Effects of female sex hormones on clusterin expression and paclitaxel resistance in endometrial cancer cell lines

International Journal of Medical Sciences

Volumn 9, Issue 1, 2011, Pages 86-92

  Won, Yong Sung ^a   Lee, Sung Jong ^a   Yeo, Seung Geun ^b   Park, Dong Choon ^a  

^a The Catholic University of Korea   (South Korea)

^b Kyung Hee University   (South Korea)

Author keywords

Clusterin; Endometrial cancer; Estrogen; Paclitaxel; Progesterone

Indexed keywords

CLUSTERIN; CLUSTERIN RECEPTOR; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; PACLITAXEL; PROGESTERONE; PROGESTERONE RECEPTOR; PROGESTERONE RECEPTOR B; RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ESTRADIOL; PROGESTERONE RECEPTOR AB; SEX HORMONE;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DRUG RESISTANCE; ENDOMETRIUM CANCER; FEMALE; HUMAN; HUMAN CELL; IC 50; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANTINEOPLASTIC ACTIVITY; CANCER CELL CULTURE; CANCER RESISTANCE; CELL ASSAY; CELL SURVIVAL; CONCENTRATION RESPONSE; CORRELATIONAL STUDY; DRUG SENSITIVITY; HORMONE ACTION;

EID: 84855273848     PISSN: 14491907     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijms.9.86     Document Type: Article

References (35)

