Persistence of mortality risk in patients with acute cardiac diseases and mild thyroid dysfunction

American Journal of the Medical Sciences

Volumn 343, Issue 1, 2012, Pages 65-70

  Molinaro, Sabrina ^a   Iervasi, Giorgio ^a   Lorenzoni, Valentina ^a   Coceani, Michele ^c   Landi, Patrizia ^a   Srebot, Vera ^a   Mariani, Fabio ^a   L'Abbate, Antonio ^b   Pingitore, Alessandro ^a  

^a INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^b SCUOLA SUPERIORE SANT ANNA   (Italy)

^c Institue of Applied Physics Nello Carrara   (Italy)

Author keywords

Acute cardiac diseases; Low T3 syndrome; Prognosis; Subclinical hyperthyroidism; Subclinical hypothyroidism

Indexed keywords

C REACTIVE PROTEIN; CREATININE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIOTHYRONINE; THYROID HORMONE; THYROTROPIN;

ACUTE HEART FAILURE; ACUTE HEART INFARCTION; ADULT; AGED; AORTA STENOSIS; AORTA VALVE REGURGITATION; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENDOCARDITIS; EUTHYROIDISM; FEMALE; FOLLOW UP; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; HEART ATRIUM ARRHYTHMIA; HEART DEATH; HEART TAMPONADE; HEART VENTRICLE ARRHYTHMIA; HUMAN; HYPOTHYROIDISM; LIOTHYRONINE BLOOD LEVEL; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MYOCARDITIS; PERICARDITIS; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SYNCOPE; THYROID DISEASE; UNSTABLE ANGINA PECTORIS;

EID: 84855267025     PISSN: 00029629     EISSN: 15382990     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e31822846bd     Document Type: Article

References (29)

