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Volumn 32, Issue SUPPL. 1, 2012, Pages 64-73

Response-guided and -unguided treatment of chronic hepatitis C

Author keywords

HCV; Hepatitis C; Protease inhibitor; Response guided therapy

Indexed keywords

BOCEPREVIR; INTERLEUKIN 28B; PEGINTERFERON; PROTEINASE INHIBITOR; RIBAVIRIN; TELAPREVIR; VIRUS RNA;

EID: 84855219530     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2011.02713.x     Document Type: Review
Times cited : (12)

References (44)
  • 1
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial
    • Manns MP, McHutchison JG, Gordon SC, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358: 958-65.
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 2
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002; 347: 975-82.
    • (2002) N Engl J Med , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 3
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose
    • Hadziyannis SJ, Sette H, Jr., Morgan TR, et al. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004; 140: 346-55.
    • (2004) Ann Intern Med , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1    Sette Jr., H.2    Morgan, T.R.3
  • 4
    • 84860390172 scopus 로고    scopus 로고
    • Reduced dose and duration of peginterferon alfa-2b and weight-based ribavirin in patients with genotype 2 and 3 chronic hepatitis C
    • Manns M, Zeuzem S, Sood A, et al. Reduced dose and duration of peginterferon alfa-2b and weight-based ribavirin in patients with genotype 2 and 3 chronic hepatitis C. J Hepatol 2011; 55: 554-63.
    • (2011) J Hepatol , vol.55 , pp. 554-563
    • Manns, M.1    Zeuzem, S.2    Sood, A.3
  • 5
    • 33645992473 scopus 로고    scopus 로고
    • Extended treatment duration for hepatitis C virus type 1: comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin
    • Berg T, von Wagner M, Nasser S, et al. Extended treatment duration for hepatitis C virus type 1: comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin. Gastroenterology 2006; 130: 1086-97.
    • (2006) Gastroenterology , vol.130 , pp. 1086-1097
    • Berg, T.1    von Wagner, M.2    Nasser, S.3
  • 6
    • 33746564989 scopus 로고    scopus 로고
    • Peginterferon-alfa2a plus ribavirin for 48 versus 72 weeks in patients with detectable hepatitis C virus RNA at week 4 of treatment
    • Sanchez-Tapias JM, Diago M, Escartin P, et al. Peginterferon-alfa2a plus ribavirin for 48 versus 72 weeks in patients with detectable hepatitis C virus RNA at week 4 of treatment. Gastroenterology 2006; 131: 451-60.
    • (2006) Gastroenterology , vol.131 , pp. 451-460
    • Sanchez-Tapias, J.M.1    Diago, M.2    Escartin, P.3
  • 7
    • 37749051824 scopus 로고    scopus 로고
    • Treatment extension to 72 weeks of peginterferon and ribavirin in hepatitis c genotype 1-infected slow responders
    • Pearlman BL, Ehleben C, Saifee S. Treatment extension to 72 weeks of peginterferon and ribavirin in hepatitis c genotype 1-infected slow responders. Hepatology 2007; 46: 1688-94.
    • (2007) Hepatology , vol.46 , pp. 1688-1694
    • Pearlman, B.L.1    Ehleben, C.2    Saifee, S.3
  • 8
    • 38649090347 scopus 로고    scopus 로고
    • Individualized treatment duration for hepatitis C genotype 1 patients: a randomized controlled trial
    • Mangia A, Minerva N, Bacca D, et al. Individualized treatment duration for hepatitis C genotype 1 patients: a randomized controlled trial. Hepatology 2008; 47: 43-50.
    • (2008) Hepatology , vol.47 , pp. 43-50
    • Mangia, A.1    Minerva, N.2    Bacca, D.3
  • 9
    • 46249114151 scopus 로고    scopus 로고
    • Rapid virological response and treatment duration for chronic hepatitis C genotype 1 patients: a randomized trial
    • Yu ML, Dai CY, Huang JF, et al. Rapid virological response and treatment duration for chronic hepatitis C genotype 1 patients: a randomized trial. Hepatology 2008; 47: 1884-93.
    • (2008) Hepatology , vol.47 , pp. 1884-1893
    • Yu, M.L.1    Dai, C.Y.2    Huang, J.F.3
  • 10
    • 68949183162 scopus 로고    scopus 로고
    • Individualized treatment strategy according to early viral kinetics in hepatitis C virus type 1-infected patients
    • Berg T, Weich V, Teuber G, et al. Individualized treatment strategy according to early viral kinetics in hepatitis C virus type 1-infected patients. Hepatology 2009; 50: 369-77.
