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Volumn 107, Issue 1, 2012, Pages 88-98

Platelet soluble CD40l and matrix metalloproteinase 9 activity are proinflammatory mediators in behçet disease patients

Author keywords

Beh et disease; CD40l; Matrix metalloproteinase 9; MEG 01 cells; Platelets

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; GELATINASE A; GELATINASE B;

EID: 84855324263     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH11-08-0556     Document Type: Article
Times cited : (25)

References (56)
  • 2
    • 0027740303 scopus 로고
    • Overproduction of monocyte derived tumor necrosis factor alpha, interleukin (IL) 6, IL-8 and increased neutrophil superoxide generation in Behcet's disease. A comparative study with familial Mediterranean fever and healthy subjects
    • Mege JL, Dilsen N, Sanguedolce V, et al. Overproduction of monocyte derived tumor necrosis factor alpha, interleukin (IL) 6, IL-8 and increased neutrophil superoxide generation in Behcet's disease. A comparative study with familial Mediterranean fever and healthy subjects. J Rheumatol 1993; 20: 1544-1549.
    • (1993) J Rheumatol , vol.20 , pp. 1544-1549
    • Mege, J.L.1    Dilsen, N.2    Sanguedolce, V.3
  • 3
    • 0034757551 scopus 로고    scopus 로고
    • Behcet's disease: Infectious aetiology, new autoantigens, and HLA-B51
    • Direskeneli H. Behcet's disease: infectious aetiology, new autoantigens, and HLA-B51. Ann Rheum Dis 2001; 60: 996-1002.
    • (2001) Ann Rheum Dis , vol.60 , pp. 996-1002
    • Direskeneli, H.1
  • 4
    • 33751435160 scopus 로고    scopus 로고
    • Autoimmunity vs autoinflammation in Behcet's disease: Do we oversimplify a complex disorder?
    • Direskeneli H. Autoimmunity vs autoinflammation in Behcet's disease: do we oversimplify a complex disorder? Rheumatology 2006; 45: 1461-1465.
    • (2006) Rheumatology , vol.45 , pp. 1461-1465
    • Direskeneli, H.1
  • 5
    • 0035180028 scopus 로고    scopus 로고
    • Inflammatory role of platelets in acute coronary syndromes
    • Aukrust P, Waehre T, Damås JK, et al. Inflammatory role of platelets in acute coronary syndromes. Heart 2001; 86: 605-606.
    • (2001) Heart , vol.86 , pp. 605-606
    • Aukrust, P.1    Waehre, T.2    Damås, J.K.3
  • 6
    • 0141763768 scopus 로고    scopus 로고
    • Membrane-associated CD40L and sCD40L in atherotrombotic disease
    • Anand SX, Viles-Gonzalez JF, Badimón JJ, et al. Membrane-associated CD40L and sCD40L in atherotrombotic disease. Thromb Haemost. 2003; 90: 377-384.
    • (2003) Thromb Haemost , vol.90 , pp. 377-384
    • Anand, S.X.1    Viles-Gonzalez, J.F.2    Badimón, J.J.3
  • 7
    • 67649672271 scopus 로고    scopus 로고
    • Matrix metalloproteinase 9 is involved in Crohn's disease-associated platelet hyperactivation through the release of soluble CD40 ligand
    • Menchén L, Marín-Jiménez I, Arias-Salgado EG, et al. Matrix metalloproteinase 9 is involved in Crohn's disease-associated platelet hyperactivation through the release of soluble CD40 ligand. Gut 2009; 58: 920-928.
    • (2009) Gut , vol.58 , pp. 920-928
    • Menchén, L.1    Marín-Jiménez, I.2    Arias-Salgado, E.G.3
  • 8
    • 77954482405 scopus 로고    scopus 로고
    • CD40 ligand shedding is regulated by interaction between matrix metalloproteinase-2 and platelet integrin alpha(IIb)beta(3)
    • Choi WS, Jeon OH, Kim DS. CD40 ligand shedding is regulated by interaction between matrix metalloproteinase-2 and platelet integrin alpha(IIb)beta(3). J Thromb Haemost 2010; 8: 1364-1371.
    • (2010) J Thromb Haemost , vol.8 , pp. 1364-1371
    • Choi, W.S.1    Jeon, O.H.2    Kim, D.S.3
  • 9
    • 70350447306 scopus 로고    scopus 로고
    • The multi-functionality of CD40L and its receptor CD40 in atherosclerosis
    • Lievens D, Eijgelaar WJ, Biessen EA, et al. The multi-functionality of CD40L and its receptor CD40 in atherosclerosis. Thromb Haemost 2009; 102: 206-214.
