Predictive event modelling in multicenter clinical trials with waiting time to response

Pharmaceutical Statistics

Volumn 10, Issue 6, 2011, Pages 517-522

  Anisimov, Vladimir V ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

estimation; Event modeling; Markov model; multicenter clinical trial; Poisson gamma recruitment model; prediction

Indexed keywords

ARTICLE; HUMAN; MULTICENTER STUDY (TOPIC); PATIENT SELECTION; POISSON DISTRIBUTION; PREDICTION; PREDICTIVE EVENT MODELLING; STATISTICAL ANALYSIS;

BAYES THEOREM; CLINICAL TRIALS AS TOPIC; HUMANS; MARKOV CHAINS; MODELS, STATISTICAL; MULTICENTER STUDIES AS TOPIC; PATIENT SELECTION; TIME FACTORS;

EID: 84855193047     PISSN: 15391604     EISSN: 15391612     Source Type: Journal    
DOI: 10.1002/pst.525     Document Type: Article

References (14)

1. Senn S,. Statistical Issues in Drug Development. John Wiley & Sons: Chichester, 1997.
2. Senn S,. Some controversies in planning and analysis multi-centre trials. Statistics in Medicine 1998; 17: 1753-1756.
3. Carter RE,. Application of stochastic processes to participant recruitment in clinical trials. Controlled Clinical Trials 2004; 25: 429-436. (Pubitemid 39299153)
4. Carter RE, Sonne SC, Brady KT,. Practical considerations for estimating clinical trial accrual periods: application to a multi-center effectiveness study. BMC Medical Research Methodology 2005; 5: 11.
5. Bagiella E, Heitjan DF,. Predicting analysis times in randomized clinical trials. Statistics in Medicine 2001; 20: 2055-2063. (Pubitemid 32684628)
6. Donovan JM, Elliott MR, Heitjan DF,. Predicting event times in clinical trials when randomization is masked and blocked. Clinical Trials 2007; 4: 481-490. (Pubitemid 350189872)
7. Ying GS, Heitjan DF, Chen TT,. Nonparametric prediction of event times in randomized clinical trials. Clinical Trials 2004; 1: 352-361.
8. Ying GS, Heitjan DF,. Weibull prediction of event times in clinical trials. Pharmaceutical Statistics 2008; 7: 107-120. (Pubitemid 351943639)
9. Lachin JM,. Introduction to sample size determination and power analysis for clinical trials. Controlled Clinical Trials 1981; 2: 93-113. (Pubitemid 11006595)
10. Lachin JM, Foulkes MA,. Evaluation of sample size and power for analyses of survival with allowance for nonuniform patient entry, losses to follow-up, noncompiance and stratification. Biometrics 1986; 42: 507-519.
11. Crisp A, Curtis P,. Sample size estimation for noninferiority trials of time-to-event data. Pharmaceutical Statistics 2008; 7: 236-244.
12. Anisimov V, Fedorov V,. Modeling, prediction and adaptive adjustment of recruitment in multicentre trials. Statistics in Medicine 2007; 26 (27): 4958-4975. (Pubitemid 350064916)
13. Anisimov V,. Using mixed Poisson models in patient recruitment in multicentre clinical trials. Proceedings of the World Congress on Engineering 2008; II: 1046-1049.
14. Anisimov V,. Statistical modelling of clinical trials (recruitment and randomization). Communications in Statistics-Theory and Methods 2011; 40 (19/20): 3684-3699.