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Volumn 3, Issue 1, 2012, Pages 135-140

Sensitization of breast cancer cells to taxol by inhibition of taxol resistance gene 1

Author keywords

Breast cancer; Multidrug resistance; Taxol resistance; Taxol resistance gene 1; Thrombospondin 1

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; GLUTATHIONE TRANSFERASE P1; PACLITAXEL; PROTEIN; SMALL INTERFERING RNA; TAXOL RESISTANCE PROTEIN 1; THROMBOSPONDIN 1; UNCLASSIFIED DRUG;

EID: 84855244929     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2011.416     Document Type: Article
Times cited : (15)

References (22)
  • 1
    • 33846781391 scopus 로고    scopus 로고
    • Pharmacogenetics and oncology treatment for breast cancer
    • Marsh S and McLeod HL: Pharmacogenetics and oncology treatment for breast cancer. Expert Opin Pharmacother 8: 119-127, 2007.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 119-127
    • Marsh, S.1    McLeod, H.L.2
  • 2
    • 35248830049 scopus 로고    scopus 로고
    • Breast-cancer therapy-looking back to the future
    • Moore A: Breast-cancer therapy-looking back to the future. N Engl J Med 357: 1547-1549, 2007.
    • (2007) N Engl J Med , vol.357 , pp. 1547-1549
    • Moore, A.1
  • 3
    • 0026516994 scopus 로고
    • Mechanism of action of taxol
    • Horwitz SB: Mechanism of action of taxol. Trends Pharmacol Sci 13: 134-136, 1992.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 134-136
    • Horwitz, S.B.1
  • 5
    • 70349826431 scopus 로고    scopus 로고
    • Understanding the causes of multidrug resistance in cancer: A comparison of doxorubicin and sunitinib
    • Broxterman HJ, Gotink KJ and Verheul HM: Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib. Drug Resist Updat 12: 114-126, 2009.
    • (2009) Drug Resist Updat , vol.12 , pp. 114-126
    • Broxterman, H.J.1    Gotink, K.J.2    Verheul, H.M.3
  • 7
    • 0037444386 scopus 로고    scopus 로고
    • Elevated levels of microtubule destabilizing factors in a taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation
    • Martello LA, Verdier-Pinard P, Shen HJ, He L, Torres K, Orr GA and Horwitz SB: Elevated levels of microtubule destabilizing factors in a taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation. Cancer Res 63: 1207-1213, 2003.
    • (2003) Cancer Res , vol.63 , pp. 1207-1213
    • Martello, L.A.1    Verdier-Pinard, P.2    Shen, H.J.3    He, L.4    Torres, K.5    Orr, G.A.6    Horwitz, S.B.7
  • 8
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T and Bates SE: Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2: 48-58, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 10
    • 54249093808 scopus 로고    scopus 로고
    • Alteration of the mitochondrial apoptotic pathway is key to acquired paclitaxel resistance and can be reversed by ABT-737
    • Kutuk O and Letai A: Alteration of the mitochondrial apoptotic pathway is key to acquired paclitaxel resistance and can be reversed by ABT-737. Cancer Res 68: 7985-7994, 2008.
    • (2008) Cancer Res , vol.68 , pp. 7985-7994
    • Kutuk, O.1    Letai, A.2
  • 11
    • 44949129002 scopus 로고    scopus 로고
    • The taxane limbo: How low can we go?
    • Hudis C and Dang C: The taxane limbo: how low can we go? J Natl Cancer Inst 100: 761-763, 2008.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 761-763
    • Hudis, C.1    Dang, C.2
  • 12
    • 33746542655 scopus 로고    scopus 로고
    • Txr1: A transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes
    • Lih CJ, Wei W and Cohen SN: Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes. Genes Dev 20: 2082-2095, 2006.
    • (2006) Genes Dev , vol.20 , pp. 2082-2095
    • Lih, C.J.1    Wei, W.2    Cohen, S.N.3
  • 13
    • 0343091300 scopus 로고    scopus 로고
    • Thrombospondin-1 induces endothelial cell apoptosis and inhibits angiogenesis by activating the caspase death pathway
    • Nor JE, Mitra RS, Sutorik MM, Mooney DJ, Castle VP and Polverini PJ: Thrombospondin-1 induces endothelial cell apoptosis and inhibits angiogenesis by activating the caspase death pathway. J Vasc Res 37: 209-218, 2000.
    • (2000) J Vasc Res , vol.37 , pp. 209-218
    • Nor, J.E.1    Mitra, R.S.2    Sutorik, M.M.3    Mooney, D.J.4    Castle, V.P.5    Polverini, P.J.6
  • 15
    • 0013682470 scopus 로고
    • Distinct P-glycoprotein precursors are overproduced in independently isolated drug-resistant cell lines
    • Greenberger LM, Lothstein L, Williams SS and Horwitz SB: Distinct P-glycoprotein precursors are overproduced in independently isolated drug-resistant cell lines. Proc Natl Acad Sci USA 85: 3762-3766, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 3762-3766
    • Greenberger, L.M.1    Lothstein, L.2    Williams, S.S.3    Horwitz, S.B.4
  • 16
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan MA and Wilson L: Microtubules as a target for anticancer drugs. Nat Rev Cancer 4: 253-265, 2004.
    • (2004) Nat Rev Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 17
    • 33746598247 scopus 로고    scopus 로고
    • TXR1-mediated thrombo-spondin repression: A novel mechanism of resistance to taxanes?
    • Van Amerongen R and Berns A: TXR1-mediated thrombo-spondin repression: a novel mechanism of resistance to taxanes? Genes Dev 20: 1975-1981, 2006.
    • (2006) Genes Dev , vol.20 , pp. 1975-1981
    • van Amerongen, R.1    Berns, A.2
  • 18
    • 0345688612 scopus 로고    scopus 로고
    • Mechanisms of taxol resistance related to microtubules
    • Orr GA, Verdier-Pinard P, McDaid H and Horwitz SB: Mechanisms of taxol resistance related to microtubules. Oncogene 22: 7280-7295, 2003.
    • (2003) Oncogene , vol.22 , pp. 7280-7295
    • Orr, G.A.1    Verdier-Pinard, P.2    McDaid, H.3    Horwitz, S.B.4
  • 19
    • 0031974895 scopus 로고    scopus 로고
    • Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes
    • Ark-Otte J, Samelis G, Rubio G, Lopez Saez JB, Pinedo HM and Giaccone G: Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes. Oncol Rep 5: 249-255, 1998.
    • (1998) Oncol Rep , vol.5 , pp. 249-255
    • Ark-Otte, J.1    Samelis, G.2    Rubio, G.3    Lopez, S.J.B.4    Pinedo, H.M.5    Giaccone, G.6
  • 21
    • 0031019309 scopus 로고    scopus 로고
    • Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells
    • Lavie Y, Cao H, Volner A, Lucci A, Han TY, Geffen V, Giuliano AE and Cabot MC: Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells. J Biol Chem 272: 1682-1687, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 1682-1687
    • Lavie, Y.1    Cao, H.2    Volner, A.3    Lucci, A.4    Han, T.Y.5    Geffen, V.6    Giuliano, A.E.7    Cabot, M.C.8
  • 22
    • 13644254794 scopus 로고    scopus 로고
    • Molecular mechanisms of drug resistance
    • Longley D and Johnston P: Molecular mechanisms of drug resistance. J Pathol 205: 275-292, 2005.
    • (2005) J Pathol , vol.205 , pp. 275-292
    • Longley, D.1    Johnston, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.