Clinical significance of microsatellite instability for stage II or III colorectal cancer following adjuvant therapy with doxifluridine

Medical Oncology

Volumn 28, Issue SUPPL. 1, 2011, Pages

  Kang, Byung Woog ^a   Kim, Jong Gwang ^a   Lee, Soo Jung ^a   Chae, Yee Soo ^a   Moon, Joon Ho ^a   Sohn, Sang Kyun ^a   Jeon, Seong Woo ^a   Jung, Min Kyu ^a   Lim, Kyoung Hoon ^a   Jang, You Seok ^a   Park, Jun Seok ^a   Jun, Soo Han ^a   Choi, Gyu Seog ^a  

^a Kyungpook National University Hospital   (South Korea)

Author keywords

Adjuvant therapy; Colorectal cancer; Doxifluridine; Microsatellite instability

Indexed keywords

DOXIFLURIDINE; TUMOR MARKER; TUMOR MARKER BAT25; TUMOR MARKER BAT26; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER STAGING; CANCER SURGERY; COLORECTAL CANCER; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; OVERALL SURVIVAL; PRIORITY JOURNAL; RECURRENCE FREE SURVIVAL;

EID: 84655176736     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-010-9701-2     Document Type: Article

References (22)

1. FA Sinicrope DJ Sargent 2009 Clinical implications of microsatellite instability in sporadic colon cancers Curr Opin Oncol 21 369 373
2. CR Boland SN Thibodeau SR Hamilton D Sidransky JR Eshleman RW Burt 1998 A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer Cancer Res 58 5248 5257 (Pubitemid 28521189)
3. R Gryfe H Kim ET Hsieh MD Aronson EJ Holowaty SB Bull 2000 Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer N Engl J Med 342 69 77 (Pubitemid 30036597)
4. S Popat R Hubner RS Houlston 2005 Systematic review of microsatellite instability and colorectal cancer prognosis J Clin Oncol 23 609 618 (Pubitemid 46224239)
5. CM Ribic DJ Sargent MJ Moore SN Thibodeau AJ French RM Goldberg 2003 Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer N Engl J Med 349 247 257 (Pubitemid 36859476)
6. WS Samowitz K Curtin KN Ma D Schaffer LW Coleman M Leppert 2001 Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level Cancer Epidemiol Biomarkers Prev 10 917 923 (Pubitemid 32844897)
7. D Cunningham W Atkin HJ Lenz HT Lynch B Minsky B Nordlinger 2010 Colorectal cancer Lancet 375 1030 1047
8. G Des Guetz B Uzzan P Nicolas O Schischmanoff GY Perret JF Morere 2009 Microsatellite instability does not predict the efficacy of chemotherapy in metastatic colorectal cancer. A systematic review and meta-analysis Anticancer Res 29 1615 1620
9. R Jover P Zapater A Castells X Llor M Andreu J Cubiella 2009 The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status Eur J Cancer 45 365 373
10. MM Bertagnolli D Niedzwiecki CC Compton HP Hahn M Hall B Damas 2009 Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803 J Clin Oncol 27 1814 1821
11. LH Jensen KD Danenberg PV Danenberg A Jakobsen 2007 Predictive value of MSH2 gene expression in colorectal cancer treated with capecitabine Clin Colorectal Cancer 6 433 435 (Pubitemid 46658517)
12. H Niitani K Kimura T Saito I Nakao O Abe I Urushizaki 1985 Phase II study of 5′-deoxy-5-fluorouridine (5′-DFUR) in patients with malignant cancer-a multi-institutional cooperative study Gan To Kagaku Ryoho 12 2044 2051 (Pubitemid 17215003)
13. M Miwa M Ura M Nishida N Sawada T Ishikawa K Mori 1998 Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue Eur J Cancer 34 1274 1281 (Pubitemid 28342121)
14. WS Jo JM Carethers 2006 Chemotherapeutic implications in microsatellite unstable colorectal cancer Cancer Biomark 2 51 60
15. AM Bellizzi WL Frankel 2009 Colorectal cancer due to deficiency in DNA mismatch repair function: a review Adv Anat Pathol 16 405 417
16. DJ Sargent S Marsoni G Monges SN Thibodeau R Labianca SR Hamilton 2010 Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer J Clin Oncol 28 3219 3226
17. H Elsaleh D Joseph F Grieu N Zeps N Spry B Iacopetta 2000 Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer Lancet 355 1745 1750 (Pubitemid 30265078)
18. GP Kim LH Colangelo HS Wieand S Paik IR Kirsch N Wolmark 2007 Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study J Clin Oncol 25 767 772 (Pubitemid 350002875)
19. C Lamberti S Lundin M Bogdanow C Pagenstecher N Friedrichs R Buttner 2007 Microsatellite instability did not predict individual survival of unselected patients with colorectal cancer Int J Colorectal Dis 22 145 152 (Pubitemid 44964017)
20. ST Kim J Lee SH Park JO Park HY Lim WK Kang 2010 Clinical impact of microsatellite instability in colon cancer following adjuvant FOLFOX therapy Cancer Chemother Pharmacol 66 4 659 667
21. Y Yamada 2008 Current status of chemotherapy for advanced colorectal cancer in Japan Clin Colorectal Cancer 7 15 24 (Pubitemid 351252447)
22. A Walther E Johnstone C Swanton R Midgley I Tomlinson D Kerr 2009 Genetic prognostic and predictive markers in colorectal cancer Nat Rev Cancer 9 489 499