High-dose intravenous immunoglobulin monotherapy for drug-induced hypersensitivity syndrome

Acta Dermato-Venereologica

Volumn 92, Issue 1, 2012, Pages 100-101

  Kito, Yukiko ^a   Ito, Taisuke ^a   Tokura, Yoshiki ^a   Hashizume, Hideo ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIBIOTIC AGENT; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; HUMAN HERPESVIRUS 6 ANTIBODY; HUMAN HERPESVIRUS 6 IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; MEXILETINE; UNCLASSIFIED DRUG; VIRUS ANTIBODY;

ADULT; ANTIBIOTIC THERAPY; BACTERIUM CULTURE; CASE REPORT; CERVICAL LYMPHADENOPATHY; CHONDROSARCOMA; DRUG HYPERSENSITIVITY; DRUG MEGADOSE; EOSINOPHILIA; FACE EDEMA; FEMALE; FEVER; HUMAN; HUMAN HERPESVIRUS 6; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; INGUINAL LYMPHADENOPATHY; KLEBSIELLA PNEUMONIAE INFECTION; LETTER; LEUKOCYTE COUNT; LYMPHADENOPATHY; LYMPHOCYTE TRANSFORMATION TEST; LYMPHOCYTIC INFILTRATION; MACULOPAPULAR RASH; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MONOTHERAPY; NERVE INJURY; NEUROPATHIC PAIN; PATCH TEST; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; SERRATIA INFECTION; SURGICAL INFECTION;

ANTIBODIES, VIRAL; DRUG HYPERSENSITIVITY; FEMALE; HERPESVIRUS 6, HUMAN; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; MEXILETINE; MIDDLE AGED;

EID: 84855243971     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: 10.2340/00015555-1168     Document Type: Letter

References (12)

1. Hashimoto K, Yasukawa M, Tohyama M. Human herpesvirus 6 and drug allergy. Curr Opin Allergy Clin Immunol 2003; 3: 255-260.
2. Kardaun SH, Sidoroff A, Valeyrie-Allanore L, Halevy S, Davidovici BB, Mockenhaupt M, et al. Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist? Br J Dermatol 2007; 156: 609-611.
3. Shiohara T, Iijima M, Ikezawa Z, Hashimoto K. The diagnosis of a DRESS syndrome has been sufficiently established on the basis of typical clinical features and viral reactivations. Br J Dermatol 2007; 156: 1083-1084.
4. Tohyama M, Hashimoto K, Yasukawa M, Kimura H, Horikawa T, Nakajima K, et al. Association of human herpesvirus 6 reactivation with the flaring and severity of drug-induced hypersensitivity syndrome. Br J Dermatol 2007; 157: 934-940.
5. Tas S, Simonart T. Management of drug rash with eosinophilia and systemic symptoms (DRESS syndrome): an update. Dermatology 2003; 206: 353-356.
6. Fields KS, Petersen MJ, Chiao E, Tristani-Firouzi P. Case reports: treatment of nevirapine-associated dress syndrome with intravenous immune globulin (IVIG). J Drugs Dermatol 2005; 4: 510-513.
7. Santos RP, Ramilo O, Barton T. Nevirapine-associated rash with eosinophilia and systemic symptoms in a child with human immunodeficiency virus infection. Pediatr Infect Dis J 2007; 26: 1053-1056.
8. Hashizume H, Takigawa M. Drug-induced hypersensitivity syndrome associated with cytomegalovirus reactivation: immunological characterization of pathogenic T cells. Acta Derm Venereol 2005; 85: 47-50.
9. Takahashi R, Kano Y, Yamazaki Y, Kimishima M, Mizukawa Y, Shiohara T. Defective regulatory T cells in patients with severe drug eruptions: timing of the dysfunction is associated with the pathological phenotype and outcome. J Immunol 2009; 182: 8071-8079.
10. Kano Y, Inaoka M, Shiohara T. Association between anticonvulsant hypersensitivity syndrome and human herpesvirus 6 reactivation and hypogammaglobulinemia. Arch Dermatol 2004; 140: 183-188.
11. Kano Y, Inaoka M, Sakuma K, Shiohara T. Virus reactivation and intravenous immunoglobulin (IVIG) therapy of drug-induced hypersensitivity syndrome. Toxicology 2005; 209: 165-167.
12. Orange JS, Hossny EM, Weiler CR, Ballow M, Berger M, Bonilla FA, et al. Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology. J Allergy Clin Immunol 2006; 117: S525-553.