Type III secretion is essential for the rapidly fatal diarrheal disease caused by non-o1, non-o139 vibrio cholerae

mBio

Volumn 2, Issue 3, 2011, Pages

  Shin, Ok S ^a,d   Tam, Vincent C ^a,e   Suzuki, Masato ^a   Ritchie, Jennifer M ^a,b   Bronson, Roderick T ^a   Waldor, Matthew K ^a,b,c   Mekalanos, John J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d The Catholic University of Korea College of Medicine   (South Korea)

^e INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CHOLERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIARRHEA; DISEASE SEVERITY; HISTOPATHOLOGY; IN VIVO STUDY; INTESTINE EPITHELIUM; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN TRANSPORT; RABBIT; TYPE III SECRETION SYSTEM; VIBRIO CHOLERAE; WILD TYPE; ANIMAL; GENE DELETION; GENETICS; INTESTINE MUCOSA; METABOLISM; MICROBIOLOGY; NEWBORN; PATHOGENICITY; PATHOLOGY; SMALL INTESTINE;

ANIMALIA; ORYCTOLAGUS CUNICULUS; VIBRIO CHOLERAE;

CARRIER PROTEIN; VIRULENCE FACTOR;

ANIMALS; ANIMALS, NEWBORN; CHOLERA; GENE DELETION; INTESTINAL MUCOSA; INTESTINE, SMALL; MEMBRANE TRANSPORT PROTEINS; RABBITS; VIBRIO CHOLERAE NON-O1; VIRULENCE FACTORS;

EID: 84855187956     PISSN: None     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00106-11     Document Type: Article

References (37)