    • (2009) Hepatology , vol.50 , pp. 369-377
    • Berg, T.1    Weich, V.2    Teuber, G.3
  • 11
    • 77957952655 scopus 로고    scopus 로고
    • Randomized trial of peginterferon alfa-2b and ribavirin for 48 or 72 weeks in patients with hepatitis C virus genotype 1 and slow virologic response
    • Buti M, Lurie Y, Zakharova NG, et al. Randomized trial of peginterferon alfa-2b and ribavirin for 48 or 72 weeks in patients with hepatitis C virus genotype 1 and slow virologic response. Hepatology 2010; 52: 1201-7.
    • (2010) Hepatology , vol.52 , pp. 1201-1207
    • Buti, M.1    Lurie, Y.2    Zakharova, N.G.3
  • 12
    • 75449111848 scopus 로고    scopus 로고
    • Peginterferon alfa-2a/ribavirin for 48 or 72 weeks in hepatitis C genotypes 1 and 4 patients with slow virologic response
    • 12 e1.
    • Ferenci P, Laferl H, Scherzer TM, et al. Peginterferon alfa-2a/ribavirin for 48 or 72 weeks in hepatitis C genotypes 1 and 4 patients with slow virologic response. Gastroenterology 2010; 138: 503-12, 12 e1.
    • (2010) Gastroenterology , vol.138 , pp. 503-512
    • Ferenci, P.1    Laferl, H.2    Scherzer, T.M.3
  • 13
    • 38649090068 scopus 로고    scopus 로고
    • Pegylated interferon alfa and ribavirin for 14 versus 24 weeks in patients with hepatitis C virus genotype 2 or 3 and rapid virological response
    • Dalgard O, Bjoro K, Ring-Larsen H, et al. Pegylated interferon alfa and ribavirin for 14 versus 24 weeks in patients with hepatitis C virus genotype 2 or 3 and rapid virological response. Hepatology 2008; 47: 35-42.
    • (2008) Hepatology , vol.47 , pp. 35-42
    • Dalgard, O.1    Bjoro, K.2    Ring-Larsen, H.3
  • 14
    • 46249129460 scopus 로고    scopus 로고
    • Randomized comparison of 12 or 24 weeks of peginterferon alpha-2a and ribavirin in chronic hepatitis C virus genotype 2/3 infection
    • Lagging M, Langeland N, Pedersen C, et al. Randomized comparison of 12 or 24 weeks of peginterferon alpha-2a and ribavirin in chronic hepatitis C virus genotype 2/3 infection. Hepatology 2008; 47: 1837-45.
    • (2008) Hepatology , vol.47 , pp. 1837-1845
    • Lagging, M.1    Langeland, N.2    Pedersen, C.3
  • 15
    • 34447318385 scopus 로고    scopus 로고
    • Peginterferon alfa-2a and ribavirin for 16 or 24 weeks in HCV genotype 2 or 3
    • Shiffman ML, Suter F, Bacon BR, et al. Peginterferon alfa-2a and ribavirin for 16 or 24 weeks in HCV genotype 2 or 3. N Engl J Med 2007; 357: 124-34.
    • (2007) N Engl J Med , vol.357 , pp. 124-134
    • Shiffman, M.L.1    Suter, F.2    Bacon, B.R.3
  • 16
    • 21044444857 scopus 로고    scopus 로고
    • A randomized controlled trial of pegylated interferon alpha-2a (40 KD) or interferon alpha-2a plus ribavirin and amantadine vs interferon alpha-2a and ribavirin in treatment-naive patients with chronic hepatitis C
    • Mangia A, Ricci GL, Persico M, et al. A randomized controlled trial of pegylated interferon alpha-2a (40 KD) or interferon alpha-2a plus ribavirin and amantadine vs interferon alpha-2a and ribavirin in treatment-naive patients with chronic hepatitis C. J Viral Hepat 2005; 12: 292-9.
    • (2005) J Viral Hepat , vol.12 , pp. 292-299
    • Mangia, A.1    Ricci, G.L.2    Persico, M.3
  • 17
    • 23244457832 scopus 로고    scopus 로고
    • Peginterferon-alpha-2a (40KD) and ribavirin for 16 or 24 weeks in patients with genotype 2 or 3 chronic hepatitis C
    • von Wagner M, Huber M, Berg T, et al. Peginterferon-alpha-2a (40KD) and ribavirin for 16 or 24 weeks in patients with genotype 2 or 3 chronic hepatitis C. Gastroenterology 2005; 129: 522-7.