    • (2009) Thromb Haemost , vol.102 , pp. 206-214
    • Lievens, D.1    Eijgelaar, W.J.2    Biessen, E.A.3
  • 10
    • 78549272749 scopus 로고    scopus 로고
    • Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis
    • Lievens D, Zernecke A, Seijkens T et al. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood 2010; 116: 4317-4327.
    • (2010) Blood , vol.116 , pp. 4317-4327
    • Lievens, D.1    Zernecke, A.2    Seijkens, T.3
  • 11
    • 77952013973 scopus 로고    scopus 로고
    • CD40L induces inflammation and adipogenesis in adipose cells--a potential link between metabolic and cardiovascular disease
    • Missiou A, Wolf D, Platzer I, et al. CD40L induces inflammation and adipogenesis in adipose cells--a potential link between metabolic and cardiovascular disease. Thromb Haemost 2010; 103: 788-796.
    • (2010) Thromb Haemost , vol.103 , pp. 788-796
    • Missiou, A.1    Wolf, D.2    Platzer, I.3
  • 12
    • 80052971178 scopus 로고    scopus 로고
    • CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice
    • Poggi M, Engel D, Christ A, et al. CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice. Arterioscler Thromb Vasc Biol 2011; 31: 2251-2260.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2251-2260
    • Poggi, M.1    Engel, D.2    Christ, A.3
  • 13
    • 0037143597 scopus 로고    scopus 로고
    • Platelet-derived CD40L: The switchhitting player of cardiovascular disease
    • Andre P, Nannizzi-Alaimo L, Prasad SK et al. Platelet-derived CD40L: the switchhitting player of cardiovascular disease. Circulation 2002; 106: 896-899.
    • (2002) Circulation , vol.106 , pp. 896-899
    • Andre, P.1    Nannizzi-Alaimo, L.2    Prasad, S.K.3
  • 14
    • 0344850187 scopus 로고    scopus 로고
    • Enhanced levels of soluble and membranebound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes
    • Aukrust P, Müller F, Ueland T, et al. Enhanced levels of soluble and membranebound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes. Circulation 1999; 100: 614-620.
    • (1999) Circulation , vol.100 , pp. 614-620
    • Aukrust, P.1    Müller, F.2    Ueland, T.3
  • 15
    • 0035183844 scopus 로고    scopus 로고
    • Patients with acute coronary syndromes express enhanced CD40 ligand/CD154 on platelets
    • Garlichs CD, Eskafi S, Raaz D, et al. Patients with acute coronary syndromes express enhanced CD40 ligand/CD154 on platelets. Heart 2001; 86: 649-655.
    • (2001) Heart , vol.86 , pp. 649-655
    • Garlichs, C.D.1    Eskafi, S.2    Raaz, D.3
  • 16
    • 0037129901 scopus 로고    scopus 로고
    • Cardiopulmonary bypass induces release of soluble CD40 ligand
    • Nannizzi-Alaimo L, Rubenstein MH, Alves VL, et al. Cardiopulmonary bypass induces release of soluble CD40 ligand. Circulation 2002; 105: 2849-2854.
    • (2002) Circulation , vol.105 , pp. 2849-2854
    • Nannizzi-Alaimo, L.1    Rubenstein, M.H.2    Alves, V.L.3
  • 17
    • 0032742987 scopus 로고    scopus 로고
    • The soluble CD40 ligand sCD154 in systemic lupus erythematosus
    • Kato K, Santana-Sahagún E, Rassenti LZ, et al. The soluble CD40 ligand sCD154 in systemic lupus erythematosus. J Clin Invest 1999; 104: 947-955.
    • (1999) J Clin Invest , vol.104 , pp. 947-955
    • Kato, K.1    Santana-Sahagún, E.2    Rassenti, L.Z.3
  • 18
    • 2942666368 scopus 로고    scopus 로고
    • Platelets in inflammatory bowel disease: Clinical, pathogenic, and therapeutic implications
    • Danese S, de la Motte C, Fiocchi C. Platelets in inflammatory bowel disease: clinical, pathogenic, and therapeutic implications. Am J Gastroenterol 2004; 99: 938-945.
