Interplay between depressive-like behavior and the immune system in an animal model of prenatal dexamethasone administration

Frontiers in Behavioral Neuroscience

Volumn , Issue FEBRUARY, 2011, Pages

  Roque, Susana ^a   Oliveira, Tiago Gil ^a   Nobrega, Claudia ^a   Barreira Silva, Palmira ^a   Nunes Alves, Cláudio ^a   Sousa, Nuno ^a   Palha, Joana Almeida ^a   Correia Neves, Margarida ^a  

^a UNIVERSITY OF MINHO   (Portugal)

Author keywords

Behavior; Depression; Dexamethasone; Immunity; Listeria monocytogenes; Prenatal

Indexed keywords

DEXAMETHASONE; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BACTERIAL IMMUNITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL STIMULATION; CONTROLLED STUDY; DEPRESSION; FEMALE; IMMUNE SYSTEM; IN VITRO STUDY; INFLAMMATION; LISTERIA MONOCYTOGENES; LISTERIOSIS; MALE; MARE; NONHUMAN; PRENATAL DRUG EXPOSURE; PROTEIN BLOOD LEVEL; RAT; REGULATORY T LYMPHOCYTE; SPLEEN CELL;

EID: 84855237730     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnbeh.2011.00004     Document Type: Article

References (34)