    • (2005) Gastroenterology , vol.129 , pp. 522-527
    • von Wagner, M.1    Huber, M.2    Berg, T.3
  • 18
    • 33646590308 scopus 로고    scopus 로고
    • Early identification of HCV genotype 1 patients responding to 24 weeks peginterferon alpha-2a (40 kd)/ribavirin therapy
    • Jensen DM, Morgan TR, Marcellin P, et al. Early identification of HCV genotype 1 patients responding to 24 weeks peginterferon alpha-2a (40 kd)/ribavirin therapy. Hepatology 2006; 43: 954-60.
    • (2006) Hepatology , vol.43 , pp. 954-960
    • Jensen, D.M.1    Morgan, T.R.2    Marcellin, P.3
  • 19
    • 80054846451 scopus 로고    scopus 로고
    • Improved Responses to Pegylated Interferon Alfa-2b and Ribavirin by Individualizing Treatment for 24-72 Weeks
    • Sarrazin C, Schwendy S, Moller B, et al. Improved Responses to Pegylated Interferon Alfa-2b and Ribavirin by Individualizing Treatment for 24-72 Weeks. Gastroenterology 2011; 141: 1656-64.
    • (2011) Gastroenterology , vol.141 , pp. 1656-1664
    • Sarrazin, C.1    Schwendy, S.2    Moller, B.3
  • 20
    • 79959438789 scopus 로고    scopus 로고
    • Telaprevir for previously untreated chronic hepatitis C virus infection
    • Jacobson IM, McHutchison JG, Dusheiko G, et al. Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 2011; 364: 2405-16.
    • (2011) N Engl J Med , vol.364 , pp. 2405-2416
    • Jacobson, I.M.1    McHutchison, J.G.2    Dusheiko, G.3
  • 21
    • 23444460553 scopus 로고    scopus 로고
    • Predicting sustained virological responses in chronic hepatitis C patients treated with peginterferon alfa-2a (40 KD)/ribavirin
    • Ferenci P, Fried MW, Shiffman ML, et al. Predicting sustained virological responses in chronic hepatitis C patients treated with peginterferon alfa-2a (40 KD)/ribavirin. J Hepatol 2005; 43: 425-33.
    • (2005) J Hepatol , vol.43 , pp. 425-433
    • Ferenci, P.1    Fried, M.W.2    Shiffman, M.L.3
  • 22
    • 79958816097 scopus 로고    scopus 로고
    • Rapid virological response is the most important predictor of sustained virological response across genotypes in patients with chronic hepatitis C virus infection
    • Fried MW, Hadziyannis SJ, Shiffman ML, Messinger D, Zeuzem S. Rapid virological response is the most important predictor of sustained virological response across genotypes in patients with chronic hepatitis C virus infection. J Hepatol 2011; 55: 69-75.
    • (2011) J Hepatol , vol.55 , pp. 69-75
    • Fried, M.W.1    Hadziyannis, S.J.2    Shiffman, M.L.3    Messinger, D.4    Zeuzem, S.5
  • 23
    • 80052024078 scopus 로고    scopus 로고
    • Response-guided peg-interferon plus ribavirin treatment duration in chronic hepatitis C: Meta-analyses of randomized, controlled trials and implications for the future
    • epub ahead of print]
    • Di Martino V, Richou C, Cervoni JP, et al. Response-guided peg-interferon plus ribavirin treatment duration in chronic hepatitis C: Meta-analyses of randomized, controlled trials and implications for the future. Hepatology 2011 [epub ahead of print].
    • (2011) Hepatology
    • Di Martino, V.1    Richou, C.2    Cervoni, J.P.3
  • 24
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for previously treated chronic HCV genotype 1 infection
    • Bacon BR, Gordon SC, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011; 364: 1207-17.
    • (2011) N Engl J Med , vol.364 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 25
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J, Jr., Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364: 1195-206.
    • (2011) N Engl J Med , vol.364 , pp. 1195-1206
    • Poordad, F.1    McCone Jr., J.2    Bacon, B.R.3
  • 26
    • 80052826527 scopus 로고    scopus 로고
    • Response-guided telaprevir combination treatment for hepatitis C virus infection
    • Sherman KE, Flamm SL, Afdhal NH, et al. Response-guided telaprevir combination treatment for hepatitis C virus infection. N Engl J Med 2011; 365: 1014-24.
