Characteristics of optical coherence tomographic hyperreflective foci in retinal vein occlusion

Retina

Volumn 32, Issue 1, 2012, Pages 77-85

  Ogino, Ken ^a   Murakami, Tomoaki ^a   Tsujikawa, Akitaka ^a   Miyamoto, Kazuaki ^a   Sakamoto, Atsushi ^a   Ota, Masafumi ^a   Yoshimura, Nagahisa ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

external limiting membrane; hard exudates; hyperreflective foci; optical coherence tomography; outer plexiform layer; retinal vein occlusion; serous retinal detachment

Indexed keywords

AGED; ARTICLE; CENTRAL RETINA VEIN OCCLUSION; DIABETIC MACULAR EDEMA; EXTRAVASATION; EXUDATE; FEMALE; FLUORESCENCE ANGIOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; MEDICAL PHOTOGRAPHY; MEDICAL RECORD REVIEW; OPHTHALMOSCOPY; OPTICAL COHERENCE TOMOGRAPHY; PATHOGENESIS; RETINA DETACHMENT; RETINA VEIN OCCLUSION; RETROSPECTIVE STUDY;

AGED; COLOR; DIABETIC RETINOPATHY; EXUDATES AND TRANSUDATES; FEMALE; FLUORESCEIN ANGIOGRAPHY; FOVEA CENTRALIS; HUMANS; MACULAR EDEMA; MALE; MIDDLE AGED; RETINAL VEIN OCCLUSION; RETROSPECTIVE STUDIES; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84855201906     PISSN: 0275004X     EISSN: 15392864     Source Type: Journal    
DOI: 10.1097/IAE.0b013e318217ffc7     Document Type: Article

References (26)

1. Argon laser photocoagulation for macular edema in branch vein occlusion. The Branch Vein Occlusion Study Group. Am J Ophthalmol 1984;98:271-282.
2. Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Early Treatment Diabetic Retinopathy Study research group. Arch Ophthalmol 1985;103:1796-1806.
3. Tsujikawa A, Sakamoto A, Ota M, et al. Retinal structural changes associated with retinal arterial macroaneurysm examined with optical coherence tomography. Retina 2009; 29:782-792.
4. Feng Y, Venema VJ, Venema RC, et al. VEGF-induced permeability increase is mediated by caveolae. Invest Ophthalmol Vis Sci 1999;40:157-167. (Pubitemid 29029584)
5. Dvorak AM, Feng D. The vesiculo-vacuolar organelle (VVO). A new endothelial cell permeability organelle. J Histochem Cytochem 2001;49:419-432.
6. Vinores SA, Derevjanik NL, Ozaki H, et al. Cellular mechanisms of blood-retinal barrier dysfunction in macular edema. Doc Ophthalmol 1999;97:217-228.
7. Antonetti DA, Lieth E, Barber AJ, Gardner TW. Molecular mechanisms of vascular permeability in diabetic retinopathy. Semin Ophthalmol 1999;14:240-248. (Pubitemid 30061167)
8. Chew EY, Klein ML, Ferris FL III, et al. Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy. Early Treatment Diabetic Retinopathy Study (ETDRS) Report 22. Arch Ophthalmol 1996;114:1079-1084.
9. Toussaint D, Cogan DG, Kuwabara T. Extravascular lesions of diabetic retinopathy. Arch Ophthalmol 1962;67:42-47.
10. Fong DS, Segal PP, Myers F, et al. Subretinal fibrosis in diabetic macular edema. ETDRS report 23. Early Treatment Diabetic Retinopathy Study Research Group. Arch Ophthal-mol 1997;115:873-877.
11. Cusick M, Chew EY, Chan CC, et al. Histopathology and regression of retinal hard exudates in diabetic retinopathy after reduction of elevated serum lipid levels. Ophthalmology 2003; 110:2126-2133. (Pubitemid 37337848)
12. Takagi H, Otani A, Kiryu J, Ogura Y. New surgical approach for removing massive foveal hard exudates in diabetic macular edema. Ophthalmology 1999;106:249-256; discussion 256-257.
13. Larsson J, Kifley A, Zhu M, et al. Rapid reduction of hard exudates in eyes with diabetic retinopathy after intravitreal triamcinolone: data from a randomized, placebo-controlled, clinical trial. Acta Ophthalmol 2009;87:275-280.
14. Bolz M, Schmidt-Erfurth U, Deak G, et al. Optical coherence tomographic hyperreflective foci: a morphologic sign of lipid extravasation in diabetic macular edema. Ophthalmology 2009;116:914-920.
15. Deak GG, Bolz M, Kriechbaum K, et al. Effect of retinal photocoagulation on intraretinal lipid exudates in diabetic macular edema documented by optical coherence tomography. Ophthalmology 2010;117:773-779.
16. Drexler W, Fujimoto JG. State-of-the-art retinal optical coherence tomography. Prog Retin Eye Res 2008;27:45-88. (Pubitemid 351165776)
17. Spaide RF, Lee JK, Klancnik JK Jr, Gross NE. Optical coherence tomography of branch retinal vein occlusion. Retina 2003;23:343-347. (Pubitemid 36792979)
18. Iwasaki M, Inomata H. Relation between superficial capillaries and foveal structures in the human retina. Invest Ophthalmol Vis Sci 1986;27:1698-1705. (Pubitemid 17207841)
19. Tso MO. Pathology of cystoid macular edema. Ophthalmology 1982;89:902-915. (Pubitemid 12019474)
20. Wolter JR. The histopathology of cystoid macular edema. Graefes Arch Klin Exp Ophthalmol 1981;216:85-101. (Pubitemid 11113056)
21. Finkelstein D. Ischemic macular edema. Recognition and favorable natural history in branch vein occlusion. Arch Ophthalmol 1992;110:1427-1434.
22. Gardner TW, Antonetti DA, Barber AJ, et al. Diabetic retinopathy: more than meets the eye. Surv Ophthalmol 2002;47:S253-S262. (Pubitemid 36351245)
23. Tso MO, Cunha-Vaz JG, Shih CY, Jones CW. Clinicopatho-logic study of blood-retinal barrier in experimental diabetes mellitus. Arch Ophthalmol 1980;98:2032-2040. (Pubitemid 11250662)
24. Brown GC. Central retinal vein obstruction with lipid exudate. Arch Ophthalmol 1989;107:1001-1005. (Pubitemid 19183657)
25. Marmor MF. Mechanisms of fluid accumulation in retinal edema. Doc Ophthalmol 1999;97:239-249.
26. Bunt-Milam AH, Saari JC, Klock IB, Garwin GG. Zonulae adherentes pore size in the external limiting membrane of the rabbit retina. Invest Ophthalmol Vis Sci 1985;26: 1377-1380. (Pubitemid 15241062)