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Volumn 881-882, Issue , 2012, Pages 34-41
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Development and validation of a sensitive solid-phase-extraction (SPE) method using high-performance liquid chromatography/tandem mass spectrometry (LC-MS/MS) for determination of risedronate concentrations in human plasma
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Author keywords
Bisphosphonate; Derivatization; Liquid chromatography tandem mass spectrometry (LC MS MS); Plasma; Quantification; Risedronate; Solid phase extraction (SPE); Trimethylsilyldiazomethane
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Indexed keywords
BISPHOSPHONATES;
DERIVATIZATIONS;
LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY (LC-MS/MS);
QUANTIFICATION;
RISEDRONATE;
SOLID PHASE EXTRACTION (SPE);
TRIMETHYLSILYLDIAZOMETHANE;
ACETONITRILE;
AMMONIUM COMPOUNDS;
BIOCHEMISTRY;
CALIBRATION;
CHROMATOGRAPHY;
LIQUIDS;
MASS SPECTROMETRY;
ORGANIC ACIDS;
PLASMA (HUMAN);
PLASMAS;
STANDARDS;
EXTRACTION;
ACETONITRILE;
AMMONIUM ACETATE;
IBUPROFEN;
PARACETAMOL;
PHOSPHONIC ACID DERIVATIVE;
RISEDRONIC ACID;
ACCURACY;
ARTICLE;
CALIBRATION;
COLLISIONALLY ACTIVATED DISSOCIATION;
DILUTION;
FLOW RATE;
FREEZE THAWING;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN EXPERIMENT;
HUMAN TISSUE;
INSTRUMENT VALIDATION;
LIMIT OF QUANTITATION;
NORMAL HUMAN;
PLASMA;
PRIORITY JOURNAL;
ROOM TEMPERATURE;
SENSITIVITY ANALYSIS;
SINGLE DRUG DOSE;
SOLID PHASE EXTRACTION;
STRUCTURE ACTIVITY RELATION;
TANDEM MASS SPECTROMETRY;
THERMOSTABILITY;
ACETAMINOPHEN;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DIAZOMETHANE;
DRUG STABILITY;
ETIDRONIC ACID;
HEMOLYSIS;
HUMANS;
IBUPROFEN;
REGRESSION ANALYSIS;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
SOLID PHASE EXTRACTION;
TANDEM MASS SPECTROMETRY;
TRIMETHYLSILYL COMPOUNDS;
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EID: 84855347325
PISSN: 15700232
EISSN: 1873376X
Source Type: Journal
DOI: 10.1016/j.jchromb.2011.11.031 Document Type: Article |
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Times cited : (21)
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References (16)
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