1. Faruque SM, et al. 2004. Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic area. Proc. Natl. Acad. Sci. U. S. A. 101:2123-2128.
2. Bag PK, et al. 2008. Putative virulence traits and pathogenicity of Vibrio cholerae non-O1, non-O139 isolates from surface waters in Kolkata, India. Appl. Environ. Microbiol. 74:5635-5644.
3. Bagchi K, et al. 1993. Epidemic of diarrhea caused by Vibrio cholerae non-O1 that produced heat-stable toxin among Khmers in a camp in Thailand. J. Clin. Microbiol. 31:1315-1317.
4. Chatterjee S, et al. 2009. Incidence, virulence factors, and clonality among clinical strains of non-O1, non-O139 Vibrio cholerae isolates from hospitalized diarrheal patients in Kolkata, India. J. Clin. Microbiol. 47: 1087-1095.
5. Dalsgaard A, et al. 1995. Characterization of Vibrio cholerae non-O1 serogroups obtained from an outbreak of diarrhea in Lima, Peru. J. Clin. Microbiol. 33:2715-2722.
6. Dalsgaard A, Serichantalergs O, Pitarangsi C, Echeverria P. 1995. Molecular characterization and antibiotic susceptibility of Vibrio cholerae non-O1. Epidemiol. Infect. 114:51-63.
7. Sharma C, et al. 1998. Molecular analysis of non-O1, non-O139 Vibrio cholerae associated with an unusual upsurge in the incidence of choleralike disease in Calcutta, India. J. Clin. Microbiol. 36:756-763.
8. Morris JG, Jr, et al. 1981. Non-O group 1 Vibrio cholerae gastroenteritis in the United States: clinical, epidemiologic, and laboratory characteristics of sporadic cases. Ann. Intern. Med. 94:656-658.
9. Tam VC, Serruto D, Dziejman M, Brieher W, Mekalanos JJ. 2007. A type III secretion system in Vibrio cholerae translocates a formin/spire hybrid-like actin nucleator to promote intestinal colonization. Cell Host Microbe 1:95-107.
10. Dziejman M, et al. 2005. Genomic characterization of non-O1, non- O139 Vibrio cholerae reveals genes for a type III secretion system. Proc. Natl. Acad. Sci. U. S. A. 102:3465-3470.
11. Cornelis GR, Van Gijsegem F. 2000. Assembly and function of type III secretory systems. Annu. Rev. Microbiol. 54:735-774.
12. Galán JE, Collmer A. 1999. Type III secretion machines: bacterial devices for protein delivery into host cells. Science 284:1322-1328.
13. Hueck CJ. 1998. Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol. Mol. Biol. Rev. 62:379-433.
14. Caron E, et al. 2006. Subversion of actin dynamics by EPEC and EHEC. Curr. Opin. Microbiol. 9:40-45.
15. Parsot C. 2009. Shigella type III secretion effectors: how, where, when, for what purposes? Curr. Opin. Microbiol. 12:110-116.
16. Patel JC, Galán JE. 2005. Manipulation of the host actin cytoskeleton by Salmonella-all in the name of entry. Curr. Opin. Microbiol. 8:10-15.
17. Galán JE. 2009. Common themes in the design and function of bacterial effectors. Cell Host Microbe 5:571-579.
18. Kim M, et al. 2010. Bacterial interactions with the host epithelium. Cell Host Microbe 8:20-35.
19. Mattoo S, Lee YM, Dixon JE. 2007. Interactions of bacterial effector proteins with host proteins. Curr. Opin. Immunol. 19:392-401.
20. Tam VC, et al. 2010. Functional analysis of VopF activity required for colonization in Vibrio cholerae. mBio 1(5):e00289-10.
21. Dalsgaard A, et al. 2001. Clinical and environmental isolates of Vibrio cholerae serogroup O141 carry the CTX phage and the genes encoding the toxin-coregulated pili. J. Clin. Microbiol. 39:4086-4092.
22. Ritchie JM, Rui H, Bronson RT, Waldor MK. 2010. Back to the future: studying cholera pathogenesis using infant rabbits. mBio 1(1):e00047-10.
23. Rui H, et al. 2010. Reactogenicity of live-attenuated Vibrio cholerae vaccines is dependent on flagellins. Proc. Natl. Acad. Sci. U. S. A. 107: 4359-4364.
24. Zheng J, Shin OS, Cameron DE, Mekalanos JJ. 2010. Quorum sensing and a global regulator TsrA control expression of type VI secretion and virulence in Vibrio cholerae. Proc. Natl. Acad. Sci. U. S. A. 107: 21128-21133.
25. Rudra S, Mahajan R, Mathur M, Kathuria K, Talwar V. 1996. Cluster of cases of clinical cholera due to Vibrio cholerae 010 in east Delhi. Indian J. Med. Res. 103:71-73.
26. Nelson ET, Clements JD, Finkelstein RA. 1976. Vibrio cholerae adherence and colonization in experimental cholera: electron microscopic studies. Infect. Immun. 14:527-547.
27. Dowling AJ, et al. 2004. The insecticidal toxin Makes caterpillars floppy (Mcf) promotes apoptosis in mammalian cells. Cell. Microbiol. 6:345-353.
28. Waterfield N, Hares M, Yang G, Dowling A, Ffrench-Constant R. 2005. Potentiation and cellular phenotypes of the insecticidal toxin complexes of Photorhabdus bacteria. Cell. Microbiol. 7:373-382.
29. Waterfield N, Kamita SG, Hammock BD, Ffrench-Constant R. 2005. The Photorhabdus Pir toxins are similar to a developmentally regulated insect protein but show no juvenile hormone esterase activity. FEMS Microbiol. Lett. 245:47-52.
30. Gendlina I, et al. 2007. Identification and type III-dependent secretion of the Yersinia pestis insecticidal-like proteins. Mol. Microbiol. 64: 1214-1227.
31. Satchell KJ. 2007. MARTX, multifunctional autoprocessing repeats-intoxin toxins. Infect. Immun. 75:5079-5084.
32. National Research Council. 1996. Guide for the care and use of laboratory animals. National Academy Press, Washington, DC.
33. National Institutes of Health. 2002. Public Health Service policy on humane care and use of laboratory animals. Office of Laboratory Animal Welfare, National Institutes of Health, Bethesda, MD.
34. U.S. Office of Science and Technology Policy. 1985. Laboratory animal welfare; U.S. government principles for the utilization and care of vertebrate animals used in testing, research and training. Fed. Regist. 50(97): 20864-20865.
35. Skorupski K, Taylor RK. 1996. Positive selection vectors for allelic exchange. Gene 169:47-52.
36. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2- ΔΔCT method. Methods 25:402-408.
37. Charpentier X, Oswald E. 2004. Identification of the secretion and translocation domain of the enteropathogenic and enterohemorrhagic Escherichia coli effector Cif, using TEM-1 beta-lactamase as a new fluorescencebased reporter. J. Bacteriol. 186:5486-5495.