Some controversies in planning and analysing multi-centre trials

Statistics in Medicine

Volumn 17, Issue 15-16, 1998, Pages 1753-1765

  Senn, Stephen ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAY; CONFERENCE PAPER; MULTICENTER STUDY; PLANNING; STATISTICS;

EID: 0032529143     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0258(19980815/30)17:15/16<1753::aid-sim977>3.0.co;2-x     Document Type: Conference Paper

References (8)

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3. Speed, F. M., Hocking, R. R. and Hackney, O. P. 'Methods of analysis of linear models with unbalanced data', Journal of the American Statistical Association, 73, 105-112 (1978).
4. Nelder, J. 'A reformulation of linear models', Journal of the Royal Statistical Society, Series A, 140, 48-76 (1977).
5. Berry, D. A. 'Basic principles in designing and analysing clinical studies', in Berry, D. A. (ed.), Statistical Methodology in the Pharmaceutical Industry, Marcel Dekker, New York, 1990.
6. Fleiss, J. L. 'Analysis of data from multiclinic trials', Controlled Clinical Trials, 10, 237-243 (1986).
7. Senn, S. J. 'A personal view of some controversies in allocating treatment to patients in clinical trials', Statistics in Medicine, 14, 2661-2674 (1995).
8. Ward, P. 'Europe takes tentative steps to combat fraud', Applied Clinical Trials, 4, (9), 36-40 (1995).