    • (2004) Am J Gastroenterol , vol.99 , pp. 938-945
    • Danese, S.1    de la Motte, C.2    Fiocchi, C.3
  • 19
    • 0025360899 scopus 로고
    • Criteria for diagnosis of Behçet ́s disease
    • International Study Group for Behçet's disease
    • International Study Group for Behçet's disease. Criteria for diagnosis of Behçet ́s disease. Lancet 1990; 335: 1078-1080.
    • (1990) Lancet , vol.335 , pp. 1078-1080
  • 20
    • 0033175977 scopus 로고    scopus 로고
    • Behçet's disease: Evaluation of a new instrument to measure clinical activity
    • Bhakta BB, Brennan P, James TE, et al. Behçet's disease: evaluation of a new instrument to measure clinical activity. Rheumatology 1999; 38: 728-733.
    • (1999) Rheumatology , vol.38 , pp. 728-733
    • Bhakta, B.B.1    Brennan, P.2    James, T.E.3
  • 21
    • 0022353446 scopus 로고
    • Establishment of a novel human megakaryoblastic leukemia cell line, MEG-01, with positive Philadelphia chromosome
    • Ogura M, Morishima Y, Ohno R, et al. Establishment of a novel human megakaryoblastic leukemia cell line, MEG-01, with positive Philadelphia chromosome. Blood 1985; 66: 1384-1392.
    • (1985) Blood , vol.66 , pp. 1384-1392
    • Ogura, M.1    Morishima, Y.2    Ohno, R.3
  • 22
    • 0036130828 scopus 로고    scopus 로고
    • CD40L stabilizes arterial thrombi by a beta3 integrin--dependent mechanism
    • André P, Prasad KS, Denis CV, et al. CD40L stabilizes arterial thrombi by a beta3 integrin--dependent mechanism. Nat Med 2002; 8: 247-252.
    • (2002) Nat Med , vol.8 , pp. 247-252
    • André, P.1    Prasad, K.S.2    Denis, C.V.3
  • 23
    • 2942546273 scopus 로고    scopus 로고
    • Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization
    • Furman MI, Krueger LA, Linden MD, et al. Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization. J Am Coll Cardiol 2004; 43: 2319-2325.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 2319-2325
    • Furman, M.I.1    Krueger, L.A.2    Linden, M.D.3
  • 24
    • 0026609764 scopus 로고
    • Vascular involvement in BD Behçet's disease
    • Koç Y, Güllü I, Akpek G, et al. Vascular involvement in BD Behçet's disease. J Rheumatol 1992; 19: 402-410.
    • (1992) J Rheumatol , vol.19 , pp. 402-410
    • Koç, Y.1    Güllü, I.2    Akpek, G.3
  • 26
    • 35448929936 scopus 로고    scopus 로고
    • Serum MMP-2 and MMP-9 In Patients With Behçet's Disease: Do their Higher Levels Correlate to Vasculo-Behçet's Disease Associated With Aneurysm Formation?
    • Pay S, Abbasov T, Erdem H, et al. Serum MMP-2 and MMP-9 in patients with Behçet's disease: do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation? clin exp rheumatol 2007; 25: s70-75.
    • (2007) Clin Exp Rheumatol , vol.25
    • Pay, S.1    Abbasov, T.2    Erdem, H.3
  • 27
    • 57149139697 scopus 로고    scopus 로고
    • Interphotoreceptor retinoid-binding protein as biomarker in systemic autoimmunity with eye inflictions
    • Descamps FJ, Kangave D, Cauwe B, et al. Interphotoreceptor retinoid-binding protein as biomarker in systemic autoimmunity with eye inflictions. J Cell Mol Med 2008; 12: 2449-2456.
    • (2008) J Cell Mol Med , vol.12 , pp. 2449-2456
    • Descamps, F.J.1    Kangave, D.2    Cauwe, B.3
  • 28
    • 27644529731 scopus 로고    scopus 로고
    • Plasma, serum, and platelet expression of CD40 ligand in adults with cardiovascular disease
    • Mason PJ, Chakrabarti S, Albers AA, et al. Plasma, serum, and platelet expression of CD40 ligand in adults with cardiovascular disease. Am J Cardiol 2005; 96: 1365-1369.
    • (2005) Am J Cardiol , vol.96 , pp. 1365-1369
    • Mason, P.J.1    Chakrabarti, S.2    Albers, A.A.3
  • 29
    • 0036529828 scopus 로고    scopus 로고
    • Increased soluble and platelet-associated CD40 ligand in essential thrombocythemia and reactive thrombocytosis
    • Viallard JF, Solanilla A, Gauthier B, et al. Increased soluble and platelet-associated CD40 ligand in essential thrombocythemia and reactive thrombocytosis. Blood 2002; 99: 2612-2614.
