Chia ^a,b   Wei, I Hua ^b  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Bipolar; Delirium; Lithium intoxication; Quetiapine; Valproate

Indexed keywords

HALOPERIDOL; LITHIUM SALT; QUETIAPINE; SERTRALINE; VALPROIC ACID; DIBENZOTHIAZEPINE DERIVATIVE;

ADULT; AGITATION; ARTICLE; AUDITORY HALLUCINATION; BIPOLAR DISORDER; CASE REPORT; CONFUSION; DELIRIUM; DEPRESSION; DISORIENTATION; DRUG BLOOD LEVEL; DRUG DOSE TITRATION; DRUG INTOXICATION; DRUG OVERDOSE; DRUG POTENTIATION; DRUG WITHDRAWAL; FEMALE; HUMAN; KIDNEY FAILURE; MALE; MENTAL INSTABILITY; VISUAL HALLUCINATION; CHEMICALLY INDUCED; DRUG COMBINATION; DRUG INTERACTION; MIDDLE AGED;

BIPOLAR DISORDER; DELIRIUM; DIBENZOTHIAZEPINES; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; MIDDLE AGED; VALPROIC ACID;

EID: 77954620034     PISSN: 01638343     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.genhosppsych.2009.06.005     Document Type: Article

References (9)

1. Gareri P., De Fazio P., Cotroneo A., Lacava R., Gallelli L., De Fazio S., et al. Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient. Arch Gerontol Geriatr 2007, 44:199-206.
2. Goldstein J.M., Brecher M. Clarification of anticholinergic effects of quetiapine. J Clin Psychiatry 2000, 61:680.
3. Tariot P.N., Ismail M.S. Use of quetiapine in elderly patients. J Clin Psychiatry 2002, 63:21-26.
4. Chew M.L., Mulsant B.H., Pollock B.G., Lehman M.E., Greenspan A., Kirshner M.A., et al. A model of anticholinergic activity of atypical antipsychotic medications. Schizophr Res 2006, 88:63-72.
5. Chew M.L., Mulsant B.H., Pollock B.G., Lehman M.E., Greenspan A., Mahmoud R.A., et al. Anticholinergic activity of 107 medications commonly used by older adults. J Am Geriatr Soc 2008, 56:1333-1341.
6. Balit C.R., Isbister G.K., Hackett L.P., Whyte I.M. Quetiapine poisoning: a case series. Ann Emerg Med 2003, 42:751-758.
7. Sim F.H., Brunet D.G., Conacher G.N. Quetiapine associated with acute mental status changes. Can J Psychiatry 2000, 45:299.
8. Thyrum P.T., Wong Y.W., Yeh C. Single-dose pharmacokinetics of quetiapine in subjects with renal or hepatic impairment. Prog Neuropsychopharmacol Biol Psychiatry 2000, 24:521-533.
9. Aichhorn W., Marksteiner J., Walch T., et al. Influence of age, gender, body weight and valproate comedication on quetiapine plasma concentrations. Int Clin Psychopharmacol. 2006, 21:81-85.