    • (2011) N Engl J Med , vol.365 , pp. 1014-1024
    • Sherman, K.E.1    Flamm, S.L.2    Afdhal, N.H.3
  • 27
    • 80052116134 scopus 로고    scopus 로고
    • Telaprevir alone or with peginterferon and ribavirin reduces HCV RNA in patients with chronic genotype 2 but not genotype 3 infections
    • e1.
    • Foster GR, Hezode C, Bronowicki JP, et al. Telaprevir alone or with peginterferon and ribavirin reduces HCV RNA in patients with chronic genotype 2 but not genotype 3 infections. Gastroenterology 2011; 141: 881-9, e1.
    • (2011) Gastroenterology , vol.141 , pp. 881-889
    • Foster, G.R.1    Hezode, C.2    Bronowicki, J.P.3
  • 28
    • 84984562129 scopus 로고    scopus 로고
    • Pegylated interferon-alpha-2a plus ribavirin for treatment-naive Asian patients with hepatitis C virus genotype 1 infection: a multicenter, randomized controlled trial
    • Liu CH, Liu CJ, Lin CL, et al. Pegylated interferon-alpha-2a plus ribavirin for treatment-naive Asian patients with hepatitis C virus genotype 1 infection: a multicenter, randomized controlled trial. Clin Infect Dis 2008; 47: 1260-9.
    • (2008) Clin Infect Dis , vol.47 , pp. 1260-1269
    • Liu, C.H.1    Liu, C.J.2    Lin, C.L.3
  • 29
    • 28844451934 scopus 로고    scopus 로고
    • Efficacy of 24 weeks treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia
    • Zeuzem S, Buti M, Ferenci P, et al. Efficacy of 24 weeks treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia. J Hepatol 2006; 44: 97-103.
    • (2006) J Hepatol , vol.44 , pp. 97-103
    • Zeuzem, S.1    Buti, M.2    Ferenci, P.3
  • 30
    • 78650973933 scopus 로고    scopus 로고
    • IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: the future of personalized HCV therapies
    • Clark PJ, Thompson AJ, McHutchison JG. IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: the future of personalized HCV therapies. Am J Gastroenterol 2011; 106: 38-45.
    • (2011) Am J Gastroenterol , vol.106 , pp. 38-45
    • Clark, P.J.1    Thompson, A.J.2    McHutchison, J.G.3
  • 31
    • 77953881002 scopus 로고    scopus 로고
    • Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus
    • e18.
    • Thompson AJ, Muir AJ, Sulkowski MS, et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology 2010; 139: 120-9, e18.
    • (2010) Gastroenterology , vol.139 , pp. 120-129
    • Thompson, A.J.1    Muir, A.J.2    Sulkowski, M.S.3
  • 32
    • 33746535101 scopus 로고    scopus 로고
    • Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1
    • Conjeevaram HS, Fried MW, Jeffers LJ, et al. Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1. Gastroenterology 2006; 131: 470-7.
    • (2006) Gastroenterology , vol.131 , pp. 470-477
    • Conjeevaram, H.S.1    Fried, M.W.2    Jeffers, L.J.3
  • 33
    • 79959381354 scopus 로고    scopus 로고
    • Telaprevir for retreatment of HCV infection
    • Zeuzem S, Andreone P, Pol S, et al. Telaprevir for retreatment of HCV infection. N Engl J Med 2011; 364: 2417-28.
    • (2011) N Engl J Med , vol.364 , pp. 2417-2428
    • Zeuzem, S.1    Andreone, P.2    Pol, S.3
  • 34
    • 34247594930 scopus 로고    scopus 로고
    • Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir
    • Sarrazin C, Kieffer TL, Bartels D, et al. Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir. Gastroenterology 2007; 132: 1767-77.
    • (2007) Gastroenterology , vol.132 , pp. 1767-1777
    • Sarrazin, C.1    Kieffer, T.L.2    Bartels, D.3
  • 35
    • 73149113353 scopus 로고    scopus 로고
    • Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients
    • Susser S, Welsch C, Wang Y, et al. Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients. Hepatology 2009; 50: 1709-18.
    • (2009) Hepatology , vol.50 , pp. 1709-1718
    • Susser, S.1    Welsch, C.2    Wang, Y.3
  • 36
    • 65449171953 scopus 로고    scopus 로고
    • Telaprevir and peginterferon with or without ribavirin for chronic HCV infection
    • Hezode C, Forestier N, Dusheiko G, et al. Telaprevir and peginterferon with or without ribavirin for chronic HCV infection. N Engl J Med 2009; 360: 1839-50.