    • (2002) Blood , vol.99 , pp. 2612-2614
    • Viallard, J.F.1    Solanilla, A.2    Gauthier, B.3
  • 30
    • 70449650552 scopus 로고    scopus 로고
    • Translating molecular medicine into clinical tools: Doomed to fail by neglecting basic preanalytical principles
    • Jung K, Mannello F, Lein M. Translating molecular medicine into clinical tools: doomed to fail by neglecting basic preanalytical principles. J Transl Med 2009; 7: 87.
    • (2009) J Transl Med , vol.7 , pp. 87
    • Jung, K.1    Mannello, F.2    Lein, M.3
  • 31
    • 33845749224 scopus 로고    scopus 로고
    • Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma
    • Gerlach RF, Demacq C, Jung K, et al. Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma. Clin Biochem 2007; 40: 119-123.
    • (2007) Clin Biochem , vol.40 , pp. 119-123
    • Gerlach, R.F.1    Demacq, C.2    Jung, K.3
  • 32
    • 43449116076 scopus 로고    scopus 로고
    • Fibrinolytic inhibitor levels and polymorphisms in Behçet disease and their association with thrombosis
    • Ricart JM, Ramón LA, Vayá A, et al. Fibrinolytic inhibitor levels and polymorphisms in Behçet disease and their association with thrombosis. Br J Haematol 2008; 141: 716-719.
    • (2008) Br J Haematol , vol.141 , pp. 716-719
    • Ricart, J.M.1    Ramón, L.A.2    Vayá, A.3
  • 33
    • 33644790123 scopus 로고    scopus 로고
    • Fibrinolytic activity and D-dimer levels in Behçet's syndrome
    • Yurdakul S, Hekim N, Soysal T, et al. Fibrinolytic activity and D-dimer levels in Behçet's syndrome. Clin Exp Rheumatol 2005; 23: S53-58.
    • (2005) Clin Exp Rheumatol , vol.23
    • Yurdakul, S.1    Hekim, N.2    Soysal, T.3
  • 34
    • 33748485340 scopus 로고    scopus 로고
    • Circulated activated platelets and increased platelet reactivity in patients with Behçet's disease
    • Akar S, Ozcan MA, Ates H et al. Circulated activated platelets and increased platelet reactivity in patients with Behçet's disease. Clin Appl Thromb Hemost 2006; 12: 451-457.
    • (2006) Clin Appl Thromb Hemost , vol.12 , pp. 451-457
    • Akar, S.1    Ozcan, M.A.2    Ates, H.3
  • 35
    • 40649099567 scopus 로고    scopus 로고
    • Platelet activation and red blood cell phosphatidylserine exposure evaluated by flow cytometry in patients with Behçet's disease: Are they related to thrombotic events?
    • Martínez M, Ricart JM, Ruiz-Aja S et al. Platelet activation and red blood cell phosphatidylserine exposure evaluated by flow cytometry in patients with Behçet's disease: are they related to thrombotic events? Pathophysiol Haemost Thromb 2007; 36: 18-22.
    • (2007) Pathophysiol Haemost Thromb , vol.36 , pp. 18-22
    • Martínez, M.1    Ricart, J.M.2    Ruiz-Aja, S.3
  • 36
    • 20444490454 scopus 로고    scopus 로고
    • Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products
    • Varo N, Libby P, Nuzzo R, et al. Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products. Diab Vasc Dis Res 2005, 2: 81-87.
    • (2005) Diab Vasc Dis Res , vol.2 , pp. 81-87
    • Varo, N.1    Libby, P.2    Nuzzo, R.3
  • 37
    • 68049112397 scopus 로고    scopus 로고
    • Oxidative stress and inflammatory process in patients with atrial fibrillation: The role of left atrium distension
    • Tousoulis D, Zisimos K, Antoniades C, et al. Oxidative stress and inflammatory process in patients with atrial fibrillation: The role of left atrium distension. Int J Cardiol 2009; 136: 258-262.
