A novel synthetic material for spinal fusion: A prospective clinical trial of porous bioactive titanium metal for lumbar interbody fusion

European Spine Journal

Volumn 20, Issue 9, 2011, Pages 1486-1495

  Fujibayashi, Shunsuke ^a   Takemoto, Mitsuru ^a   Neo, Masashi ^a   Matsushita, Tomiharu ^b   Kokubo, Tadashi ^b   Doi, Kenji ^c   Ito, Tatsuya ^d   Shimizu, Akira ^d   Nakamura, Takashi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b CHUBU UNIVERSITY   (Japan)

^c Osaka Yakin Kogyou CoLtd   (Japan)

^d KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Biomaterial; Clinical trial; Porous titanium metal; Spinal fusion

Indexed keywords

TITANIUM;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; DEVICE THERAPY; FEMALE; FOLLOW UP; FRACTURE HEALING; HUMAN; MALE; MECHANICAL TORSION; METAL IMPLANTATION; MULTIDETECTOR COMPUTED TOMOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; ORTHOPEDIC EQUIPMENT; POROSITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROSTHESIS MATERIAL; SPINE FUSION; SPONDYLOLISTHESIS; TREATMENT OUTCOME; VISUAL ANALOG SCALE; YOUNG MODULUS;

ADULT; FEMALE; HUMANS; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; PAIN MEASUREMENT; PATIENT SATISFACTION; PROSPECTIVE STUDIES; SPINAL FUSION; SPONDYLOLISTHESIS; TITANIUM; TREATMENT OUTCOME;

EID: 84855190857     PISSN: 09406719     EISSN: 14320932     Source Type: Journal    
DOI: 10.1007/s00586-011-1728-3     Document Type: Article

References (32)

