Autologous platelet-rich plasma gel to reduce donor-site morbidity after patellar tendon graft harvesting for anterior cruciate ligament reconstruction: A randomized, controlled clinical study

Knee Surgery, Sports Traumatology, Arthroscopy

Volumn 20, Issue 1, 2012, Pages 114-120

  Cervellin, M ^a   de Girolamo, L ^b   Bait, C ^a   Denti, M ^a   Volpi, P ^a  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b IRCCS ISTITUTO ORTOPEDICO GALEAZZI   (Italy)

Author keywords

Anterior cruciate ligament reconstruction; Athletes; Bone patellar tendon bone graft; Donor site morbidity; Platelet rich plasma

Indexed keywords

ADULT; ANTERIOR CRUCIATE LIGAMENT; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ARTICLE; BONE PATELLAR TENDON BONE GRAFT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVALESCENCE; FEMALE; FOLLOW UP; GEL; HUMAN; INJURY; KNEE INJURY; MALE; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PAIN ASSESSMENT; PATHOPHYSIOLOGY; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE RICH PLASMA; TREATMENT OUTCOME; WOUND HEALING;

ADULT; ANTERIOR CRUCIATE LIGAMENT; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; BONE-PATELLAR TENDON-BONE GRAFT; FEMALE; FOLLOW-UP STUDIES; GELS; HUMANS; KNEE INJURIES; MAGNETIC RESONANCE IMAGING; MALE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PLATELET-RICH PLASMA; RECOVERY OF FUNCTION; TREATMENT OUTCOME; WOUND HEALING;

EID: 84855205073     PISSN: 09422056     EISSN: 14337347     Source Type: Journal    
DOI: 10.1007/s00167-011-1570-5     Document Type: Article

References (27)

1. Ahmed TA, Dare EV, Hincke M (2008) Fibrin: a versatile scaffold for tissue engineering applications. Tissue Eng Part B Rev 14: 199-215.
2. Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT (2004) Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 91: 4-15.
3. Anitua E, Andía I, Sanchez M, Azofra J, del Mar Zalduendo M, de la Fuente M, Nurden P, Nurden AT (2005) Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Ortho Res 23: 281-286.
4. Ardern CL, Webster KE, Taylor NF, Feller JA (2011) Return to sport following anterior cruciate ligament reconstruction surgery: a systematic review and meta-analysis of the state of play. Br J Sports Med 45: 596-606.
5. Arnoczky SP, Anderson L, Fanelli G, Ho S, Mishra A, Sgaglione N (2009) The role of platelet-rich plasma in connective tissue repair. Orthopedics Today 26: 29. www. orthosupersite. com/view. asp?rid_37598.
6. Bibbo C, Hatfield PS (2010) Platelet-rich plasma concentrate to augment bone fusion. Foot Ankle Clin 15: 641-649.
7. Carey JL, Dunn WR, Dahn DL, Zeger SL, Spindler KP (2009) A systematic review of anterior cruciate ligament reconstruction with autograft compared with allograft. J Bone Joint Surg Am 91: 2242-2250.
8. Foster TE, Puskas BL, Mandelbaum BR, Gerhardt MB, Rodeo SA (2009) Platelet-rich plasma: from basic science to clinical applications. Am J Sports Med 37: 2259-2272.
9. Kanakaris NK, Lasanianos N, Calori GM, Verdonk R, Blokhuis TJ, Cherubino P, De Biase P, Giannoudis PV (2009) Application of bone morphogenetic proteins to femoral non-unions: a 4-year multicentre experience. Injury 40(Suppl 3): S54-S61.
10. Kartus J, Magnusson L, Stener S, Brandsson S, Eriksson BI, Karlsson J (1999) Complications following arthroscopic anterior cruciate ligament reconstruction. A 2-5-year follow-up of 604 patients with special emphasis on anterior knee pain. Knee Surg Sports Traumatol Arthrosc 7: 2-8.
11. Kartus J, Stener S, Lindahl S, Engstrom B, Eriksson BI, Karlsson J (1997) Factors affecting donor-site morbidity after anterior cruciate ligament reconstruction using bone-patellar tendon-bone autografts. Knee Surg Sports Traumatol Arthrosc 5: 222-228.
12. Kohn D, Sander-Beuermann A (1994) Donor-site morbidity after harvest of a bone-tendon-bone patellar tendon autograft. Knee Surg Sports Traumatol Arthrosc 2: 219-223.
13. Lopez-Vidriero E, Goulding KA, Simon DA, Sanchez M, Johnson DH (2010) The use of platelet-rich plasma in arthroscopy and sports medicine: optimizing the healing environment. Arthroscopy 26: 269-278.
14. Mishra A, Pavelko T (2006) Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. A J Sports Med 34: 1774-1778.
15. Mishra A, Woodall J Jr, Vieira A (2009) Treatment of tendon and muscle using platelet-rich plasma. Clin Sports Med 28: 113-125.
16. Nin JR, Gasque GM, Azcárate AV, Beola JD, Gonzalez MH (2009) Has platelet-rich plasma any role in anterior cruciate ligament allograft healing? Arthroscopy 25: 1206-1213.
17. Pneumaticos SG, Triantafyllopoulos GK, Chatziioannou S, Basdra EK, Papavassiliou AG (2010) Biomolecular strategies of bone augmentation in spinal surgery. Trends Mol Med 17: 215-222.
18. Radice F, Gutierrez V, Ibarra A, Verdugo A (1998) Arthroscopic, histologic and MRI correlation in the maturation process of the graft in ACL reconstruction in humans. Arthroscopy 14: S20 (Suppl 1).
19. Radice F, Yánez R, Gutiérrez V, Rosales J, Pinedo M, Coda S (2010) Comparison of magnetic resonance imaging findings in anterior cruciate ligament grafts with and without autologous platelet-derived growth factors. Arthroscopy 26: 50-57.
20. Sachs RA, Daniel DM, Stone ML, Garfein RF (1989) Patellofemoral problems after anterior cruciate ligament reconstruction. Am J Sports Med 17: 760-765.
21. Sanchez M, Anitua E, Azofra J, Andia I, Padilla S, Mujika I (2007) Comparison of surgically repaired achilles tendon tears using platelet-rich fibrin matrices. Am J Sports Med 35: 245-251.
22. Sánchez M, Anitua E, Azofra J, Prado R, Muruzabal F, Andia I (2010) Ligamentization of tendon grafts treated with an endogenous preparation rich in growth factors: gross morphology and histology. Arthroscopy 26: 470-480.
23. Sanchez M, Azofra J, Aizpurua B, Elorriaga R, Anitua E, Andia I (2003) Use of autologous plasma rich in growth factors in arthroscopic surgery. Cuad Artrosc 10: 12-19.
24. Shelbourne KD, Trumper RV (1997) Preventing anterior knee pain after anterior cruciate ligament reconstruction. Am J Sports Med 25: 41-47.
25. Silva A, Sampaio R (2009) Anatomic ACL reconstruction: does the platelet-rich plasma accelerate tendon healing? Knee Surg Sports Traumatol Arthrosc 17: 676-682.
26. Visentini PJ, Khan KM, Cook JL, Kiss ZS, Harcourt PR, Wark JD (1998) The VISA score: an index of severity of symptoms in patients with jumper's knee (patellar tendinosis). Victorian Institute of Sport Tendon Study Group. J Sci Med Sport 1: 22-28.
27. Zhang J, Wang JH (2010) Platelet-rich plasma releasate promotes differentiation of tendon stem cells into active tenocytes. Am J Sports Med 38: 2477-2486.