    • (2009) Int J Cardiol , vol.136 , pp. 258-262
    • Tousoulis, D.1    Zisimos, K.2    Antoniades, C.3
  • 38
    • 33747361307 scopus 로고    scopus 로고
    • Soluble CD40 ligand and interleukin-6 in the coronary circulation after acute myocardial infarction
    • Ohashi Y, Kawashima S, Mori T. Soluble CD40 ligand and interleukin-6 in the coronary circulation after acute myocardial infarction. Int J Cardiol 2006; 112: 52-58.
    • (2006) Int J Cardiol , vol.112 , pp. 52-58
    • Ohashi, Y.1    Kawashima, S.2    Mori, T.3
  • 39
    • 0035883087 scopus 로고    scopus 로고
    • The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40
    • Henn V, Steinbach S, Buchner K, et al. The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. Blood 2001; 98: 1047-1054.
    • (2001) Blood , vol.98 , pp. 1047-1054
    • Henn, V.1    Steinbach, S.2    Buchner, K.3
  • 40
    • 54049156519 scopus 로고    scopus 로고
    • Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells
    • Chen C, Chai H, Wang X. Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells. Blood 2008; 112: 3205-3216.
    • (2008) Blood , vol.112 , pp. 3205-3216
    • Chen, C.1    Chai, H.2    Wang, X.3
  • 41
    • 0033257535 scopus 로고    scopus 로고
    • Gammadelta T cells in Behçet's disease (BD) and recurrent aphthous stomatitis (RAS)
    • Freysdottir J, Lau S, Fortune F. Gammadelta T cells in Behçet's disease (BD) and recurrent aphthous stomatitis (RAS). Clin Exp Immunol 1999; 118: 451-457.
    • (1999) Clin Exp Immunol , vol.118 , pp. 451-457
    • Freysdottir, J.1    Lau, S.2    Fortune, F.3
  • 42
    • 0036351437 scopus 로고    scopus 로고
    • Cytokine profile in Behçet's disease patients. Relationship with disease activity
    • Hamzaoui K, Hamzaoui A, Guemira F, et al. Cytokine profile in Behçet's disease patients. Relationship with disease activity. Scand J Rheumatol 2002; 31: 205-210.
    • (2002) Scand J Rheumatol , vol.31 , pp. 205-210
    • Hamzaoui, K.1    Hamzaoui, A.2    Guemira, F.3
  • 43
    • 77953694980 scopus 로고    scopus 로고
    • Therapeutic interventions targeting CD40L (CD154) and CD40: The Opportunities and Challenges
    • Law CL, Grewal IS. Therapeutic interventions targeting CD40L (CD154) and CD40: The Opportunities and Challenges. Adv Exp Med Biol 2009; 647: 8-36.
    • (2009) Adv Exp Med Biol , vol.647 , pp. 8-36
    • Law, C.L.1    Grewal, I.S.2
  • 44
    • 0037333857 scopus 로고    scopus 로고
    • A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis
    • Boumpas DT, Furie R, Manzi S, et al. A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis. Arthritis Rheum 2003; 48: 719-727.
    • (2003) Arthritis Rheum , vol.48 , pp. 719-727
    • Boumpas, D.T.1    Furie, R.2    Manzi, S.3
  • 45
    • 0342872046 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: A role for CD40 signaling in plaque rupture?
    • Schönbeck U, Mach F, Sukhova GK, et al. Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture? Circ Res 1997; 81: 448-454.
    • (1997) Circ Res , vol.81 , pp. 448-454
    • Schönbeck, U.1    Mach, F.2    Sukhova, G.K.3
  • 46
    • 42049091649 scopus 로고    scopus 로고
    • CD40 ligand promotes Mac-1 expression, leukocyte recruitment, and neointima formation after vascular injury
    • Li G, Sanders JM, Bevard MH, et al. CD40 ligand promotes Mac-1 expression, leukocyte recruitment, and neointima formation after vascular injury. Am J Pathol 2008; 172: 1141-1152.
    • (2008) Am J Pathol , vol.172 , pp. 1141-1152
    • Li, G.1    Sanders, J.M.2    Bevard, M.H.3
  • 47
    • 0035879312 scopus 로고    scopus 로고
    • CD40L induces matrix-metalloproteinase- 9 but not tissue inhibitor of metalloproteinases-1 in cervical carcinoma cells: Imbalance between NF-kappaB and STAT3 activation
    • Smola-Hess S, Schnitzler R, Hadaschik D, et al. CD40L induces matrix-metalloproteinase- 9 but not tissue inhibitor of metalloproteinases-1 in cervical carcinoma cells: imbalance between NF-kappaB and STAT3 activation. Exp Cell Res 2001; 267: 205-215.