1. Ito K, Utsunomiya H, Yaegashi N, Sasano H. Biological roles of estrogen and progesterone in human endometrial carcino-ma--new developments in potential endocrine therapy for en-dometrial cancer. Endocr J. 2007;54:667-79.
2. Toffanin S, Daidone MG, Miodini P, De Cecco L, Gandellini P, Cappelletti V. Clusterin:a potential target for improving response to antiestrogens. Int J Oncol.2008; 33:791-8.
3. Blaschuk O, Burdzy K, Fritz IB. Purification and characterization of a cell-aggregating factor (clusterin), the major glycopro-tein in ram rete testis fluid. J Biol Chem. 1983;258:7714-20.
4. Jenne DE, Tschopp J. Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid. Proc Natl Acad Sci U S A. 1989;86:7123-7
5. Kirszbaum L, Sharpe JA, Murphy B, d'Apice AJ, Classon B, Hudson P, Walker ID. Molecular cloning and characterization of the novel, human complement-associated protein, SP-40,40: a link between the complement and reproductive systems. EMBO J. 1989;8:711-8.
6. de Silva HV, Harmony JA, Stuart WD, Gil CM, Robbins J. Apolipoprotein J: structure and tissue distribution. Biochemistry. 1990;29:5380-9.
7. Purrello M, Bettuzzi S, Di Pietro C, Mirabile E, Di Blasi M, Rimini R, Grzeschik KH, Ingletti C, Corti A, Sichel G. The gene for SP-40,40, human homolog of rat sulfated glycoprotein 2, rat clusterin, and rat testosterone-repressed prostate message 2, maps to chromosome 8. Genomics. 1991; 10:151-6.
8. O'Sullivan J, Whyte L, Drake J, Tenniswood M. Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis. Cell Death Differ. 2003;10:914-27.
9. Yang CR, Leskov K, Hosley-Eberlein K, Criswell T, Pink JJ, Kinsella TJ, Boothman DA. Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death. Proc Natl Acad Sci USA. 2000;97:5907-12.
10. Fritz IB, Burdzy K, Sétchell B, Blaschuk O. Ram rete testis fluid contains a protein (clusterin) which influences cell-cell interactions in vitro. Biol Reprod. 1983;28:1173-88.
11. Kirszbaum L, Sharpe JA, Murphy B, d'Apice AJ, Classon B, Hudson P, Walker ID. Molecular cloning and characterization of the novel, human complement-associated protein, SP-40,40: a link between the complement and reproductive systems. EMBOJ. 1989;8:711-8.
12. Parczyk K, Pilarsky C, Rachel U, Koch-Brandt C. Gp80 (clus-terin; TRPM-2) mRNA level is enhanced in human renal clear cell carcinomas. J Cancer Res Clin Oncol. 1994;120:186-8.
13. Hough CD, Cho KR, Zonderman AB, Schwartz DR, Morin PJ. Coordinately up-regulated genes in ovarian cancer. Cancer Res. 2001;61:3869-76.
14. Ouyang XS, Wang X, Lee DT, Tsao SW, Wong YC. Up-regulation of TRPM-2, MMP-7 and ID-1 during sex hormone-induced prostate carcinogenesis in the Noble rat. Car-cinogenesis. 2001;22:965-73.
15. Redondo M, Villar E, Torres-Muñoz J, Tellez T, Morell M, Petito CK. Overexpression of clusterin in human breast carcinoma. Am J Pathol. 2000;157:393-9.
16. Chi KN, Eisenhauer E, Fazli L, Jones EC, Goldenberg SL, Powers J, Tu D, Gleave ME. A phase I pharmacokinetic and phar-macodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer. J Natl Cancer Inst. 2005;97:1287-96.
17. Djeu JY, Wei S. Clusterin and chemoresistance. Adv Cancer Res. 2009;105:77-92.
18. Bettuzzi S. Chapter 1: Introduction. Adv Cancer Res. 2009;104:1-8.
19. Chen X, Halberg RB, Ehrhardt WM, Torrealba J, Dove WF. Clusterin as a biomarker in murine and human intestinal neo-plasia. Proc Natl Acad Sci U S A. 2003;100:9530-5.
20. Redondo M, Villar E, Torres-Muñoz J, Tellez T, Morell M, Petito CK. Overexpression of clusterin in human breast carcinoma. Am J Pathol. 2000;157:393-9
21. Xie D, Lau SH, Sham JS, Wu QL, Fang Y, Liang LZ, Che LH, Zeng YX, Guan XY. Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma. Cancer. 2005;103:277-83.
22. Lau SH, Sham JS, Xie D, Tzang CH, Tang D, Ma N, Hu L, Wang Y, Wen JM, Xiao G, Zhang WM, Lau GK, Yang M, Guan XY. Clusterin plays an important role in hepatocellular carcinoma metastasis. Oncogene. 2006;25:1242-50.
23. Saffer H, Wahed A, Rassidakis GZ, Medeiros LJ. Clusterin expression in malignant lymphomas: a survey of 266 cases. Mod Pathol. 2002;15:1221-6.
24. So A, Sinnemann S, Huntsman D, Fazli L, Gleave M. Knockdown of the cytoprotective chaperone, clusterin, chemosensi-tizes human breast cancer cells both in vitro and in vivo. Mol Cancer Ther. 2005;4:1837-49.
25. Miyake H, Nelson C, Rennie PS, Gleave ME. Acquisition of chemoresistant phenotype by overexpression of the antiapop-totic gene testosterone-repressed prostate message-2 in prostate cancer xenograft models. Cancer Res. 2000;60:2547-54.
26. Cervellera M, Raschella G, Santilli G, Tanno B, Ventura A, Mancini C, Sevignani C, Calabretta B, Sala A. Direct transacti-vation of the anti-apoptotic gene apolipoprotein J (clusterin) by B-MYB. J Biol Chem. 2000;275:21055-60.
27. Chung J, Kwak C, Jin RJ, Lee CH, Lee KH, Lee SE. Enhanced chemosensitivity of bladder cancer cells to cisplatin by suppression of clusterin in vitro. Cancer Lett. 2004;203:155-61.
28. Zellweger T, Miyake H, July LV, Akbari M, Kiyama S, Gleave ME. Chemosensitization of human renal cell cancer using anti-sense oligonucleotides targeting the antiapoptotic gene clus-terin. Neoplasia. 2001;3:360-7.
29. Ahn HJ, Bae J, Lee S, Ko JE, Yoon S, Kim SJ, Sakuragi N. Differential expression of clusterin according to histological type of endometrial carcinoma. Gynecol Oncol. 2008;110:222-9.
30. Ranney MK, Ahmed IS, Potts KR, Craven RJ. Multiple pathways regulating the anti-apoptotic protein clusterin in breast cancer. Biochim Biophys Acta. 2007;1772:1103-11.
31. Flanagan L, Whyte L, Chatterjee N, Tenniswood M. Effects of clusterin over-expression on metastatic progression and therapy in breast cancer. BMC Cancer. 2010;10:107.
32. Leskov KS, Klokov DY, Li J, Kinsella TJ, Boothman DA. Synthesis and functional analysis of nuclear clusterin:a cell death protein. J Biol Chem 2003;278:11590 - 600.
33. Rizzi F, Bettuzzi S. The clusterin paradigm in prostate and breast carcinogenesis. Endocr Relat Cancer. 2010; 17:R1-17.
34. Kim JJ, Chapman-Davis E. Role of progesterone in endometrial cancer. Semin Reprod Med. 2010; 28:81-90.
35. Lange CA, Yee D. Progesterone and breast cancer. Womens Health (Lond Engl). 2008;4:151-62.