Clinical characteristics and risk factors for mortality in patients with bacteremia caused by Pseudomonas aeruginosa

Internal Medicine

Volumn 51, Issue 1, 2012, Pages 59-64

  Horino, Tetsuya ^a   Chiba, Akio ^a   Kawano, Shinji ^a   Kato, Tetsuro ^a   Sato, Fumiya ^a   Maruyama, Yukio ^a   Nakazawa, Yasushi ^a   Yoshikawa, Koji ^a   Yoshida, Masaki ^a   Hori, Seiji ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bloodstream infections; Poor prognostic factors; Pseudomonas aeruginosa

Indexed keywords

AMINOGLYSIDE; CARBAPENEM; CEPHALOSPORIN; FLUOROQUINOLONE; IMMUNOSUPPRESSIVE AGENT; MONOBACTAM; PENICILLIN G; STEROID; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL THERAPY; ARTICLE; BACTEREMIA; BACTERIUM IDENTIFICATION; BLOODSTREAM INFECTION; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HEMATOLOGIC DISEASE; HUMAN; LEUKEMIA; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEUTROPENIA; POLYMICROBIAL BACTEREMIA; PROGNOSIS; PSEUDOMONAS AERUGINOSA; RETROSPECTIVE STUDY; RISK FACTOR; SOLID TUMOR; THROMBOCYTOPENIA;

AGED; ANTI-BACTERIAL AGENTS; BACTEREMIA; COHORT STUDIES; FEMALE; HUMANS; JAPAN; LEUKEMIA; LOGISTIC MODELS; MALE; MIDDLE AGED; PROGNOSIS; PSEUDOMONAS INFECTIONS; RETROSPECTIVE STUDIES; RISK FACTORS; THROMBOCYTOPENIA; URINARY TRACT INFECTIONS;

EID: 84855224466     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.51.5698     Document Type: Article

References (24)

1. Munoz P, Cruz AF, Rodriguez-Creixems M, Bouza E. Gramnegative bloodstream infections. Int J Antimicrob Agents 32(Suppl 1): S10-S14, 2008.
2. Kang CI, Kim SH, Kim HB, et al. Pseudomonas aeruginosa bacteremia: risk factors for mortality and influence of delayed receipt of effective antimicrobial therapy on clinical outcome. Clin Infect Dis 37: 745-751, 2003.
3. Bisbe J, Gatell JM, Puig J, et al. Pseudomonas aeruginosa bacteremia: univariate and multivariate analyses of factors influencing the prognosis in 133 episodes. Rev Infect Dis 10: 629-635, 1988.
4. Vidal F, Mensa J, Almela M, et al. Epidemiology and outcome of Pseudomonas aeruginosa bacteremia, with special emphasis on the influence of antibiotic treatment. Analysis of 189 episodes. Arch Intern Med 156: 2121-2126, 1996.
5. Maschmeyer G, Braveny I. Review of the incidence and prognosis of Pseudomonas aeruginosa infections in cancer patients in the 1990s. Eur J Clin Microbiol Infect Dis 19: 915-925, 2000.
6. Micek ST, Lloyd AE, Ritchie DJ, Reichley RM, Fraser VJ, Kollef MH. Pseudomonas aeruginosa bloodstream infection: importance of appropriate initial antimicrobial treatment. Antimicrob Agents Chemother 49: 1306-1311, 2005.
7. Vanderschueren S, De Weerdt A, Malbrain M, et al. Thrombocytopenia and prognosis in intensive care. Crit Care Med 28: 1871-1876, 2000.
8. Elting LS, Rubenstein EB, Rolston KV, Bodey GP. Outcomes of bacteremia in patients with cancer and neutropenia: observations from two decades of epidemiological and clinical trials. Clin Infect Dis 25: 247-259, 1997.
9. Aliaga L, Mediavilla JD, Llosa J, Miranda C, Rosa-Fraile M. Clinical significance of polymicrobial versus monomicrobial bacteremia involving Pseudomonas aeruginosa. Eur J Clin Microbiol Infect Dis 19: 871-874, 2000.
10. Zaragoza R, Artero A, Camarena JJ, Sancho S, Gonzalez R, Nogueira JM. The influence of inadequate empirical antimicrobial treatment on patients with bloodstream infections in an intensive care unit. Clin Microbiol Infect 9: 412-418, 2003.
11. Lodise TP Jr, Patel N, Kwa A, et al. Predictors of 30-day mortality among patients with Pseudomonas aeruginosa bloodstream infections: impact of delayed appropriate antibiotic selection. Antimicrob Agents Chemother 51: 3510-3515, 2007.
12. Tam VH, Rogers CA, Chang KT, Weston JS, Caeiro JP, Garey KW. Impact of multidrug-resistant Pseudomonas aeruginosa bacteremia on patient outcomes. Antimicrob Agents Chemother 54: 3717-3722, 2010.
13. Stephan F, Hollande J, Richard O, Cheffi A, Maier-Redelsperger M, Flahault A. Thrombocytopenia in a surgical ICU. Chest 115: 1363-1370, 1999.
14. Sharma B, Sharma M, Majumder M, Steier W, Sangal A, Kalawar M. Thrombocytopenia in septic shock patients-a prospective observational study of incidence, risk factors and correlation with clinical outcome. Anaesth Intensive Care 35: 874-880, 2007.
15. Baughman RP, Lower EE, Flessa HC, Tollerud DJ. Thrombocytopenia in the intensive care unit. Chest 104: 1243-1247, 1993.
16. Lai CH, Chi CY, Chen HP, et al. Clinical characteristics and prognostic factors of patients with Stenotrophomonas maltophilia bacteremia. J Microbiol Immunol Infect 37: 350-358, 2004.
17. Cisneros JM, Reyes MJ, Pachon J, et al. Bacteremia due to Acinetobacter baumannii: epidemiology, clinical findings, and prognostic features. Clin Infect Dis 22: 1026-1032, 1996.
18. Gikas A, Samonis G, Christidou A, et al. Gram-negative bacteremia in non-neutropenic patients: a 3-year review. Infection 26: 155-159, 1998.
19. Pittet D, Li N, Wenzel RP. Association of secondary and polymicrobial nosocomial bloodstream infections with higher mortality. Eur J Clin Microbiol Infect Dis 12: 813-819, 1993.
20. Lee IK, Liu JW. Clinical characteristics and risk factors for mortality in Morganella morganii bacteremia. J Microbiol Immunol Infect 39: 328-334, 2006.
21. Marra AR, Bearman GM, Wenzel RP, Edmond MB. Comparison of the systemic inflammatory response syndrome between monomicrobial and polymicrobial Pseudomonas aeruginosa nosocomial bloodstream infections. BMC Infect Dis 5: 94, 2005.
22. McKenzie FE. Case mortality in polymicrobial bloodstream infections. J Clin Epidemiol 59: 760-761, 2006.
23. Zelenitsky SA, Harding GK, Sun S, Ubhi K, Ariano RE. Treatment and outcome of Pseudomonas aeruginosa bacteraemia: an antibiotic pharmacodynamic analysis. J Antimicrob Chemother 52: 668-674, 2003.
24. Horino T. Prognostic factors and the role of interleukin-1 in bacteremia caused by Pseudomonas aeruginosa. Jpn J Chemother 58: 547-554, 2010 (in Japanese, Abstract in English).