    • (2001) Exp Cell Res , vol.267 , pp. 205-215
    • Smola-Hess, S.1    Schnitzler, R.2    Hadaschik, D.3
  • 48
    • 0031848157 scopus 로고    scopus 로고
    • Expression of functional CD40 on human osteosarcoma and Ewing's sarcoma cells
    • Lollini PL, Landuzzi L, Frabetti F, et al. Expression of functional CD40 on human osteosarcoma and Ewing's sarcoma cells. Clin Cancer Res 1998; 4: 1843-1849.
    • (1998) Clin Cancer Res , vol.4 , pp. 1843-1849
    • Lollini, P.L.1    Landuzzi, L.2    Frabetti, F.3
  • 49
    • 0344699318 scopus 로고    scopus 로고
    • T lymphocytes induce endothelial cell matrix metalloproteinase expression by a CD40L-dependent mechanism: Implications for tubule formation
    • Mach F, Schönbeck U, Fabunmi RP, et al. T lymphocytes induce endothelial cell matrix metalloproteinase expression by a CD40L-dependent mechanism: implications for tubule formation. Am J Pathol 1999; 154: 229-238.
    • (1999) Am J Pathol , vol.154 , pp. 229-238
    • Mach, F.1    Schönbeck, U.2    Fabunmi, R.P.3
  • 51
    • 0035075438 scopus 로고    scopus 로고
    • Platelet CD40 ligand (CD40L)-subcellular localization, regulation of expression, and inhibition by clopidogrel
    • Hermann A, Rauch BH, Braun M, et al. Platelet CD40 ligand (CD40L)-subcellular localization, regulation of expression, and inhibition by clopidogrel. Platelets 2001; 12: 74-82.
    • (2001) Platelets , vol.12 , pp. 74-82
    • Hermann, A.1    Rauch, B.H.2    Braun, M.3
  • 52
    • 80051907306 scopus 로고    scopus 로고
    • Megakaryocytes differentially sort mRNAs for matrix metalloproteinases and their inhibitors into platelets: A mechanism for regulating synthetic events
    • Cecchetti L, Tolley ND, Michetti N, et al. Megakaryocytes differentially sort mRNAs for matrix metalloproteinases and their inhibitors into platelets: a mechanism for regulating synthetic events. Blood 2011; 118: 1903-1911.
    • (2011) Blood , vol.118 , pp. 1903-1911
    • Cecchetti, L.1    Tolley, N.D.2    Michetti, N.3
  • 53
    • 0032779157 scopus 로고    scopus 로고
    • Inhibition of the CD40 pathway of monocyte activation by triazolopyrimidine
    • Zhou L, Ismaili J, Stordeur P, et al. Inhibition of the CD40 pathway of monocyte activation by triazolopyrimidine. Clin Immunol 1999; 93: 232-238.
    • (1999) Clin Immunol , vol.93 , pp. 232-238
    • Zhou, L.1    Ismaili, J.2    Stordeur, P.3
  • 54
    • 2942545917 scopus 로고    scopus 로고
    • Trapidil inhibits monocyte CD40 expression by preventing IFN-gamma-induced STAT1 S727 phosphorylation
    • Zhou L, Schandené L, Mordvinov VA, et al. Trapidil inhibits monocyte CD40 expression by preventing IFN-gamma-induced STAT1 S727 phosphorylation. Int Immunopharmacol 2004; 4: 863-871.
    • (2004) Int Immunopharmacol , vol.4 , pp. 863-871
    • Zhou, L.1    Schandené, L.2    Mordvinov, V.A.3
  • 55
    • 0035850681 scopus 로고    scopus 로고
    • Effects of trapidil on effector functions of monocytes related to atherosclerotic plaque
    • Kato Y, Tsuda T, Hosaka Y, et al. Effects of trapidil on effector functions of monocytes related to atherosclerotic plaque. Eur J Pharmacol 2001; 428: 371-379.
    • (2001) Eur J Pharmacol , vol.428 , pp. 371-379
    • Kato, Y.1    Tsuda, T.2    Hosaka, Y.3
  • 56
    • 77149136451 scopus 로고    scopus 로고
    • Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile
    • Lutgens E, Lievens D, Beckers L, et al. Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. J Exp Med 2010; 207: 391-404.
    • (2010) J Exp Med , vol.207 , pp. 391-404
    • Lutgens, E.1    Lievens, D.2    Beckers, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.