1. Biondi B, Fazio S, Palmieri EA, et al. Left ventricular diastolic dysfunction in patients with subclinical hypothyroidism. J Clin Endocrinol Metab 1999;84:2064-7. (Pubitemid 30647034)
2. Biondi B, Palmieri EA, Lombardi G, et al. Effects of subclinical thyroid dysfunction on the heart. Ann Intern Med 2002;137:904-14. (Pubitemid 35416626)
3. Bielecka-Dabrowa A, Mikhailidis DP, Rysz J, et al. The mechanisms of atrial fibrillation in hyperthyroidism. Thyroid Res 2009;22:4.
4. Biondi B, Galderisi M, Pagano L, et al. Endothelial-mediated coronary flow reserve in patients with mild thyroid hormone deficiency. Eur J Endocrinol 2009;161:323-9.
5. Akcakoyun M, Kaya H, Kargin R, et al. Abnormal left ventricular longitudinal functional reserve assessed by exercise pulsed wave tissue Doppler imaging in patients with subclinical hypothyroidism. J Clin Endocrinol Metab 2009;94:2979-83.
6. Smit JW, Eustatia-Rutten CF, Corssmit EP, et al. Reversible diastolic dysfunction after long-term exogenous subclinical hyperthyroidism: a randomized, placebo-controlled study. J Clin Endocrinol Metab 2005;90:6041-7. (Pubitemid 41606523)
7. Ripoli A, Pingitore A, Favilli B, et al. Does subclinical hypothyroidism affect cardiac pump performance? Evidence from a magnetic resonance imaging study. J Am Coll Cardiol 2005;45:439-45. (Pubitemid 40186797)
8. Hak AE, Pols HAP, Visser TJ, et al. Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam Study. Ann Intern Med 2000;132:70-8.
9. Cappola AR, Fried LP, Arnold AM, et al. Thyroid status, cardiovascular risk, and mortality in older adults. JAMA 2006;295:1033-41.
10. Parle JV, Maisonneuve P, Sheppard MC, et al. Prediction of allcause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study. Lancet 2001;358:861-5. (Pubitemid 32900566)
11. Ochs N, Auer R, Bauer DC, et al. Meta-analysis: subclinical thyroid dysfunction and the risk for coronary heart disease and mortality. Ann Intern Med 148:832-1845.
12. De Groot LJ. Dangerous dogmas in medicine: the nonthyroidal illness syndrome. (1999). J Clin Endocrin Metab 2008;84:151-64.
13. Chen YF, Redetzke RA, Said S, et al. Changes in left ventricular function and remodeling after myocardial infarction in hypothyroid rats. Am J Physiol Heart Circ Physiol 2010;298:H259-H262.
14. Tang YD, Kuzman JA, Said S, et al. Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunction. Circulation 2005;112:3122-30. (Pubitemid 43113443)
15. Pantos C, Mourouzis I, Cokkinos DV. New insights into the role of thyroid hormone in cardiac remodelling: time to reconsider? Heart Fail Rev 2011;16:79-96.
16. Iervasi G, Pingitore A, Landi P, et al. Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease. Circulation 2003;107:708-13. (Pubitemid 36222598)
17. Pingitore A, Landi P, Taddei MC, et al. T3 levels for risk stratification of patients with chronic heart failure. Am J Med 2005;118:132-6. (Pubitemid 40202859)
18. Iervasi G, Molinaro S, Landi P, et al. Association between increased mortality and mild thyroid dysfunction in cardiac patients. Arch Intern Med 2007;167:1526-32. (Pubitemid 47124183)
19. Rodondi N, den Elzen WP, Bauer DC, et al. Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA 2010;304:1365-74.
20. Freiberg L, Drvota V, Bjelak AH, et al. Association between increased levels of reverse T3 and mortality after acute myocardial infarction. Am J Med 2001;111:699-703. (Pubitemid 34017521)
21. Surks MI, Ortiz E, Daniles GH, et al. Subclinical thyroid disease. Scientific review and guidelines for diagnosis and management. JAMA 2004;291:228-38. (Pubitemid 38082818)
22. Hamilton MA, Stevenson LW, Luu M, et al. Altered thyroid hormone metabolism in advanced heart failure. J Am Coll Cardiol 1990;16:91-5. (Pubitemid 20217047)
23. Opasich C, Pacini F, Ambrosino N, et al. Sick euthyroid syndrome in patients with moderate-to-severe chronic heart failure. Eur Heart J 1996;17:1860-6. (Pubitemid 26413920)
24. Kozdag G, Ural D, Vural A, et al. Relation between free triiodothyronine/free thyroxine ratio, echocardiographic parameters and mortality in dilated cardiomyopathy. Eur J Heart Fail 2005;7:113-8. (Pubitemid 40092502)
25. Kvetny J, Heldgaard PE, Bladbjerg EM, et al. Subclinical hypothyroidism is associated with a low-grade inflammation, increased triglyceride levels and predicts cardiovascular disease in males below 50 years. Clin Endocrinol 2004;61:232-8. (Pubitemid 39093119)
26. Iamizumi M, Akahoshi M, Ichimaru S, et al. Risk for ischemic heart disease and all-cause mortality in subclinical hypothyroidism. J Clin Endocrinol Metab 2004;89:3365-70. (Pubitemid 38951905)
27. Baajafer FS, Hammami MM, Mohamed GE. Prevalence and severity of hyponatremia and hypercreatininemia in short-term uncomplicated hypothyroidism. J Endocrinol Invest 1999;22:35-9. (Pubitemid 29095012)
28. Rodondi N, Newman AB, Vittinghoff E, et al. Subclinical hypothyroidism and the risk of heart failure, other cardiovascular events, and death. Arch Intern Med 2005;165:2460-6. (Pubitemid 41720006)
29. Walsh JP, Bremner AP, Bulsara MK, et al. Subclinical thyroid dysfunction as a risk factor for cardiovascular disease. Arch Intern Med 2005;165:2467-72. (Pubitemid 41720007)