Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population

Rheumatology

Volumn 51, Issue 1, 2012, Pages 87-92

  Järvinen, Tiina M ^a,b,c,d,e   Hellquist, Anna ^a   Zucchelli, Marco ^a   Koskenmies, Sari ^b,c,d   Panelius, Jaana ^b   Hasan, Taina ^f   Julkunen, Heikki ^g   D'Amato, Mauro ^a   Kere, Juha ^a,b,c,d,e  

^a KAROLINSKA INSTITUTE   (Sweden)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e FOLKHÄLSAN INSTITUTE OF GENETICS   (Finland)

^f TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^g PEIJAS HOSPITAL   (Finland)

Author keywords

B cell receptor pathway; Epistasis; Finnish population; Genome wide association study replication; Interferon regulatory factor 5 transportin 3

Indexed keywords

INTERFERON REGULATORY FACTOR 5;

ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE INTERACTION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS;

CASE-CONTROL STUDIES; EPISTASIS, GENETIC; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INTERFERON REGULATORY FACTORS; LINKAGE DISEQUILIBRIUM; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION;

EID: 84855179152     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ker263     Document Type: Article

References (20)

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