1. Banwart JC, Asher MA, Hassanein RS (1995) Iliac crest bone graft harvest donor site morbidity. A statistical evaluation. Spine 20:1055-1060
2. Bloebaum RD, Beeks D, Dorr LD, Savory CG, DuPont J, Hofmann AA (1994) Complications with hydroxyapatite particulate separation in total hip arthroplasty. Clin Orthop 298:19-26 (Pubitemid 24023588)
3. Boden SD, Zdeblick TA, Sandu HS, Heim SE (2000) The use of rhBMP-2 in interbody fusion cages: definitive evidence of osteoinduction in humans: a preliminary report. Spine 25:376-381 (Pubitemid 30097051)
4. Brantigan JW, Cunningham BW, Warden K, McAfee PC, Steffee AD (1993) Compression strength of donor bone for posterior lumbar interbody fusion. Spine 18:1213-1221 (Pubitemid 23210773)
5. De Groot K, Geesink R, Klein CP, Serekian P (1987) Plasma sprayed coatings of hydroxyapatite. J Biomed Mater Res 21: 1375-1381
6. Desogus N, Ennas F, Leuze R et al (2005) Posterior lumbar interbody fusion with PEEK cages: personal experience with 20 patients. J Neurosurg Sci 49:137-141 (Pubitemid 43139588)
7. Ducheyne P, Qiu Q (1999) Bioactive ceramics: the effect of surface reactivity on bone formation and bone cell function. Biomaterials 20:2287-2303
8. Fujibayashi S, Shikata J, Tanaka C, Matsushita M, Nakamura T (2001) Lumbar posterolateral fusion with biphasic calcium phosphate ceramic. J Spinal Disord 14:214-221 (Pubitemid 32545086)
9. Fujibayashi S, Nakamura T, Nishiguchi S, Tamura J, Uchida M, Kim HM et al (2001) Bioactive titanium: effect of sodium removal on the bone-bonding ability of bioactive titanium prepared by alkali and heat treatment. J Biomed Mater Res 56:562-570 (Pubitemid 32606015)
10. Fujibayashi S, Neo M, Kim HM, Kokubo T, Nakamura T (2004) Osteoinduction of porous bioactive titanium metal. Biomaterials 25:443-450 (Pubitemid 37329695)
11. Fujibayashi S, Neo M, Takemoto M, Ota M, Nakamura T (2010) Paraspinal-approach transforaminal lumbar interbody fusion for the treatment of lumbar foraminal stenosis. J Neurosurg Spine 13:500-508
12. Hench LL (1998) Bioactive materials: the potential for tissue regeneration. J Biomed Mater Res 41:511-518 (Pubitemid 28355434)
13. Jost B, Cripton PA, Lund T, Oxland TR, Lippuner K, Jaeger P et al (1998) Compressive strength of interbody cages in lumbar spine: the effect of cage shape, posterior instrumentation and bone density. Eur Spine J 7:132-141 (Pubitemid 28223599)
14. Kawanabe K, Ise K, Goto K, Akiyama H, Nakamura T, Kaneuji A et al (2009) A new cementless total hip arthroplasty with bioactive titanium porous-coating by alkaline and heat treatment: average 4.8-year results. J Biomed Mater Res Part B: Appl Biomater 90B:476-481
15. Kim HM, Kokubo T, Fujibayashi S, Nishiguchi S, Nakamura T (2000) Bioactive macroporous titanium surface layer on titanium substrate. J Biomed Mater Res 52:553-557
16. Kokubo T (1991) Bioactive glass ceramics: properties and applications. Biomaterials 12:155-163
17. Kokubo T, Kushitani H, Sakka S, Kitsugi T, Yamamuro T (1990) Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W. J Biomed Mater Res 24:721-734 (Pubitemid 20236523)
18. Kokubo T, Miyaji F, Kim HM, Nakamura T (1996) Spontaneous formation of bonelike apatite layer on chemically treated titanium metals. J Am Ceram Soc 79:1127-1129 (Pubitemid 126553709)
19. McClellan JW, Mulconrey DS, Forbes RJ, Fullmer N (2006) Vertebral bone resorption after transforaminal lumbar interbody fusion with bone morphogenetic protein (rhBMP-2). J Spinal Disord Tech 19:483-486 (Pubitemid 44526745)
20. Modic MT, Steinberg PM, Ross JS, Masaryk TJ, Carter JR (1988) Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging. Radiology 166:193-199 (Pubitemid 18027070)
21. Morscher EW, Hefti A, Aebi U (1998) Severe osteolysis after third body wear due to hydroxyapatite particles from acetabular cup coating. J Bone Joint Surg Br 80:267-272
22. Nachemson AL (1981) Disc pressure measurements. Spine 6:93-97 (Pubitemid 11191512)
23. Otsuki B, Takemoto M, Fujibayashi S, Neo M, Kokubo T, Nakamura T (2006) Pore throat size and connectivity determine bone and tissue ingrowth into porous implants: three-dimensional micro-CT based structural analyses of porous bioactive titanium implants. Biomaterials 27:5892-5900 (Pubitemid 44332516)
24. Takemoto M, Fujibayashi S, Neo M, Suzuki J, Kokubo T, Nakamura T (2005) Mechanical properties and osteoconductivity of porous bioactive titanium. Biomaterials 26:6014-6023 (Pubitemid 40812363)
25. Takemoto M, Fujibayashi S, Neo M, Suzuki J, Matsushita T, Kokubo T, Nakamura T (2006) Osteoinductive porous titanium implants: effect of sodium removal by dilute HCl treatment. Biomaterials 27:2682-2691 (Pubitemid 43124104)
26. Takemoto M, Fujibayashi S, Neo M, So K, Akiyama N, Matsushita T et al (2007) A porous bioactive titanium implant for spinal interbody fusion: an experimental study using a canine model. J Neurosurg Spine 7:435-443 (Pubitemid 47584622)
27. Toth JM, Boden SD, Burkus JK MD, Badura JM, Peckham SM, McKay WF (2009) Short-term osteoclastic activity induced by locally high concentrations of recombinant human bone morphogenetic protein-2 in a cancellous bone environment. Spine 34:539-550
28. Tullberg T, Brandt B, Rydberg J, Fritzell P (1996) Fusion rate after posterior lumbar interbody fusion with carbon fiber implant: 1-year follow-up of 51 patients. Eur Spine J 5:178-182 (Pubitemid 26266968)
29. Tullberg T (1998) Failure of a carbon fiber implant: a case report. Spine 23:1804-1806 (Pubitemid 28443087)
30. Vaccaro AR, Lawrence JP, Patel T, Katz LD, Anderson DG, Fischgrund JS et al (2008) The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft in posterolateral lumbar arthrodesis. Spine 33:2850-2862
31. Vaidya R, Sethi A, Bartol S, Jacobson M, Coe C, Craig JG (2008) Complications in the use of rhBMP-2 in PEEK cages for interbody spinal fusions. J Spinal Disord Tech 21:557-562
32. Wen CE, Mabuchi M, Yamada Y, Shimojima K, Chino Y, Asahina T (2001) Processing of biocompatible porous Ti and Mg. Scripta Mater 45:1147-1153 (Pubitemid 32998153)