Liposomal delivery system for topical anaesthesia of the palatal mucosa

British Journal of Oral and Maxillofacial Surgery

Volumn 50, Issue 1, 2012, Pages 60-64

  Franz Montan, M ^a   De Paula, E ^a   Groppo, F C ^a   Silva, A L R ^a   Ranali, J ^a   Volpato, M C ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Anaesthetic efficacy; In vivo; Local anaesthetics; Oral mucosa; Ropivacaine

Indexed keywords

EMLA; LIDOCAINE; PLACEBO; PRILOCAINE; ROPIVACAINE;

ADULT; ARTICLE; CHEEK MUCOSA; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ENCAPSULATION; FEMALE; HUMAN; LOCAL ANESTHESIA; MALE; NEEDLE; PAIN; SINGLE BLIND PROCEDURE; TOPICAL ANESTHESIA; VISUAL ANALOG SCALE; VOLUNTEER;

ADMINISTRATION, TOPICAL; ADULT; AMIDES; ANESTHESIA, DENTAL; ANESTHETICS, COMBINED; ANESTHETICS, LOCAL; CROSS-OVER STUDIES; FEMALE; HUMANS; INJECTIONS; LIDOCAINE; LIPOSOMES; MALE; MOUTH MUCOSA; NEEDLES; PAIN; PAIN MEASUREMENT; PALATE; PLACEBOS; PRILOCAINE; SEX FACTORS; SINGLE-BLIND METHOD; YOUNG ADULT;

EID: 84855277363     PISSN: 02664356     EISSN: 15321940     Source Type: Journal    
DOI: 10.1016/j.bjoms.2010.10.018     Document Type: Article

References (24)

1. J.G. Meechan Intra-oral topical anaesthetics: a review J Dent 28 2000 3 14
2. J.G. Meechan, P.C. Howlett, and B.D. Smith Factors influencing the discomfort of intraoral needle penetration Anesth Prog 52 2005 91 94
3. J.G. Meechan Effective topical anesthetic agents and techniques Dent Clin North Am 46 2002 759 766
4. B.F. McArdle Painless palatal anesthesia J Am Dent Assoc 128 1997 647
5. T. Harker What injection? Br Dent J 182 1997 50
6. P. Svensson, and J.K. Petersen Anesthetic effect of EMLA occluded with Orahesive oral bandages on oral mucosa. A placebo-controlled study Anesth Prog 39 1992 79 82 (Pubitemid 23173645)
7. C.J. Gill, and D.L. Orr II A double-blind crossover comparison of topical anesthetics J Am Dent Assoc 98 1979 213 214
8. B.J. Keller Comparison of the effectiveness of two topical anesthetics and a placebo in reducing injection pain Hawaii Dent J 16 1985 10 11
9. H.S. Hutchins Jr, F.A. Young, D.T. Lackland, and C.P. Fishburne The effectiveness of topical anesthesia and vibration in alleviating the pain of oral injections Anesth Prog 44 1997 87 89
10. H. Fukayama, N. Suzuki, and M. Umino Comparison of topical anesthesia of 20% benzocaine and 60% lidocaine gel Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94 2002 157 161 (Pubitemid 41124783)
11. A. Holst, and H. Evers Experimental studies of new topical anaesthetics on the oral mucosa Swed Dent J 9 1985 185 191
12. M.A. Al-Melh, and L. Andersson Comparison of topical anesthetics (EMLA/Oraqix vs. benzocaine) on pain experienced during palatal needle injection Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103 2007 e16 e20
13. M.A. Al-Melh, and L. Andersson Reducing pain from palatal needle stick by topical anesthetics: a comparative study between two lidocaine/prilocaine substances J Clin Dent 19 2008 43 47
14. J.G. Meechan, and R.A. Winter A comparison of topical anaesthesia and electronic nerve stimulation for reducing the pain of intra-oral injections Br Dent J 181 1996 333 335 (Pubitemid 126465464)
15. J.G. Meechan The use of EMLA for an intraoral soft-tissue biopsy in a needle phobic: a case report Anesth Prog 48 2001 32 34
16. A. Gesztes, and M. Mezei Topical anesthesia of the skin by liposome-encapsulated tetracaine Anesth Analg 67 1988 1079 1081 (Pubitemid 18260751)
17. M. Foldvari In vitro cutaneous and percutaneous delivery and in vivo efficacy of tetracaine from liposomal and conventional vehicles Pharm Res 11 1994 1593 1598 (Pubitemid 24339680)
18. B.D. Bucalo, E.J. Mirikitani, and R.L. Moy Comparison of skin anesthetic effect of liposomal lidocaine, nonliposomal lidocaine, and EMLA using 30-minute application time Dermatol Surg 24 1998 537 541 (Pubitemid 28225956)
19. R. Fisher, O. Hung, M. Mezei, and R. Stewart Topical anaesthesia of intact skin: liposome-encapsulated tetracaine vs EMLA Br J Anaesth 81 1998 972 973 (Pubitemid 28561338)
20. P.M. Friedman, J.P. Fogelman, K. Nouri, V.J. Levine, and R. Ashinoff Comparative study of the efficacy of four topical anesthetics Dermatol Surg 25 1999 950 954 (Pubitemid 30021617)
21. M. Franz-Montan, A.L. Silva, K. Cogo, C. Bergamaschi Cde, M.C. Volpato, and J. Ranali Liposome-encapsulated ropivacaine for topical anesthesia of human oral mucosa Anesth Analg 104 2007 1528 1533
22. D.R. de Araujo, C.M. Cereda, G.B. Brunetto, V.U. Vomero, A. Pierucci, and H.S. Neto Pharmacological and local toxicity studies of a liposomal formulation for the novel local anaesthetic ropivacaine J Pharm Pharmacol 60 2008 1449 1457
23. O.R. Hung, L. Comeau, M.R. Riley, S. Tan, S. Whynot, and M. Mezei Comparative topical anaesthesia of EMLA and liposome-encapsulated tetracaine Can J Anaesth 44 1997 707 711 (Pubitemid 27458673)
24. M. Franz-Montan, J. Ranali, J.C. Ramacciato, E.D. de Andrade, M.C. Volpato, and F.C. Groppo Ulceration of gingival mucosa after topical application of EMLA: report of four cases Br Dent J 204 2008 133 134