Dysexecutive functioning in mild cognitive impairment: Derailment in temporal gradients

Journal of the International Neuropsychological Society

Volumn 18, Issue 1, 2012, Pages 20-28

  Eppig, Joel ^a   Wambach, Denene ^a   Nieves, Christine ^a   Price, Catherine C ^b   Lamar, Melissa ^c   Delano Wood, Lisa ^d   Giovannetti, Tania ^e   Bettcher, Brianne M ^f   Penney, Dana L ^f   Swenson, Rod ^g   Lippa, Carol ^a   Kabasakalian, Anahid ^a   Bondi, Mark W ^d   Libon, David J ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e TEMPLE UNIVERSITY   (United States)

^f LAHEY HOSPITAL AND MEDICAL CENTER   (United States)

^g UND School of Medicine & Health Sciences Southeast Campus   (United States)

Author keywords

Alzheimer's disease; Executive control; Mild cognitive impairment; Multiple domain mild cognitive impairment; Single domain mild cognitive impairment; The Titanic Effect

Indexed keywords

EID: 84855167032     PISSN: 13556177     EISSN: 14697661     Source Type: Journal    
DOI: 10.1017/S1355617711001238     Document Type: Article

References (39)

1. Albert, M.S., DeKosky, S.T., Dickson, D., Dubois, B., Feldman, H.H., Fox, N.C., y Phelps, C.H. (2011). The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging and Alzheimer's Association workgroup. Alzheimer's and Dementia, 7, 1-10.
2. Alexander, G.E., DeLong, M.R., & Strick, P.L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual Review of Neuroscience, 9, 357-381. (Pubitemid 16055790)
3. Busse, A., Hensel, A., Gühne, U., Angermeyer, M.C., & Riedel- Heller, S.G. (2006). Mild cognitive impairment: Long-term course of four clinical subtypes. Neurology, 67, 2176-2185. (Pubitemid 46035473)
4. Carew, T.G., Cloud, B.S., Lamar, M., Grossman, M., & Libon, D.J. (1997). Patterns of Impairment in category fluency in Alzheimer's disease and ischemic vascular dementia. Neuropsychology, 11, 400-412. (Pubitemid 27294663)
5. Chao, L.L., Pa, J., Duarte, A., Schuff, N., Weiner, M.W., Kramer, J.H.,yJohnson, J.K. (2009). Patterns of cerebral hypoperfusion in amnestic and dysexecutive MCI. Alzheimer Disease Association and Related Disorders, 23, 245-252.
6. Delano-Wood, L., Bondi, M.W., Sacco, J., Abeles, N., Jak, A.J., Libon, D.J., & Bozoki, A. (2010). Heterogeneity in mild cognitive impairment: Differences in neuropsychological profile and associated white matter lesion pathology. Journal of the International Neuropsychological Society, 15, 906-914.
7. Delano-Wood, L., Libon, D.J., Cabrera, Y., Nation, D., Eppig, J., Dhanani, J., y Bondi, M.W. (2011, July). Verbal fluency performance is associated with elevated stroke risk in nonamnestic MCI: A process and errors analytic approach. To be presented at the 2011 Alzheimer's Association International Conference on Alzheimer's Disease, Paris, France.
8. Fischer, P., Jungwirth, S., Zehetmayer, S., Weissgram, S., Hoenigschnabl, S., Gelpi, E.,yKragl, K.H. (2007). Conversion from subtypes of mild cognitive impairment to Alzheimer dementia. Archives of Neurology, 68, 288-291. (Pubitemid 46148341)
9. Folstein, M.F., Folstein, S.E., & McHugh, P.R. (1975). Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189-198.
10. Fuster, J.M. (1997). The prefrontal cortex: Anatomy, physiology, and neuropsychology of the executive lobe (2nd ed.). New York, NY: Lippincott-Raven Press.
11. Kaplan, E. (1988). A process approach to neuropsychological assessment. In T. Boll & B.K. Bryant (Eds.), Clinical neuropsychology and brain function: Research, measurement, and practice (pp. 129-167).Washington, DC: American Psychological Association.
12. Kaplan, E., Fein, D., Morris, R.G., & Delis, D.C. (1991). The Wechsler Adult Intelligence Scale-Revised as a neuropsychological instrument manual. San Antonio, TX: Psychological Corporation.
13. Kaplan, E., Goodglass, H., & Weintraub, S. (1983). The Boston Naming Test. Philadelphia, PA: Lea and Febiger.
14. Kaufman, L., Ischebeck, A., Weiss, E., Koppelstaetter, F., Siedentopf, C., Vogel, S., y Wood, G. (2008). An fMRI study of the numerical Stroop task in individuals with and without minimal cognitive impairment. Cortex, 44, 1248-1255.
15. Lamar, M., Catani, M., Price, C.C., Heilman, K.M., & Libon, D.J. (2008). The impact of region specific leukoaraiosis on working memory deficits in dementia. Neuropsychologia, 46, 2597-2601.
16. Lamar, M., Podell, K., Carew, T.G., Cloud, B.S., Kennedy, C., Goldberg, E., Kaplan, E., & Libon, D.J. (1997). Perseverative behavior in Alzheimer's disease and subcortical ischaemic vascular dementia. Neuropsychologia, 11, 523-534. (Pubitemid 27459759)
17. Lamar, M., Price, C.C., Davis, K.L., Kaplan, E., & Libon, D.J. (2002). Capacity to maintain mental set in dementia. Neuropsychologia, 40, 435-445. (Pubitemid 33000480)