    • (2009) N Engl J Med , vol.360 , pp. 1839-1850
    • Hezode, C.1    Forestier, N.2    Dusheiko, G.3
  • 37
    • 20544443172 scopus 로고    scopus 로고
    • Peginterferon alfa-2b and ribavirin for 12 vs. 24 weeks in HCV genotype 2 or 3
    • Mangia A, Santoro R, Minerva N, et al. Peginterferon alfa-2b and ribavirin for 12 vs. 24 weeks in HCV genotype 2 or 3. N Engl J Med 2005; 352: 2609-17.
    • (2005) N Engl J Med , vol.352 , pp. 2609-2617
    • Mangia, A.1    Santoro, R.2    Minerva, N.3
  • 38
    • 77951907720 scopus 로고    scopus 로고
    • Short versus standard treatment with pegylated interferon alfa-2A plus ribavirin in patients with hepatitis C virus genotype 2 or 3: the cleo trial
    • Mecenate F, Pellicelli AM, Barbaro G, et al. Short versus standard treatment with pegylated interferon alfa-2A plus ribavirin in patients with hepatitis C virus genotype 2 or 3: the cleo trial. BMC Gastroenterol 2010; 10: 21.
    • (2010) BMC Gastroenterol , vol.10 , pp. 21
    • Mecenate, F.1    Pellicelli, A.M.2    Barbaro, G.3
  • 39
    • 84925580987 scopus 로고    scopus 로고
    • An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response
    • 7 e1.
    • Mangia A, Thompson AJ, Santoro R, et al. An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response. Gastroenterology 2010; 139: 821-7, 7 e1.
    • (2010) Gastroenterology , vol.139 , pp. 821-827
    • Mangia, A.1    Thompson, A.J.2    Santoro, R.3
  • 40
    • 42249110672 scopus 로고    scopus 로고
    • Hepatitis C genotype 4: what we know and what we don't yet know
    • Kamal SM, Nasser IA. Hepatitis C genotype 4: what we know and what we don't yet know. Hepatology 2008; 47: 1371-83.
    • (2008) Hepatology , vol.47 , pp. 1371-1383
    • Kamal, S.M.1    Nasser, I.A.2
  • 41
    • 21144449073 scopus 로고    scopus 로고
    • Peginterferon {alpha}-2b and ribavirin therapy in chronic hepatitis C genotype 4: impact of treatment duration and viral kinetics on sustained virological response
    • Kamal SM, El Tawil AA, Nakano T, et al. Peginterferon {alpha}-2b and ribavirin therapy in chronic hepatitis C genotype 4: impact of treatment duration and viral kinetics on sustained virological response. Gut 2005; 54: 858-66.
    • (2005) Gut , vol.54 , pp. 858-866
    • Kamal, S.M.1    El Tawil, A.A.2    Nakano, T.3
  • 42
    • 37749046123 scopus 로고    scopus 로고
    • Pegylated interferon alpha-2b plus ribavirin in patients with genotype 4 chronic hepatitis C: the role of rapid and early virologic response
    • Kamal SM, El Kamary SS, Shardell MD, et al. Pegylated interferon alpha-2b plus ribavirin in patients with genotype 4 chronic hepatitis C: the role of rapid and early virologic response. Hepatology 2007; 46: 1732-40.
    • (2007) Hepatology , vol.46 , pp. 1732-1740
    • Kamal, S.M.1    El Kamary, S.S.2    Shardell, M.D.3
  • 43
    • 48749099989 scopus 로고    scopus 로고
    • Peginterferon alfa-2a and ribavirin for 24 weeks in hepatitis C type 1 and 4 patients with rapid virological response
    • Ferenci P, Laferl H, Scherzer TM, et al. Peginterferon alfa-2a and ribavirin for 24 weeks in hepatitis C type 1 and 4 patients with rapid virological response. Gastroenterology 2008; 135: 451-8.
    • (2008) Gastroenterology , vol.135 , pp. 451-458
    • Ferenci, P.1    Laferl, H.2    Scherzer, T.M.3
  • 44
    • 84855247270 scopus 로고    scopus 로고
    • IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C
    • in press.
    • Asselah T, De Muynck S, Broet P, et al. IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C. J Hepatol 2011; in press.
    • (2011) J Hepatol
    • Asselah, T.1    De Muynck, S.2    Broet, P.3


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