1. Ashwell, J. D., Lu, F. W., and Vacchio, M. S. (2000). Glucocorticoids in T cell development and function. Annu. Rev. Immunol. 18, 309-345.
2. Bakker, J. M., Kavelaars, A., Kamphuis, P. J., Cobelens, P. M., van Vugt, H. H., van Bel, F., and Heijnen, C. J. (2000). Neonatal dexamethasone treatment increases susceptibility to experimental autoimmune disease in adult rats. J. Immunol. 165, 5932-5937.
3. Bakker, J. M., Kavelaars, A., Kamphuis, P. J., Zijlstra, J., van Bel, F., and Heijnen, C. J. (2001). Neonatal dexamethasone treatment induces long-lasting changes in T-cell receptor vbeta repertoire in rats. J. Neuroimmunol. 112, 47-54
4. Bakker, J. M., Schmidt, E. D., Kroes, H., Kavelaars, A., Heijnen, C. J., Tilders, F. J., and van Rees, E. P. (1995). Effects of short-term dexamethasone treatment during pregnancy on the development of the immune system and the hypothalamo-pituitary adrenal axis in the rat. J. Neuroimmunol. 63, 183-191
5. Barber, A. E., Coyle, S. M., Marano, M. A., Fischer, E., Calvano, S. E., Fong, Y., Moldawer, L. L., and Lowry, S. F. (1993). Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man. J. Immunol. 150, 1999-2006.
6. Bessa, J. M., Ferreira, D., Melo, I., Marques, F., Cerqueira, J. J., Palha, J. A., Almeida, O. F., and Sousa, N. (2009). The moodimproving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling. Mol. Psychiatry 14, 764-773, 739.
7. Cabanes, D., Lecuit, M., and Cossart, P. (2008). Animal models of Listeria infection. Curr. Protoc. Microbiol. Chapter 9, Unit9B.1
8. Coe, C. L., and Lubach, G. R. (2000). Prenatal influences on neuroimmune set points in infancy. Ann. N. Y. Acad. Sci. 917, 468-477.
9. Coe, C. L., and Lubach, G. R. (2005). Developmental consequences of antenatal dexamethasone treatment in nonhuman primates. Neurosci. Biobehav. Rev. 29, 227-235.
10. Dietert, R. R., Lee, J. E., Olsen, J., Fitch, K., and Marsh, J. A. (2003). Developmental immunotoxicity of dexamethasone: comparison of fetal versus adult exposures. Toxicology 194, 163-176.
11. Galon, J., Franchimont, D., Hiroi, N., Frey, G., Boettner, A., Ehrhart-Bornstein, M., O'Shea, J. J., Chrousos, G. P., and Bornstein, S. R. (2002). Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells. FASEB J. 16, 61-71
12. Goettsch, W., Garssen, J., de Klerk, A., Herremans, T. M., Dortant, P., de Gruijl, F. R., and Van Loveren, H. (1996). Effects of ultraviolet-B exposure on the resistance to Listeria monocytogenes in the rat. Photochem. Photobiol. 63, 672-679.
13. Goncalves, L., Silva, R., Pinto-Ribeiro, F., Pego, J. M., Bessa, J. M., Pertovaara, A., Sousa, N., and Almeida, A. (2008). Neuropathic pain is associated with depressive behaviour and induces neuroplasticity in the amygdala opf the rat. Exp. Neurol. 213, 48-56.
14. Hauser, J., Feldon, J., and Pryce, C. R. (2009). Direct and dam-mediated effects of prenatal dexamethasone on emotionality, cognition and HPA axis in adult Wistar rats. Horm. Behav. 56, 364-375.
15. Hirvikoski, T., Nordenstrom, A., Lindholm, T., Lindblad, F., Ritzen, E. M., Wedell, A., and Lajic, S. (2007). Cognitive functions in children at risk for congenital adrenal hyperplasia treated prenatally with dexamethasone. J. Clin. Endocrinol. Metab. 92, 542-548.
16. Hofmeyr, G. J. (2009). Antenatal Corticosteroids for Women at Risk of Preterm Birth: RHL Commentary. Geneva: The WHO Reproductive Health Library, World Health Organization
17. Holladay, S. D., and Smialowicz, R. J. (2000). Development of the murine and human immune system: differential effects of immunotoxicants depend on time of exposure. Environ. Health Perspect. 108(Suppl. 3), 463-473.
18. Karagiannidis, C., Akdis, M., Holopainen, P., Woolley, N. J., Hense, G., Ruckert, B., Mantel, P. Y., Menz, G., Akdis, C. A., Blaser, K., and Schmidt-Weber, C. B. (2004). Glucocorticoids upregulate Foxp3 expression and regulatory T cells in asthma. J. Allergy Clin. Immunol. 114, 1425-1433.
19. Karemaker, R., Kavelaars, A., ter Wolbeek, M., Tersteeg-Kamperman, M., Baerts, W., Veen, S., Samsom, J. F., Visser, G. H., van Bel, F., and Heijnen, C. J. (2008). Neonatal dexamethasone treatment for chronic lung disease of prematurity alters the hypothalamuspituitary-adrenal axis and immune system activity at school age. Pediatrics 121, e870-e878.
20. Leao, P., Sousa, J. C., Oliveira, M., Silva, R., Almeida, O. F., and Sousa, N. (2007). Programming effects of antenatal dexamethasone in the developing mesolimbic pathways. Synapse 61, 40-49
21. Mesquita, A. R., Correia-Neves, M., Roque, S., Castro, A. G., Vieira, P., Pedrosa, J., Palha, J. A., and Sousa, N. (2008). Il-10 modulates depressive-like behavior. J. Psychiatr. Res. 43, 89-97.
22. Mesquita, A. R., Wegerich, Y., Patchev, A. V., Oliveira, M., Leao, P., Sousa, N., and Almeida, O. F. (2009). Glucocorticoids and neuroand behavioural development. Semin. Fetal Neonatal Med. 14, 130-135.
23. Miller, A. H. (2010). Depression and immunity: a role for T cells? Brain Behav. Immun. 24, 1-8.
24. Miller, A. H., Maletic, V., and Raison, C. L. (2009). Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol. Psychiatry 65, 732-741.
25. Oliveira, M., Bessa, J. M., Mesquita, A., Tavares, H., Carvalho, A., Silva, R., Pego, J. M., Cerqueira, J. J., Palha, J. A., Almeida, O. F., and Sousa, N. (2006). Induction of a hyperanxious state by antenatal dexamethasone: a case for less detrimental natural corticosteroids. Biol. Psychiatry 59, 844-852.
26. Oliveira, M., Leão, P., Rodrigues, A.-J., Pêgo, J.-M., Cerqueira, J.-J., and Sousa, N. (2010). Programming effects of antenatal corticosteroids exposure in male sexual behavior. J. Sex. Med. doi:10.1111/j.1743-6109.2010.02170.x. [Epub ahead of print].
27. Pamer, E. G. (2004). Immune responses to Listeria monocytogenes. Nat. Rev. Immunol. 4, 812-823.
28. Rodrigues, A.-J., Leão, P., Oliveira, M., Pêgo, J.-M., Franky, A., Morgado, P., Mesquita, A., Araujo, D., Almeida, O. F., and Sousa, N. (2010). "Vulnerability to addiction can be modulated by dopamine," in Poster Presented at Society for Neurosciences, November 13-17
29. San Diego. Rook, G. A, and Lowry, C. A. (2008). The hygiene hypothesis and psychiatric disorders. Trends Immunol. 29, 150-158.
30. Roque, S., Correia-Neves, M., Mesquita, A. R., Palha, J. A., and Sousa, N. (2009). Interleukin-10: a key cytokine in depression? Cardiovasc. Psychiatry Neurol. 2009, 187894.
31. Sultzer, B. M., and Goodman, G. W. (1976). Endotoxin protein: a B-cell mitogen and polyclonal activator of C3h/Hej lymphocytes. J. Exp. Med. 144, 821-827.
32. Trautman, P. D., Meyer-Bahlburg, H. F., Postelnek, J., and New, M. I. (1995). Effects of early prenatal dexamethasone on the cognitive and behavioral development of young children: results of a pilot study. Psychoneuroendocrinology 20, 439-449.
33. Welberg, L. A., and Seckl, J. R. (2001). Prenatal stress, glucocorticoids and the programming of the brain. J. Neuroendocrinol. 13, 113-128.
34. Zhang, T. Y., and Daynes, R. A. (2007). Glucocorticoid conditioning of myeloid progenitors enhances Tlr4 signaling via negative regulation of the phosphatidylinositol 3-kinaseAkt pathway. J. Immunol. 178, 2517-2526.