18. Lamar, M., Price, C.C., Giovannetti, T., Swenson, R., & Libon, D.J. (2010). The dysexecutive syndrome associated with subcortical white matter disease and related white matter pathology. Behavioural Neurology, 22, 53-62.
19. Lamar, M., Price, C.C., Libon, D.J., Penney, D.L., Kaplan, E., Grossman, M., & Heilman, K.M. (2007). Alterations in working memory as a function of leukoaraiosis in dementia. Neuropsychologia, 45, 245-254. (Pubitemid 44828784)
20. Lawton, M.P., & Brody, E. (1968). Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist, 9, 179-186.
21. Leach, L., Kaplan, E., Rewilak, D., Richards, B., & Proulx, G.B. (2000). The Kaplan Baycrest Neurocognitive Assessment. San Antonio, TX: The Psychological Corporation.
22. Libon, D.J., Bondi, M.W., Price, C.C., Lamar, M., Eppig, J., Wambach, D.M., y Penney, D.L. (2011). Verbal serial list learning in mild cognitive impairment: A profile analysis of interference, forgetting, and errors. Journal of the International Neuropsychological Society, 2011, 17, 905-914.
23. Libon, D.J., Eppig, J., Xie, X.S., Wicas, G., Lippa, C., Bettcher, B.M., y Wambach, D. (2010). The heterogeneity of mild cognitive impairment: A neuropsychological analysis. Journal of the International Neuropsychological Association, 16, 84-93.
24. Lopez, O.L., Jagust, W.J., DeKosky, S.T., Becker, J.T., Fitzpatrick, A., Dulberg, C., y Kuller, L.H. (2003). Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study. Archives of Neurology, 60, 1385-1399.
25. Monsch, A., Bondi, M., Butters, N., Salmon, D.P., Katzman, R., & Thal, L.J. (1992). Comparison of verbal fluency tasks in the detection of dementia of the Alzheimer's type. Archives of Neurology, 49, 1253-1258.
26. Pa, J., Boxer, A., Chao, L.L., Gazzaley, A., Freeman, K., Kramer, J., yJohnson, J.K. (2009). Clinical-neuroimaging characteristics of dysexecutive mild cognitive impairment. Annuals of Neurology, 65, 414-423.
27. Pare, D., Curro-Dossi, R., & Steriade, M. (1991). Three types of inhibitory postsynaptic potentials generated by inter neurons in the anterior thalamic complex of the cat. Journal of Neurophysiology, 66, 1190-1204.
28. Petersen, R.C., & Morris, J.D. (2005). Mild cognitive impairment as a clinical entity and treatment target. Archives of Neurology, 62, 1160-1163. (Pubitemid 41043744)
29. Petersen, R.C., Roberts, R.O., Knopman, D.S., Boeve, B.F., Geda, Y.E., Ivnik, R.J., y Jack, C.R., Jr. (2009). Mild cognitive impairment: Ten years later. Archives of Neurology, 66, 1447-1455.
30. Price, C.C., Brumback, B., Towler, S., Mitchell, S., Tanner, J., Lamar, y Libon, D.J. (2011, February). Re-examination of the 25% threshold for symptomatic leukoaraiosis. In D.J. Libon (Chair) The differential contribution of white and gray matter to the phenotypic expression of dementia. Symposium Presentation at the 39th annual meeting of The International Neuropsychological Society, Boston, MA.
31. Price, C.C., Garrett, K.D., Jefferson, A.L., Cosentino, S., Tanner, J., Penney, D.L., y Libon, D.J. (2009). The role of leukoaraiosis severity on learning and memory in dementia: Performance differences on a 9-word list learning test. The Clinical Neuropsychologist, 23, 1-18.
32. Solfrizzi, V., Panza, F., Colacicco, A.M., D'Introno, A., Capurso, C., Torres, F., y Capurso, A. (2004). Vascular risk factors, incidence of MCI, and rates of progression to dementia. Neurology, 63, 1882-1891. (Pubitemid 39532385)
33. Steriade, M. (2004). Local gating of information processing through the thalamus. Neuron, 41, 493-494. (Pubitemid 38253062)
34. Stuss, D.T., Shallice, T., Alexander, M.P., & Picton, T.W. (1995). A multidisciplinary approach to anterior attentional functions. Annals of the New York Academy of Sciences, 769, 191-211. (Pubitemid 26075893)
35. Wechsler, D. (1945). A standardized memory test for clinical use. Journal of Psychology, 19, 87-95.
36. Wechsler, D. (1981). The Wechsler Adult Intelligence Scale- Revised. San Antonio, TX: Psychology Corporation.
37. Winblad, B., Palmer, K., Kivipelto, M., Jelic, V., Fratiglioni, L., Wahlund, L.O., y Petersen, R.C. (2004). Mild cognitive impairment - beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment. Journal of Internal Medicine, 256, 240-246. (Pubitemid 39222993)
38. Yaffe, K., Petersen, R.C., Lindquist, K., Kramer, J., & Miller, B. (2006). Subtype of mild cognitive impairment and progression to dementia and death. Dementia and Geriatric Cognitive Disorders, 22, 312-319. (Pubitemid 44651445)
39. Yesavage, J.A., Brink, T.L., Rose, T.L., Lum, O., Huang, V., & Adey, M. (1983). Development and validation of a geriatric depression severity scale: A preliminary report. Journal of Psychiatric Research, 17, 37-49. (Pubitemid 13123113)